These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 7547912)

  • 1. Tryptophan fluorescence of human phenylalanine hydroxylase produced in Escherichia coli.
    Knappskog PM; Haavik J
    Biochemistry; 1995 Sep; 34(37):11790-9. PubMed ID: 7547912
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A comparison of kinetic and regulatory properties of the tetrameric and dimeric forms of wild-type and Thr427-->Pro mutant human phenylalanine hydroxylase: contribution of the flexible hinge region Asp425-Gln429 to the tetramerization and cooperative substrate binding.
    Bjørgo E; de Carvalho RM; Flatmark T
    Eur J Biochem; 2001 Feb; 268(4):997-1005. PubMed ID: 11179966
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Expression of recombinant human phenylalanine hydroxylase as fusion protein in Escherichia coli circumvents proteolytic degradation by host cell proteases. Isolation and characterization of the wild-type enzyme.
    Martinez A; Knappskog PM; Olafsdottir S; Døskeland AP; Eiken HG; Svebak RM; Bozzini M; Apold J; Flatmark T
    Biochem J; 1995 Mar; 306 ( Pt 2)(Pt 2):589-97. PubMed ID: 7887915
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure/function relationships in human phenylalanine hydroxylase. Effect of terminal deletions on the oligomerization, activation and cooperativity of substrate binding to the enzyme.
    Knappskog PM; Flatmark T; Aarden JM; Haavik J; Martínez A
    Eur J Biochem; 1996 Dec; 242(3):813-21. PubMed ID: 9022714
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Recombinant human phenylalanine hydroxylase: novel regulatory and structural properties.
    Kowlessur D; Citron BA; Kaufman S
    Arch Biochem Biophys; 1996 Sep; 333(1):85-95. PubMed ID: 8806757
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Substrate-induced conformational transition in human phenylalanine hydroxylase as studied by surface plasmon resonance analyses: the effect of terminal deletions, substrate analogues and phosphorylation.
    Stokka AJ; Flatmark T
    Biochem J; 2003 Feb; 369(Pt 3):509-18. PubMed ID: 12379147
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A fluorescence study of single tryptophan-containing mutants of enzyme IImtl of the Escherichia coli phosphoenolpyruvate-dependent mannitol transport system.
    Dijkstra DS; Broos J; Lolkema JS; Enequist H; Minke W; Robillard GT
    Biochemistry; 1996 May; 35(21):6628-34. PubMed ID: 8639611
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Characterization of chimeric pterin-dependent hydroxylases: contributions of the regulatory domains of tyrosine and phenylalanine hydroxylase to substrate specificity.
    Daubner SC; Hillas PJ; Fitzpatrick PF
    Biochemistry; 1997 Sep; 36(39):11574-82. PubMed ID: 9305947
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Steady-state kinetics and tryptophan fluorescence properties of halohydrin dehalogenase from Agrobacterium radiobacter. Roles of W139 and W249 in the active site and halide-induced conformational change.
    Tang L; van Merode AE; Lutje Spelberg JH; Fraaije MW; Janssen DB
    Biochemistry; 2003 Dec; 42(47):14057-65. PubMed ID: 14636074
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Circular dichroism and fluorescence spectroscopic properties of the major core protein of feline immunodeficiency virus and its tryptophan mutants. Assignment of the individual contribution of the aromatic sidechains.
    Yélamos B; Núñez E; Gómez-Gutiérrez J; Datta M; Pacheco B; Peterson DL; Gavilanes F
    Eur J Biochem; 1999 Dec; 266(3):1081-9. PubMed ID: 10583405
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhancement of L-tryptophan 5-hydroxylation activity by structure-based modification of L-phenylalanine 4-hydroxylase from Chromobacterium violaceum.
    Kino K; Hara R; Nozawa A
    J Biosci Bioeng; 2009 Sep; 108(3):184-9. PubMed ID: 19664549
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A fluorescence study of Tn10-encoded tet repressor.
    Wasylewski Z; Kaszycki P; Drwiega M
    J Protein Chem; 1996 Jan; 15(1):45-58. PubMed ID: 8838589
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of mutations at Cys237 on the activation state and activity of human phenylalanine hydroxylase.
    Knappskog PM; Martínez A
    FEBS Lett; 1997 Jun; 409(1):7-11. PubMed ID: 9199493
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphorylation of recombinant human phenylalanine hydroxylase: effect on catalytic activity, substrate activation and protection against non-specific cleavage of the fusion protein by restriction protease.
    Døskeland AP; Martinez A; Knappskog PM; Flatmark T
    Biochem J; 1996 Jan; 313 ( Pt 2)(Pt 2):409-14. PubMed ID: 8573072
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Probing the role of crystallographically defined/predicted hinge-bending regions in the substrate-induced global conformational transition and catalytic activation of human phenylalanine hydroxylase by single-site mutagenesis.
    Stokka AJ; Carvalho RN; Barroso JF; Flatmark T
    J Biol Chem; 2004 Jun; 279(25):26571-80. PubMed ID: 15060071
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Partial characterization and three-dimensional-structural localization of eight mutations in exon 7 of the human phenylalanine hydroxylase gene associated with phenylketonuria.
    Bjørgo E; Knappskog PM; Martinez A; Stevens RC; Flatmark T
    Eur J Biochem; 1998 Oct; 257(1):1-10. PubMed ID: 9799096
    [TBL] [Abstract][Full Text] [Related]  

  • 17. PKU mutation G46S is associated with increased aggregation and degradation of the phenylalanine hydroxylase enzyme.
    Eiken HG; Knappskog PM; Apold J; Flatmark T
    Hum Mutat; 1996; 7(3):228-38. PubMed ID: 8829656
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Fluorescence of native single-Trp mutants in the lactose permease from Escherichia coli: structural properties and evidence for a substrate-induced conformational change.
    Weitzman C; Consler TG; Kaback HR
    Protein Sci; 1995 Nov; 4(11):2310-8. PubMed ID: 8563627
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nanosecond pulse fluorometry of conformational change in phenylalanine hydroxylase associated with activation.
    Koizumi S; Tanaka F; Kaneda N; Kano K; Nagatsu T
    Biochemistry; 1988 Jan; 27(2):640-6. PubMed ID: 3349052
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Unique environment of Trp48 in Pseudomonas aeruginosa azurin as probed by site-directed mutagenesis and dynamic fluorescence spectroscopy.
    Gilardi G; Mei G; Rosato N; Canters GW; Finazzi-Agrò A
    Biochemistry; 1994 Feb; 33(6):1425-32. PubMed ID: 8312262
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.