These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 7548749)

  • 61. Metabolic fate of valproic acid in the rhesus monkey. Formation of a toxic metabolite, 2-n-propyl-4-pentenoic acid.
    Rettenmeier AW; Gordon WP; Prickett KS; Levy RH; Lockard JS; Thummel KE; Baillie TA
    Drug Metab Dispos; 1986; 14(4):443-53. PubMed ID: 2873992
    [TBL] [Abstract][Full Text] [Related]  

  • 62. P450-catalyzed in-chain desaturation of valproic acid: isoform selectivity and mechanism of formation of Delta 3-valproic acid generated by baculovirus-expressed CYP3A1.
    Fisher MB; Thompson SJ; Ribeiro V; Lechner MC; Rettie AE
    Arch Biochem Biophys; 1998 Aug; 356(1):63-70. PubMed ID: 9681992
    [TBL] [Abstract][Full Text] [Related]  

  • 63. Evaluation of in situ generated valproyl 1-O-β-acyl glucuronide in valproic acid toxicity in sandwich-cultured rat hepatocytes.
    Surendradoss J; Chang TK; Abbott FS
    Drug Metab Dispos; 2014 Nov; 42(11):1834-42. PubMed ID: 25147275
    [TBL] [Abstract][Full Text] [Related]  

  • 64. Association of valproic acid and 2-propyl-4-pentenoic acid concentrations with adverse reaction in 254 Chinese patients with epilepsy.
    Ma H; Zhu W; Wang C; Pan J; Yang X; Luo J; Wang P
    Zhong Nan Da Xue Xue Bao Yi Xue Ban; 2019 Jul; 44(7):775-783. PubMed ID: 31413215
    [TBL] [Abstract][Full Text] [Related]  

  • 65. Stereochemical studies on the beta-oxidation of valproic acid in isolated rat hepatocytes.
    Shirley MA; Hu P; Baillie TA
    Drug Metab Dispos; 1993; 21(4):580-6. PubMed ID: 8104116
    [TBL] [Abstract][Full Text] [Related]  

  • 66. Simultaneous determination of valproic acid and 2-propyl-4-pentenoic acid for the prediction of clinical adverse effects in Chinese patients with epilepsy.
    Chen ZJ; Wang XD; Wang HS; Chen SD; Zhou LM; Li JL; Shu WY; Zhou JQ; Fang ZY; Zhang Y; Huang M
    Seizure; 2012 Mar; 21(2):110-7. PubMed ID: 22055352
    [TBL] [Abstract][Full Text] [Related]  

  • 67. Valproic acid induced liver injury: An insight into molecular toxicological mechanism.
    Ezhilarasan D; Mani U
    Environ Toxicol Pharmacol; 2022 Oct; 95():103967. PubMed ID: 36058508
    [TBL] [Abstract][Full Text] [Related]  

  • 68. A postulated role of garlic organosulfur compounds in prevention of valproic acid hepatotoxicity.
    Sabayan B; Foroughinia F; Chohedry A
    Med Hypotheses; 2007; 68(3):512-4. PubMed ID: 17046167
    [TBL] [Abstract][Full Text] [Related]  

  • 69. Asymmetric synthesis and enantioselective teratogenicity of 2-n-propyl-4-pentenoic acid (4-en-VPA), an active metabolite of the anticonvulsant drug, valproic acid.
    Hauck RS; Nau H
    Toxicol Lett; 1989 Oct; 49(1):41-8. PubMed ID: 2510370
    [TBL] [Abstract][Full Text] [Related]  

  • 70. Hepatotoxicity in rat following administration of valproic acid.
    Sugimoto T; Woo M; Nishida N; Takeuchi T; Sakane Y; Kobayashi Y
    Epilepsia; 1987; 28(2):142-6. PubMed ID: 3102219
    [TBL] [Abstract][Full Text] [Related]  

  • 71. The valproic acid metabolite E-2-n-propyl-2-pentenoic acid does not induce spina bifida in the mouse.
    Ehlers K; Stürje H; Merker HJ; Nau H
    Dev Pharmacol Ther; 1992; 19(4):196-204. PubMed ID: 1343622
    [TBL] [Abstract][Full Text] [Related]  

  • 72. Age-related differences in susceptibility to toxic effects of valproic acid in rats.
    Espandiari P; Zhang J; Schnackenberg LK; Miller TJ; Knapton A; Herman EH; Beger RD; Hanig JP
    J Appl Toxicol; 2008 Jul; 28(5):628-37. PubMed ID: 17994530
    [TBL] [Abstract][Full Text] [Related]  

  • 73. Valnoctamide, valpromide and valnoctic acid are much less teratogenic in mice than valproic acid.
    Radatz M; Ehlers K; Yagen B; Bialer M; Nau H
    Epilepsy Res; 1998 Mar; 30(1):41-8. PubMed ID: 9551843
    [TBL] [Abstract][Full Text] [Related]  

  • 74. Obeticholic Acid Ameliorates Valproic Acid-Induced Hepatic Steatosis and Oxidative Stress.
    Gai Z; Krajnc E; Samodelov SL; Visentin M; Kullak-Ublick GA
    Mol Pharmacol; 2020 May; 97(5):314-323. PubMed ID: 32098797
    [TBL] [Abstract][Full Text] [Related]  

  • 75. Effects of valproic acid, some of its metabolites and analogues on prenatal development of rats in vitro and comparison with effects in vivo.
    Klug S; Lewandowski C; Zappel F; Merker HJ; Nau H; Neubert D
    Arch Toxicol; 1990; 64(7):545-53. PubMed ID: 2073128
    [TBL] [Abstract][Full Text] [Related]  

  • 76. Mitochondrial Liver Toxicity of Valproic Acid and Its Acid Derivatives Is Related to Inhibition of α-Lipoamide Dehydrogenase.
    Kudin AP; Mawasi H; Eisenkraft A; Elger CE; Bialer M; Kunz WS
    Int J Mol Sci; 2017 Sep; 18(9):. PubMed ID: 28878165
    [TBL] [Abstract][Full Text] [Related]  

  • 77. Complete beta-oxidation of valproate: cleavage of 3-oxovalproyl-CoA by a mitochondrial 3-oxoacyl-CoA thiolase.
    Silva MF; Ruiter JP; Overmars H; Bootsma AH; van Gennip AH; Jakobs C; Duran M; Tavares de Almeida I; Wanders RJ
    Biochem J; 2002 Mar; 362(Pt 3):755-60. PubMed ID: 11879205
    [TBL] [Abstract][Full Text] [Related]  

  • 78. Determination of valproic acid and its metabolites using gas chromatography with mass-selective detection: application to serum and urine samples from sheep.
    Yu D; Gordon JD; Zheng J; Panesar SK; Riggs KW; Rurak DW; Abbott FS
    J Chromatogr B Biomed Appl; 1995 Apr; 666(2):269-81. PubMed ID: 7633603
    [TBL] [Abstract][Full Text] [Related]  

  • 79. Valproic acid metabolism and its effects on mitochondrial fatty acid oxidation: a review.
    Silva MF; Aires CC; Luis PB; Ruiter JP; IJlst L; Duran M; Wanders RJ; Tavares de Almeida I
    J Inherit Metab Dis; 2008 Apr; 31(2):205-16. PubMed ID: 18392741
    [TBL] [Abstract][Full Text] [Related]  

  • 80. Stereoselective synthesis of the diunsaturated metabolites of valproic acid.
    Lee RD; Kassahun K; Abbott FS
    J Pharm Sci; 1989 Aug; 78(8):667-71. PubMed ID: 2506329
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 11.