206 related articles for article (PubMed ID: 7547989)
1. Double-stranded damage of DNA.RNA hybrids by neocarzinostatin chromophore: selective C-1' chemistry on the RNA strand.
Zeng X; Xi Z; Kappen LS; Tan W; Goldberg IH
Biochemistry; 1995 Sep; 34(38):12435-44. PubMed ID: 7547989
[TBL] [Abstract][Full Text] [Related]
2. Selective abstraction of 2H from C-1' of the C residue in AGC.ICT by the radical center at C-2 of activated neocarzinostatin chromophore: structure of the drug/DNA complex responsible for bistranded lesion formation.
Meschwitz SM; Schultz RG; Ashley GW; Goldberg IH
Biochemistry; 1992 Sep; 31(38):9117-21. PubMed ID: 1390698
[TBL] [Abstract][Full Text] [Related]
3. Characterization of a novel covalent monoadduct on the RNA overhang of an RNA-DNA hybrid induced by antitumor antibiotic neocarzinostatin.
Zheng P; Liu CL; Xi Z; Smith RD; Goldberg IH
Biochemistry; 1998 Feb; 37(6):1706-13. PubMed ID: 9484242
[TBL] [Abstract][Full Text] [Related]
4. DNA damage by thiol-activated neocarzinostatin chromophore at bulged sites.
Gu F; Xi Z; Goldberg IH
Biochemistry; 2000 Apr; 39(16):4881-91. PubMed ID: 10769146
[TBL] [Abstract][Full Text] [Related]
5. Exclusive production of bistranded DNA damage by calicheamicin.
Dedon PC; Salzberg AA; Xu J
Biochemistry; 1993 Apr; 32(14):3617-22. PubMed ID: 8466904
[TBL] [Abstract][Full Text] [Related]
6. Probing DNA single strands for single-base bulges with neocarzinostatin chromophore.
Kappen LS; Xi Z; Goldberg IH
Biochemistry; 2001 Dec; 40(50):15378-83. PubMed ID: 11735421
[TBL] [Abstract][Full Text] [Related]
7. Selective abstraction of 2H from C-5' of thymidylate in an oligodeoxynucleotide by the radical center at C-6 of the diradical species of neocarzinostatin: chemical evidence for the structure of the activated drug-DNA complex.
Meschwitz SM; Goldberg IH
Proc Natl Acad Sci U S A; 1991 Apr; 88(8):3047-51. PubMed ID: 1826561
[TBL] [Abstract][Full Text] [Related]
8. Atypical abasic sites generated by neocarzinostatin at sequence-specific cytidylate residues in oligodeoxynucleotides.
Kappen LS; Chen CQ; Goldberg IH
Biochemistry; 1988 Jun; 27(12):4331-40. PubMed ID: 2458753
[TBL] [Abstract][Full Text] [Related]
9. A single binding mode of activated enediyne C1027 generates two types of double-strand DNA lesions: deuterium isotope-induced shuttling between adjacent nucleotide target sites.
Xu YJ; Xi Z; Zhen YS; Goldberg IH
Biochemistry; 1995 Sep; 34(38):12451-60. PubMed ID: 7547991
[TBL] [Abstract][Full Text] [Related]
10. Neocarzinostatin-mediated DNA damage in a model AGT.ACT site: mechanistic studies of thiol-sensitive partitioning of C4' DNA damage products.
Dedon PC; Jiang ZW; Goldberg IH
Biochemistry; 1992 Feb; 31(7):1917-27. PubMed ID: 1531616
[TBL] [Abstract][Full Text] [Related]
11. Sequence-specific double-strand breakage of DNA by neocarzinostatin involves different chemical mechanisms within a staggered cleavage site.
Dedon PC; Goldberg IH
J Biol Chem; 1990 Sep; 265(25):14713-6. PubMed ID: 2144279
[TBL] [Abstract][Full Text] [Related]
12. Bulge-specific cleavage in transactivation response region RNA and its DNA analogue by neocarzinostatin chromophore.
Kappen LS; Goldberg IH
Biochemistry; 1995 May; 34(17):5997-6002. PubMed ID: 7537097
[TBL] [Abstract][Full Text] [Related]
13. Neocarzinostatin acts as a sensitive probe of DNA microheterogeneity: switching of chemistry from C-1' to C-4' by a G.T mismatch 5' to the site of DNA damage.
Kappen LS; Goldberg IH
Proc Natl Acad Sci U S A; 1992 Aug; 89(15):6706-10. PubMed ID: 1386670
[TBL] [Abstract][Full Text] [Related]
14. New complex of post-activated neocarzinostatin chromophore with DNA: bulge DNA binding from the minor groove.
Kwon Y; Xi Z; Kappen LS; Goldberg IH; Gao X
Biochemistry; 2003 Feb; 42(5):1186-98. PubMed ID: 12564921
[TBL] [Abstract][Full Text] [Related]
15. Characterization of a covalent monoadduct of neocarzinostatin chromophore at a DNA bulge.
Kappen LS; Goldberg IH
Biochemistry; 1997 Dec; 36(48):14861-7. PubMed ID: 9398208
[TBL] [Abstract][Full Text] [Related]
16. Enediyne-mediated cleavage of RNA.
Battigello JM; Cui M; Roshong S; Carter BJ
Bioorg Med Chem; 1995 Jun; 3(6):839-49. PubMed ID: 7582960
[TBL] [Abstract][Full Text] [Related]
17. Binding and cleavage characteristics of the complexes formed between the neocarzinostatin chromophore and single site containing oligonucleotides.
Stassinopoulos A; Goldberg IH
Bioorg Med Chem; 1995 Jun; 3(6):713-21. PubMed ID: 7582949
[TBL] [Abstract][Full Text] [Related]
18. Molecular models of neocarzinostatin damage of DNA: analysis of sequence dependence in 5'GAGCG:5'CGCTC.
Galat A; Goldberg IH
Nucleic Acids Res; 1990 Apr; 18(8):2093-9. PubMed ID: 2139934
[TBL] [Abstract][Full Text] [Related]
19. C1027 chromophore, a potent new enediyne antitumor antibiotic, induces sequence-specific double-strand DNA cleavage.
Xu YJ; Zhen YS; Goldberg IH
Biochemistry; 1994 May; 33(19):5947-54. PubMed ID: 8180224
[TBL] [Abstract][Full Text] [Related]
20. Deoxyribonucleic acid damage by neocarzinostatin chromophore: strand breaks generated by selective oxidation of C-5' of deoxyribose.
Kappen LS; Goldberg IH
Biochemistry; 1983 Oct; 22(21):4872-8. PubMed ID: 6227335
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
