BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

245 related articles for article (PubMed ID: 7540935)

  • 1. Mechanism of inhibition of HIV-1 reverse transcriptase by non-nucleoside inhibitors.
    Esnouf R; Ren J; Ross C; Jones Y; Stammers D; Stuart D
    Nat Struct Biol; 1995 Apr; 2(4):303-8. PubMed ID: 7540935
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crystal structures of 8-Cl and 9-Cl TIBO complexed with wild-type HIV-1 RT and 8-Cl TIBO complexed with the Tyr181Cys HIV-1 RT drug-resistant mutant.
    Das K; Ding J; Hsiou Y; Clark AD; Moereels H; Koymans L; Andries K; Pauwels R; Janssen PA; Boyer PL; Clark P; Smith RH; Kroeger Smith MB; Michejda CJ; Hughes SH; Arnold E
    J Mol Biol; 1996 Dec; 264(5):1085-100. PubMed ID: 9000632
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The structure of HIV-1 reverse transcriptase complexed with 9-chloro-TIBO: lessons for inhibitor design.
    Ren J; Esnouf R; Hopkins A; Ross C; Jones Y; Stammers D; Stuart D
    Structure; 1995 Sep; 3(9):915-26. PubMed ID: 8535785
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure of HIV-1 reverse transcriptase in a complex with the non-nucleoside inhibitor alpha-APA R 95845 at 2.8 A resolution.
    Ding J; Das K; Tantillo C; Zhang W; Clark AD; Jessen S; Lu X; Hsiou Y; Jacobo-Molina A; Andries K
    Structure; 1995 Apr; 3(4):365-79. PubMed ID: 7542140
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance.
    Tantillo C; Ding J; Jacobo-Molina A; Nanni RG; Boyer PL; Hughes SH; Pauwels R; Andries K; Janssen PA; Arnold E
    J Mol Biol; 1994 Oct; 243(3):369-87. PubMed ID: 7525966
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High resolution structures of HIV-1 RT from four RT-inhibitor complexes.
    Ren J; Esnouf R; Garman E; Somers D; Ross C; Kirby I; Keeling J; Darby G; Jones Y; Stuart D
    Nat Struct Biol; 1995 Apr; 2(4):293-302. PubMed ID: 7540934
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors.
    Hopkins AL; Ren J; Esnouf RM; Willcox BE; Jones EY; Ross C; Miyasaka T; Walker RT; Tanaka H; Stammers DK; Stuart DI
    J Med Chem; 1996 Apr; 39(8):1589-600. PubMed ID: 8648598
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The structure of unliganded reverse transcriptase from the human immunodeficiency virus type 1.
    Rodgers DW; Gamblin SJ; Harris BA; Ray S; Culp JS; Hellmig B; Woolf DJ; Debouck C; Harrison SC
    Proc Natl Acad Sci U S A; 1995 Feb; 92(4):1222-6. PubMed ID: 7532306
    [TBL] [Abstract][Full Text] [Related]  

  • 9. HEPT derivatives as non-nucleoside inhibitors of HIV-1 reverse transcriptase: QSAR studies agree with the crystal structures.
    Gaudio AC; Montanari CA
    J Comput Aided Mol Des; 2002 Apr; 16(4):287-95. PubMed ID: 12400858
    [TBL] [Abstract][Full Text] [Related]  

  • 10. [HEPT and its related compounds as anti-HIV agents].
    Miyasaka T; Tanaka H; Baba M
    Nihon Rinsho; 1993 Sep; 51 Suppl():200-6. PubMed ID: 7505847
    [No Abstract]   [Full Text] [Related]  

  • 11. 2.2 A resolution structure of the amino-terminal half of HIV-1 reverse transcriptase (fingers and palm subdomains).
    Unge T; Knight S; Bhikhabhai R; Lövgren S; Dauter Z; Wilson K; Strandberg B
    Structure; 1994 Oct; 2(10):953-61. PubMed ID: 7532533
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Resistance to 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives is generated by mutations at multiple sites in the HIV-1 reverse transcriptase.
    Buckheit RW; Fliakas-Boltz V; Yeagy-Bargo S; Weislow O; Mayers DL; Boyer PL; Hughes SH; Pan BC; Chu SH; Bader JP
    Virology; 1995 Jun; 210(1):186-93. PubMed ID: 7540784
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Identification of a putative binding site for [2',5'-bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine (TSAO) derivatives at the p51-p66 interface of HIV-1 reverse transcriptase.
    Rodríguez-Barrios F; Pérez C; Lobatón E; Velázquez S; Chamorro C; San-Félix A; Pérez-Pérez MJ; Camarasa MJ; Pelemans H; Balzarini J; Gago F
    J Med Chem; 2001 Jun; 44(12):1853-65. PubMed ID: 11384232
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Collective motions in HIV-1 reverse transcriptase: examination of flexibility and enzyme function.
    Bahar I; Erman B; Jernigan RL; Atilgan AR; Covell DG
    J Mol Biol; 1999 Jan; 285(3):1023-37. PubMed ID: 9887265
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The Lys103Asn mutation of HIV-1 RT: a novel mechanism of drug resistance.
    Hsiou Y; Ding J; Das K; Clark AD; Boyer PL; Lewi P; Janssen PA; Kleim JP; Rösner M; Hughes SH; Arnold E
    J Mol Biol; 2001 Jun; 309(2):437-45. PubMed ID: 11371163
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure of unliganded HIV-1 reverse transcriptase at 2.7 A resolution: implications of conformational changes for polymerization and inhibition mechanisms.
    Hsiou Y; Ding J; Das K; Clark AD; Hughes SH; Arnold E
    Structure; 1996 Jul; 4(7):853-60. PubMed ID: 8805568
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nucleoside drug resistance in HIV-1 reverse transcriptase.
    Yadav PN; Yadav JS; Modak MJ
    Nat Struct Biol; 1995 Mar; 2(3):193-5. PubMed ID: 7539709
    [No Abstract]   [Full Text] [Related]  

  • 18. Chimeric HIV-1 and feline immunodeficiency virus reverse transcriptases: critical role of the p51 subunit in the structural integrity of heterodimeric lentiviral DNA polymerases.
    Amacker M; Hübscher U
    J Mol Biol; 1998 May; 278(4):757-65. PubMed ID: 9614940
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Structure of HIV-1 RT/TIBO R 86183 complex reveals similarity in the binding of diverse nonnucleoside inhibitors.
    Ding J; Das K; Moereels H; Koymans L; Andries K; Janssen PA; Hughes SH; Arnold E
    Nat Struct Biol; 1995 May; 2(5):407-15. PubMed ID: 7545077
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structural basis of asymmetry in the human immunodeficiency virus type 1 reverse transcriptase heterodimer.
    Wang J; Smerdon SJ; Jäger J; Kohlstaedt LA; Rice PA; Friedman JM; Steitz TA
    Proc Natl Acad Sci U S A; 1994 Jul; 91(15):7242-6. PubMed ID: 7518928
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.