These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

402 related articles for article (PubMed ID: 7543369)

  • 1. X-ray structure of calcineurin inhibited by the immunophilin-immunosuppressant FKBP12-FK506 complex.
    Griffith JP; Kim JL; Kim EE; Sintchak MD; Thomson JA; Fitzgibbon MJ; Fleming MA; Caron PR; Hsiao K; Navia MA
    Cell; 1995 Aug; 82(3):507-22. PubMed ID: 7543369
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Calcineurin-immunosuppressor complexes.
    Stoddard BL; Flick KE
    Curr Opin Struct Biol; 1996 Dec; 6(6):770-5. PubMed ID: 8994877
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structures of human calcineurin and the human FKBP12-FK506-calcineurin complex.
    Kissinger CR; Parge HE; Knighton DR; Lewis CT; Pelletier LA; Tempczyk A; Kalish VJ; Tucker KD; Showalter RE; Moomaw EW
    Nature; 1995 Dec; 378(6557):641-4. PubMed ID: 8524402
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Modeling the interaction between FK506 and FKBP12: a mechanism for formation of the calcineurin inhibitory complex.
    Ivery MT; Weiler L
    Bioorg Med Chem; 1997 Feb; 5(2):217-32. PubMed ID: 9061187
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Charged surface residues of FKBP12 participate in formation of the FKBP12-FK506-calcineurin complex.
    Aldape RA; Futer O; DeCenzo MT; Jarrett BP; Murcko MA; Livingston DJ
    J Biol Chem; 1992 Aug; 267(23):16029-32. PubMed ID: 1379588
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Structure comparison of native and mutant human recombinant FKBP12 complexes with the immunosuppressant drug FK506 (tacrolimus).
    Itoh S; Navia MA
    Protein Sci; 1995 Nov; 4(11):2261-8. PubMed ID: 8563622
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FK506 binding protein mutational analysis. Defining the surface residue contributions to stability of the calcineurin co-complex.
    Futer O; DeCenzo MT; Aldape RA; Livingston DJ
    J Biol Chem; 1995 Aug; 270(32):18935-40. PubMed ID: 7642551
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Improved calcineurin inhibition by yeast FKBP12-drug complexes. Crystallographic and functional analysis.
    Rotonda J; Burbaum JJ; Chan HK; Marcy AI; Becker JW
    J Biol Chem; 1993 Apr; 268(11):7607-9. PubMed ID: 7681823
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interaction of tacrolimus(FK506) and its metabolites with FKBP and calcineurin.
    Tamura K; Fujimura T; Iwasaki K; Sakuma S; Fujitsu T; Nakamura K; Shimomura K; Kuno T; Tanaka C; Kobayashi M
    Biochem Biophys Res Commun; 1994 Jul; 202(1):437-43. PubMed ID: 7518678
    [TBL] [Abstract][Full Text] [Related]  

  • 10. FKBP12-FK506 complex inhibits phosphatase activity of two mammalian isoforms of calcineurin irrespective of their substrates or activation mechanisms.
    Mukai H; Kuno T; Chang CD; Lane B; Luly JR; Tanaka C
    J Biochem; 1993 Mar; 113(3):292-8. PubMed ID: 7683641
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dynamic NMR studies of ligand-receptor interactions: design and analysis of a rapidly exchanging complex of FKBP-12/FK506 with a 24 kDa calcineurin fragment.
    Fejzo J; Lepre CA; Peng JW; Su MS; Thomson JA; Moore JM
    Protein Sci; 1996 Sep; 5(9):1917-21. PubMed ID: 8880916
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targets of immunophilin-immunosuppressant complexes are distinct highly conserved regions of calcineurin A.
    Cardenas ME; Muir RS; Breuder T; Heitman J
    EMBO J; 1995 Jun; 14(12):2772-83. PubMed ID: 7540976
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The complex of FK506-binding protein 12 and FK506 inhibits calcineurin phosphatase activity and IgE activation-induced cytokine transcripts, but not exocytosis, in mouse mast cells.
    Fruman DA; Bierer BE; Benes JE; Burakoff SJ; Austen KF; Katz HR
    J Immunol; 1995 Feb; 154(4):1846-51. PubMed ID: 7530743
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A novel FK506 binding protein can mediate the immunosuppressive effects of FK506 and is associated with the cardiac ryanodine receptor.
    Lam E; Martin MM; Timerman AP; Sabers C; Fleischer S; Lukas T; Abraham RT; O'Keefe SJ; O'Neill EA; Wiederrecht GJ
    J Biol Chem; 1995 Nov; 270(44):26511-22. PubMed ID: 7592869
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux.
    Cameron AM; Steiner JP; Roskams AJ; Ali SM; Ronnett GV; Snyder SH
    Cell; 1995 Nov; 83(3):463-72. PubMed ID: 8521476
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mean field analysis of FKBP12 complexes with FK506 and rapamycin: implications for a role of crystallographic water molecules in molecular recognition and specificity.
    Rejto PA; Verkhivker GM
    Proteins; 1997 Jul; 28(3):313-24. PubMed ID: 9223178
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Rabbit FKBP-59/HBI does not inhibit calcineurin activity in vitro.
    Lebeau MC; Myagkikh I; Rouvière-Fourmy N; Baulieu EE; Klee CB
    Biochem Biophys Res Commun; 1994 Sep; 203(2):750-5. PubMed ID: 7522447
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Control of a novel adenylyl cyclase by calcineurin.
    Paterson JM; Smith SM; Harmar AJ; Antoni FA
    Biochem Biophys Res Commun; 1995 Sep; 214(3):1000-8. PubMed ID: 7575502
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Three-dimensional structure and actions of immunosuppressants and their immunophilins.
    Braun W; Kallen J; Mikol V; Walkinshaw MD; Wüthrich K
    FASEB J; 1995 Jan; 9(1):63-72. PubMed ID: 7529736
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interaction of FKBP12-FK506 with calcineurin A at the B subunit-binding domain.
    Kawamura A; Su MS
    J Biol Chem; 1995 Jun; 270(26):15463-6. PubMed ID: 7541044
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 21.