212 related articles for article (PubMed ID: 7541711)
1. Activity of a single-chain immunotoxin that selectively kills lymphoma and other B-lineage cells expressing the CD40 antigen.
Francisco JA; Gilliland LK; Stebbins MR; Norris NA; Ledbetter JA; Siegall CB
Cancer Res; 1995 Jul; 55(14):3099-104. PubMed ID: 7541711
[TBL] [Abstract][Full Text] [Related]
2. Cytokine activation sensitizes human monocytic and endothelial cells to the cytotoxic effects of an anti-CD40 immunotoxin.
Francisco JA; Kiener PA; Moran-Davis P; Ledbetter JA; Siegall CB
J Immunol; 1996 Aug; 157(4):1652-8. PubMed ID: 8759752
[TBL] [Abstract][Full Text] [Related]
3. Complete regression of human B-cell lymphoma xenografts in mice treated with recombinant anti-CD22 immunotoxin RFB4(dsFv)-PE38 at doses tolerated by cynomolgus monkeys.
Kreitman RJ; Wang QC; FitzGerald DJ; Pastan I
Int J Cancer; 1999 Mar; 81(1):148-55. PubMed ID: 10077166
[TBL] [Abstract][Full Text] [Related]
4. Recombinant immunotoxins containing the VH or VL domain of monoclonal antibody B3 fused to Pseudomonas exotoxin.
Brinkmann U; Lee BK; Pastan I
J Immunol; 1993 Apr; 150(7):2774-82. PubMed ID: 8454854
[TBL] [Abstract][Full Text] [Related]
5. Construction, expression, and characterization of BD1-G28-5 sFv, a single-chain anti-CD40 immunotoxin containing the ribosome-inactivating protein bryodin 1.
Francisco JA; Gawlak SL; Siegall CB
J Biol Chem; 1997 Sep; 272(39):24165-9. PubMed ID: 9305866
[TBL] [Abstract][Full Text] [Related]
6. The recombinant immunotoxin anti-Tac(Fv)-Pseudomonas exotoxin 40 is cytotoxic toward peripheral blood malignant cells from patients with adult T-cell leukemia.
Kreitman RJ; Chaudhary VK; Waldmann T; Willingham MC; FitzGerald DJ; Pastan I
Proc Natl Acad Sci U S A; 1990 Nov; 87(21):8291-5. PubMed ID: 2236041
[TBL] [Abstract][Full Text] [Related]
7. BR96 sFv-PE40, a potent single-chain immunotoxin that selectively kills carcinoma cells.
Friedman PN; McAndrew SJ; Gawlak SL; Chace D; Trail PA; Brown JP; Siegall CB
Cancer Res; 1993 Jan; 53(2):334-9. PubMed ID: 8417827
[TBL] [Abstract][Full Text] [Related]
8. Recombinant single-chain immunotoxins against T and B cell leukemias.
Kreitman RJ; Pastan I
Leuk Lymphoma; 1994 Mar; 13(1-2):1-10. PubMed ID: 8025511
[TBL] [Abstract][Full Text] [Related]
9. Single-chain immunotoxins targeted to CD40 for the treatment of human B-lineage hematologic malignancies.
Francisco JA; Siegall CB
Leuk Lymphoma; 1998 Jul; 30(3-4):237-45. PubMed ID: 9713956
[TBL] [Abstract][Full Text] [Related]
10. Antitumor activity of the single-chain immunotoxin BR96 sFv-PE40 against established breast and lung tumor xenografts.
Friedman PN; Chace DF; Trail PA; Siegall CB
J Immunol; 1993 Apr; 150(7):3054-61. PubMed ID: 8454873
[TBL] [Abstract][Full Text] [Related]
11. Anti-Tac(Fab)-PE40, a recombinant double-chain immunotoxin which kills interleukin-2-receptor-bearing cells and induces complete remission in an in vivo tumor model.
Kreitman RJ; Chang CN; Hudson DV; Queen C; Bailon P; Pastan I
Int J Cancer; 1994 Jun; 57(6):856-64. PubMed ID: 8206679
[TBL] [Abstract][Full Text] [Related]
12. Rapid humanization of the Fv of monoclonal antibody B3 by using framework exchange of the recombinant immunotoxin B3(Fv)-PE38.
Benhar I; Padlan EA; Jung SH; Lee B; Pastan I
Proc Natl Acad Sci U S A; 1994 Dec; 91(25):12051-5. PubMed ID: 7991583
[TBL] [Abstract][Full Text] [Related]
13. In vivo efficacy and toxicity of a single-chain immunotoxin targeted to CD40.
Francisco JA; Schreiber GJ; Comereski CR; Mezza LE; Warner GL; Davidson TJ; Ledbetter JA; Siegall CB
Blood; 1997 Jun; 89(12):4493-500. PubMed ID: 9192773
[TBL] [Abstract][Full Text] [Related]
14. Targeted therapy of carcinomas using BR96 sFv-PE40, a single-chain immunotoxin that binds to the Le(y) antigen.
Siegall CB
Semin Cancer Biol; 1995 Oct; 6(5):289-95. PubMed ID: 8562906
[TBL] [Abstract][Full Text] [Related]
15. BR96 sFv-PE40 immunotoxin: nonclinical safety assessment.
Haggerty HG; Warner WA; Comereski CR; Peden WM; Mezza LE; Damle BD; Siegall CB; Davidson TJ
Toxicol Pathol; 1999; 27(1):87-94. PubMed ID: 10367679
[TBL] [Abstract][Full Text] [Related]
16. In vitro and in vivo characterization of BR96 sFv-PE40. A single-chain immunotoxin fusion protein that cures human breast carcinoma xenografts in athymic mice and rats.
Siegall CB; Chace D; Mixan B; Garrigues U; Wan H; Paul L; Wolff E; Hellström I; Hellström KE
J Immunol; 1994 Mar; 152(5):2377-84. PubMed ID: 8133048
[TBL] [Abstract][Full Text] [Related]
17. Cytotoxic and antitumor activity of a recombinant immunotoxin composed of disulfide-stabilized anti-Tac Fv fragment and truncated Pseudomonas exotoxin.
Reiter Y; Kreitman RJ; Brinkmann U; Pastan I
Int J Cancer; 1994 Jul; 58(1):142-9. PubMed ID: 8014011
[TBL] [Abstract][Full Text] [Related]
18. Temporal association of CD40 antigen expression with discrete stages of human B-cell ontogeny and the efficacy of anti-CD40 immunotoxins against clonogenic B-lineage acute lymphoblastic leukemia as well as B-lineage non-Hodgkin's lymphoma cells.
Uckun FM; Gajl-Peczalska K; Myers DE; Jaszcz W; Haissig S; Ledbetter JA
Blood; 1990 Dec; 76(12):2449-56. PubMed ID: 1702326
[TBL] [Abstract][Full Text] [Related]
19. Cytotoxicity of recombinant Fab and Fv immunotoxins on adult T-cell leukemia lymph node and blood cells in the presence of soluble interleukin-2 receptor.
Saito T; Kreitman RJ; Hanada S; Makino T; Utsunomiya A; Sumizawa T; Arima T; Chang CN; Hudson D; Pastan I
Cancer Res; 1994 Feb; 54(4):1059-64. PubMed ID: 8313362
[TBL] [Abstract][Full Text] [Related]
20. Single-chain immunotoxins directed at the human transferrin receptor containing Pseudomonas exotoxin A or diphtheria toxin: anti-TFR(Fv)-PE40 and DT388-anti-TFR(Fv).
Batra JK; Fitzgerald DJ; Chaudhary VK; Pastan I
Mol Cell Biol; 1991 Apr; 11(4):2200-5. PubMed ID: 2005905
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]