BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

195 related articles for article (PubMed ID: 7548062)

  • 1. Sequence specificity of alkylation for a series of nitrogen mustard-containing analogues of distamycin of increasing binding site size: evidence for increased cytotoxicity with enhanced sequence specificity.
    Wyatt MD; Lee M; Garbiras BJ; Souhami RL; Hartley JA
    Biochemistry; 1995 Oct; 34(40):13034-41. PubMed ID: 7548062
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The sequence specificity of alkylation for a series of benzoic acid mustard and imidazole-containing distamycin analogues: the importance of local sequence conformation.
    Wyatt MD; Lee M; Hartley JA
    Nucleic Acids Res; 1997 Jun; 25(12):2359-64. PubMed ID: 9171086
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The role of base excision repair in the repair of DNA adducts formed by a series of nitrogen mustard-containing analogues of distamycin of increasing binding site size.
    Brooks N; McHugh PJ; Lee M; Hartley JA
    Anticancer Drug Des; 1999 Feb; 14(1):11-8. PubMed ID: 10363024
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Alkylation specificity for a series of distamycin analogues that tether chlorambucil.
    Wyatt MD; Lee M; Hartley JA
    Anticancer Drug Des; 1997 Jan; 12(1):49-60. PubMed ID: 9051113
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structure-activity relationship of a series of nitrogen mustard- and pyrrole-containing minor groove-binding agents related to distamycin.
    Wyatt MD; Garbiras BJ; Haskell MK; Lee M; Souhami RL; Hartley JA
    Anticancer Drug Des; 1994 Dec; 9(6):511-25. PubMed ID: 7880376
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA sequence-specific adenine alkylation by the novel antitumor drug tallimustine (FCE 24517), a benzoyl nitrogen mustard derivative of distamycin.
    Broggini M; Coley HM; Mongelli N; Pesenti E; Wyatt MD; Hartley JA; D'Incalci M
    Nucleic Acids Res; 1995 Jan; 23(1):81-7. PubMed ID: 7870593
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Combinatorial identification of a novel consensus sequence for the covalent DNA-binding polyamide tallimustine.
    Sunavala-Dossabhoy G; Van Dyke MW
    Biochemistry; 2005 Feb; 44(7):2510-22. PubMed ID: 15709763
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sequence-specific DNA alkylation of novel tallimustine derivatives.
    Marchini S; Cozzi P; Beria I; Geroni C; Capolongo L; D'Incalci M; Broggini M
    Anticancer Drug Des; 1998 Apr; 13(3):193-205. PubMed ID: 9595033
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Alteration in the choice of DNA repair pathway with increasing sequence selective DNA alkylation in the minor groove.
    Brooks N; McHugh PJ; Lee M; Hartley JA
    Chem Biol; 2000 Sep; 7(9):659-68. PubMed ID: 10980446
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA minor groove targeted alkylating agents based on bisbenzimidazole carriers: synthesis, cytotoxicity and sequence-specificity of DNA alkylation.
    Smaill JB; Fan JY; Denny WA
    Anticancer Drug Des; 1998 Dec; 13(8):857-80. PubMed ID: 10335264
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A New Cross-Link for an Old Cross-Linking Drug: The Nitrogen Mustard Anticancer Agent Mechlorethamine Generates Cross-Links Derived from Abasic Sites in Addition to the Expected Drug-Bridged Cross-Links.
    Nejad MI; Johnson KM; Price NE; Gates KS
    Biochemistry; 2016 Dec; 55(50):7033-7041. PubMed ID: 27992994
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Novel DNA-directed alkylating agents consisting of naphthalimide, nitrogen mustard and lexitropsin moieties: synthesis, DNA sequence specificity and biological evaluation.
    Gupta R; Liu J; Xie G; Lown JW
    Anticancer Drug Des; 1996 Dec; 11(8):581-96. PubMed ID: 9022747
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The effects of a benzoic acid mustard derivative of distamycin A (FCE 24517) and related minor groove-binding distamycin analogues on the activity of major groove-binding alkylating agents.
    Coley HM; Mongelli N; D'Incalci M
    Biochem Pharmacol; 1993 Feb; 45(3):619-26. PubMed ID: 8442762
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Polybenzamide mustards: structure-activity relationships for DNA sequence-specific alkylation.
    Turner PR; Ferguson LR; Denny WA
    Anticancer Drug Des; 1999 Feb; 14(1):61-70. PubMed ID: 10363028
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Structure-activity relationship of a series of C-terminus modified aminoalkyl, diaminoalkyl- and anilino-containing analogues of the benzoic acid mustard distamycin derivative tallimustine: synthesis, DNA binding and cytotoxicity studies.
    Brooks N; Hartley JA; Simpson JE; Wright SR; Woo S; Centioni S; Fontaine MD; McIntyre TE; Lee M
    Bioorg Med Chem; 1997 Aug; 5(8):1497-507. PubMed ID: 9313856
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNA sequence selectivity of guanine-N7 alkylation by nitrogen mustards.
    Mattes WB; Hartley JA; Kohn KW
    Nucleic Acids Res; 1986 Apr; 14(7):2971-87. PubMed ID: 3960738
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Benzoyl and cinnamoyl nitrogen mustard derivatives of benzoheterocyclic analogues of the tallimustine: synthesis and antitumour activity.
    Baraldi PG; Romagnoli R; Giovanna Pavani M; del Carmen Nunez M; Bingham JP; Hartley JA
    Bioorg Med Chem; 2002 May; 10(5):1611-8. PubMed ID: 11886822
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthesis, DNA binding, cytotoxicity and sequence specificity of a series of imidazole-containing analogs of the benzoic acid mustard distamycin derivative tallimustine containing an alkylating group at the C-terminus.
    Brooks N; Lee M; Wright SR; Woo S; Centioni S; Hartley JA
    Anticancer Drug Des; 1997 Oct; 12(7):591-606. PubMed ID: 9365504
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Effect of ionic strength and cationic DNA affinity binders on the DNA sequence selective alkylation of guanine N7-positions by nitrogen mustards.
    Hartley JA; Forrow SM; Souhami RL
    Biochemistry; 1990 Mar; 29(12):2985-91. PubMed ID: 2337578
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Tallimustine lesions in cellular DNA are AT sequence-specific but not region-specific.
    Herzig MC; Trevino AV; Arnett B; Woynarowski JM
    Biochemistry; 1999 Oct; 38(42):14045-55. PubMed ID: 10529251
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.