132 related articles for article (PubMed ID: 7540950)
1. Metabolism and actions of 2-chloro-9-(2-deoxy-2-fluoro-beta-D- arabinofuranosyl)-adenine in human lymphoblastoid cells.
Xie C; Plunkett W
Cancer Res; 1995 Jul; 55(13):2847-52. PubMed ID: 7540950
[TBL] [Abstract][Full Text] [Related]
2. Effects of 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine on K562 cellular metabolism and the inhibition of human ribonucleotide reductase and DNA polymerases by its 5'-triphosphate.
Parker WB; Shaddix SC; Chang CH; White EL; Rose LM; Brockman RW; Shortnacy AT; Montgomery JA; Secrist JA; Bennett LL
Cancer Res; 1991 May; 51(9):2386-94. PubMed ID: 1707752
[TBL] [Abstract][Full Text] [Related]
3. Deoxynucleotide pool depletion and sustained inhibition of ribonucleotide reductase and DNA synthesis after treatment of human lymphoblastoid cells with 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) adenine.
Xie KC; Plunkett W
Cancer Res; 1996 Jul; 56(13):3030-7. PubMed ID: 8674058
[TBL] [Abstract][Full Text] [Related]
4. Comparison of the mechanism of cytotoxicity of 2-chloro-9-(2-deoxy-2- fluoro-beta-D-arabinofuranosyl)adenine, 2-chloro-9-(2-deoxy-2-fluoro- beta-D-ribofuranosyl)adenine, and 2-chloro-9-(2-deoxy-2,2-difluoro- beta-D-ribofuranosyl)adenine in CEM cells.
Parker WB; Shaddix SC; Rose LM; Shewach DS; Hertel LW; Secrist JA; Montgomery JA; Bennett LL
Mol Pharmacol; 1999 Mar; 55(3):515-20. PubMed ID: 10051535
[TBL] [Abstract][Full Text] [Related]
5. A comparison of the transportability, and its role in cytotoxicity, of clofarabine, cladribine, and fludarabine by recombinant human nucleoside transporters produced in three model expression systems.
King KM; Damaraju VL; Vickers MF; Yao SY; Lang T; Tackaberry TE; Mowles DA; Ng AM; Young JD; Cass CE
Mol Pharmacol; 2006 Jan; 69(1):346-53. PubMed ID: 16234483
[TBL] [Abstract][Full Text] [Related]
6. Metabolic basis of arabinonucleoside selectivity for human leukemic T- and B-lymphoblasts.
Verhoef V; Fridland A
Cancer Res; 1985 Aug; 45(8):3646-50. PubMed ID: 2410098
[TBL] [Abstract][Full Text] [Related]
7. Preclinical antitumor activity of 2-chloro-9-(2-deoxy-2-fluoro-beta-D- arabinofuranosyl)adenine (Cl-F-ara-A).
Waud WR; Schmid SM; Montgomery JA; Secrist JA
Nucleosides Nucleotides Nucleic Acids; 2000; 19(1-2):447-60. PubMed ID: 10772726
[TBL] [Abstract][Full Text] [Related]
8. Metabolism and action of fludarabine phosphate.
Plunkett W; Huang P; Gandhi V
Semin Oncol; 1990 Oct; 17(5 Suppl 8):3-17. PubMed ID: 1699280
[TBL] [Abstract][Full Text] [Related]
9. DNA repair initiated in chronic lymphocytic leukemia lymphocytes by 4-hydroperoxycyclophosphamide is inhibited by fludarabine and clofarabine.
Yamauchi T; Nowak BJ; Keating MJ; Plunkett W
Clin Cancer Res; 2001 Nov; 7(11):3580-9. PubMed ID: 11705880
[TBL] [Abstract][Full Text] [Related]
10. Mechanisms of the apoptotic activity of Cl-F-araA in a human T-ALL cell line, CCRF-CEM.
Takahashi T; Shimizu M; Akinaga S
Cancer Chemother Pharmacol; 2002 Sep; 50(3):193-201. PubMed ID: 12203101
[TBL] [Abstract][Full Text] [Related]
11. A proposed mechanism for the selective inhibition of human cytomegalovirus replication by 1-(2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-fluorouracil.
Suzuki S; Misra HK; Wiebe LI; Knaus EE; Tyrrell DL
Mol Pharmacol; 1987 Mar; 31(3):301-6. PubMed ID: 3031445
[TBL] [Abstract][Full Text] [Related]
12. Arabinosylguanine-induced apoptosis of T-lymphoblastic cells: incorporation into DNA is a necessary step.
Rodriguez CO; Gandhi V
Cancer Res; 1999 Oct; 59(19):4937-43. PubMed ID: 10519407
[TBL] [Abstract][Full Text] [Related]
13. A new high-performance liquid chromatography method determines low production of 9-beta-D-arabinofuranosylguanine triphosphate, an active metabolite of nelarabine, in adult T-cell leukemia cells.
Yamauchi T; Nishi R; Kitazumi K; Nakano T; Ueda T
Oncol Rep; 2010 Feb; 23(2):499-504. PubMed ID: 20043113
[TBL] [Abstract][Full Text] [Related]
14. Incorporation of fludarabine and 1-beta-D-arabinofuranosylcytosine 5'-triphosphates by DNA polymerase alpha: affinity, interaction, and consequences.
Gandhi V; Huang P; Chapman AJ; Chen F; Plunkett W
Clin Cancer Res; 1997 Aug; 3(8):1347-55. PubMed ID: 9815818
[TBL] [Abstract][Full Text] [Related]
15. Inhibition of primer RNA formation in CCRF-CEM leukemia cells by fludarabine triphosphate.
Catapano CV; Chandler KB; Fernandes DJ
Cancer Res; 1991 Apr; 51(7):1829-35. PubMed ID: 1706219
[TBL] [Abstract][Full Text] [Related]
16. Comparison of the actions of 9-beta-D-arabinofuranosyl-2-fluoroadenine and 9-beta-D-arabinofuranosyladenine on target enzymes from mouse tumor cells.
White EL; Shaddix SC; Brockman RW; Bennett LL
Cancer Res; 1982 Jun; 42(6):2260-4. PubMed ID: 7042080
[TBL] [Abstract][Full Text] [Related]
17. Pharmacokinetics of the anticancer agent 2-chloro-9-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine in rats.
Qian M; Wang X; Shanmuganathan K; Chu CK; Gallo JM
Cancer Chemother Pharmacol; 1994; 33(6):484-8. PubMed ID: 8137458
[TBL] [Abstract][Full Text] [Related]
18. Action of 9-beta-D-arabinofuranosyl-2-fluoroadenine on RNA metabolism.
Huang P; Plunkett W
Mol Pharmacol; 1991 Apr; 39(4):449-55. PubMed ID: 1708088
[TBL] [Abstract][Full Text] [Related]
19. Metabolism of 1-beta-D-arabinofuranosyl-5-azacytosine and incorporation into DNA of human T-lymphoblastic cells (Molt-4).
Townsend A; Leclerc JM; Dutschman G; Cooney D; Cheng YC
Cancer Res; 1985 Aug; 45(8):3522-8. PubMed ID: 2410096
[TBL] [Abstract][Full Text] [Related]
20. Biochemical pharmacology and resistance to 2-chloro-2'-arabino-fluoro-2'-deoxyadenosine, a novel analogue of cladribine in human leukemic cells.
Lotfi K; Månsson E; Spasokoukotskaja T; Pettersson B; Liliemark J; Peterson C; Eriksson S; Albertioni F
Clin Cancer Res; 1999 Sep; 5(9):2438-44. PubMed ID: 10499616
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
