BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1256 related articles for article (PubMed ID: 7542991)

  • 1. A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides.
    van der Geer P; Wiley S; Lai VK; Olivier JP; Gish GD; Stephens R; Kaplan D; Shoelson S; Pawson T
    Curr Biol; 1995 Apr; 5(4):404-12. PubMed ID: 7542991
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Shc binding to nerve growth factor receptor is mediated by the phosphotyrosine interaction domain.
    Dikic I; Batzer AG; Blaikie P; Obermeier A; Ullrich A; Schlessinger J; Margolis B
    J Biol Chem; 1995 Jun; 270(25):15125-9. PubMed ID: 7541035
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein-protein interactions.
    van der Geer P; Wiley S; Gish GD; Pawson T
    Curr Biol; 1996 Nov; 6(11):1435-44. PubMed ID: 8939605
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A mammalian adaptor protein with conserved Src homology 2 and phosphotyrosine-binding domains is related to Shc and is specifically expressed in the brain.
    O'Bryan JP; Songyang Z; Cantley L; Der CJ; Pawson T
    Proc Natl Acad Sci U S A; 1996 Apr; 93(7):2729-34. PubMed ID: 8610109
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of residues that control specific binding of the Shc phosphotyrosine-binding domain to phosphotyrosine sites.
    van der Geer P; Wiley S; Gish GD; Lai VK; Stephens R; White MF; Kaplan D; Pawson T
    Proc Natl Acad Sci U S A; 1996 Feb; 93(3):963-8. PubMed ID: 8577769
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Shc phosphotyrosine-binding domain dominantly interacts with epidermal growth factor receptors and mediates Ras activation in intact cells.
    Sakaguchi K; Okabayashi Y; Kido Y; Kimura S; Matsumura Y; Inushima K; Kasuga M
    Mol Endocrinol; 1998 Apr; 12(4):536-43. PubMed ID: 9544989
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional importance of amino-terminal domain of Shc for interaction with insulin and epidermal growth factor receptors in phosphorylation-independent manner.
    Sasaoka T; Ishihara H; Sawa T; Ishiki M; Morioka H; Imamura T; Usui I; Takata Y; Kobayashi M
    J Biol Chem; 1996 Aug; 271(33):20082-7. PubMed ID: 8702728
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The phosphotyrosine interaction domain of Shc binds an LXNPXY motif on the epidermal growth factor receptor.
    Batzer AG; Blaikie P; Nelson K; Schlessinger J; Margolis B
    Mol Cell Biol; 1995 Aug; 15(8):4403-9. PubMed ID: 7542744
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The role of the Shc phosphotyrosine interaction/phosphotyrosine binding domain and tyrosine phosphorylation sites in polyoma middle T antigen-mediated cell transformation.
    Blaikie PA; Fournier E; Dilworth SM; Birnbaum D; Borg JP; Margolis B
    J Biol Chem; 1997 Aug; 272(33):20671-7. PubMed ID: 9252386
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A Drosophila shc gene product is implicated in signaling by the DER receptor tyrosine kinase.
    Lai KM; Olivier JP; Gish GD; Henkemeyer M; McGlade J; Pawson T
    Mol Cell Biol; 1995 Sep; 15(9):4810-8. PubMed ID: 7651398
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of residues within the SHC phosphotyrosine binding/phosphotyrosine interaction domain crucial for phosphopeptide interaction.
    Yajnik V; Blaikie P; Bork P; Margolis B
    J Biol Chem; 1996 Jan; 271(4):1813-6. PubMed ID: 8567619
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The src homology 2 and phosphotyrosine binding domains of the ShcC adaptor protein function as inhibitors of mitogenic signaling by the epidermal growth factor receptor.
    O'Bryan JP; Lambert QT; Der CJ
    J Biol Chem; 1998 Aug; 273(32):20431-7. PubMed ID: 9685397
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine-phosphorylated Shc.
    Liu SK; McGlade CJ
    Oncogene; 1998 Dec; 17(24):3073-82. PubMed ID: 9872323
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A region in Shc distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors.
    Blaikie P; Immanuel D; Wu J; Li N; Yajnik V; Margolis B
    J Biol Chem; 1994 Dec; 269(51):32031-4. PubMed ID: 7798194
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Binding of Shc to the NPXY motif is mediated by its N-terminal domain.
    Prigent SA; Pillay TS; Ravichandran KS; Gullick WJ
    J Biol Chem; 1995 Sep; 270(38):22097-100. PubMed ID: 7673183
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Direct interaction between Shc and the platelet-derived growth factor beta-receptor.
    Yokote K; Mori S; Hansen K; McGlade J; Pawson T; Heldin CH; Claesson-Welsh L
    J Biol Chem; 1994 May; 269(21):15337-43. PubMed ID: 8195171
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Interaction of Shc with Grb2 regulates association of Grb2 with mSOS.
    Ravichandran KS; Lorenz U; Shoelson SE; Burakoff SJ
    Mol Cell Biol; 1995 Feb; 15(2):593-600. PubMed ID: 7529871
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel mode of ligand binding by the SH2 domain of the human XLP disease gene product SAP/SH2D1A.
    Li SC; Gish G; Yang D; Coffey AJ; Forman-Kay JD; Ernberg I; Kay LE; Pawson T
    Curr Biol; 1999 Dec; 9(23):1355-62. PubMed ID: 10607564
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Tyrosines 1148 and 1173 of activated human epidermal growth factor receptors are binding sites of Shc in intact cells.
    Okabayashi Y; Kido Y; Okutani T; Sugimoto Y; Sakaguchi K; Kasuga M
    J Biol Chem; 1994 Jul; 269(28):18674-8. PubMed ID: 8034616
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Formation of Shc-Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins.
    Salcini AE; McGlade J; Pelicci G; Nicoletti I; Pawson T; Pelicci PG
    Oncogene; 1994 Oct; 9(10):2827-36. PubMed ID: 8084588
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 63.