266 related articles for article (PubMed ID: 7549043)
21. Synthesis of Mitomycin C and Decarbamoylmitomycin C N(2) deoxyguanosine-adducts.
Champeil E; Cheng SY; Huang BT; Conchero-Guisan M; Martinez T; Paz MM; Sapse AM
Bioorg Chem; 2016 Apr; 65():90-9. PubMed ID: 26894558
[TBL] [Abstract][Full Text] [Related]
22. Mitomycin C-DNA adducts generated by DT-diaphorase. Revised mechanism of the enzymatic reductive activation of mitomycin C.
Suresh Kumar G; Lipman R; Cummings J; Tomasz M
Biochemistry; 1997 Nov; 36(46):14128-36. PubMed ID: 9369485
[TBL] [Abstract][Full Text] [Related]
23. Preferential activation of mitomycin C to cytotoxic metabolites by hypoxic tumor cells.
Kennedy KA; Rockwell S; Sartorelli AC
Cancer Res; 1980 Jul; 40(7):2356-60. PubMed ID: 7388797
[TBL] [Abstract][Full Text] [Related]
24. Differential activation of p53 by the various adducts of mitomycin C.
Abbas T; Olivier M; Lopez J; Houser S; Xiao G; Kumar GS; Tomasz M; Bargonetti J
J Biol Chem; 2002 Oct; 277(43):40513-9. PubMed ID: 12183457
[TBL] [Abstract][Full Text] [Related]
25. DNA interstrand cross-link and free radical formation in a human multidrug-resistant cell line from mitomycin C and its analogues.
Dusre L; Rajagopalan S; Eliot HM; Covey JM; Sinha BK
Cancer Res; 1990 Feb; 50(3):648-52. PubMed ID: 2153443
[TBL] [Abstract][Full Text] [Related]
26. Role of NAD(P)H:(quinone acceptor) oxidoreductase (DT-diaphorase) in activation of mitomycin C under acidic conditions.
Begleiter A; Leith MK
Mol Pharmacol; 1993 Jul; 44(1):210-5. PubMed ID: 8341273
[TBL] [Abstract][Full Text] [Related]
27. Chinese hamster ovary cell lines resistant to mitomycin C under aerobic but not hypoxic conditions are deficient in DT-diaphorase.
Dulhanty AM; Whitmore GF
Cancer Res; 1991 Apr; 51(7):1860-5. PubMed ID: 1900739
[TBL] [Abstract][Full Text] [Related]
28. A mitomycin-N6-deoxyadenosine adduct isolated from DNA.
Palom Y; Lipman R; Musser SM; Tomasz M
Chem Res Toxicol; 1998 Mar; 11(3):203-10. PubMed ID: 9544618
[TBL] [Abstract][Full Text] [Related]
29. Synthesis of Mitomycin C and decarbamoylmitomycin C N
Zheng M; Hwang S; Snyder T; Aquilina J; Proni G; Paz MM; Pradhan P; Cheng SY; Champeil E
Bioorg Chem; 2019 Nov; 92():103280. PubMed ID: 31539740
[TBL] [Abstract][Full Text] [Related]
30. Porfiromycin as a bioreductive alkylating agent with selective toxicity to hypoxic EMT6 tumor cells in vivo and in vitro.
Keyes SR; Rockwell S; Sartorelli AC
Cancer Res; 1985 Aug; 45(8):3642-5. PubMed ID: 3926306
[TBL] [Abstract][Full Text] [Related]
31. Activity of mitomycin C for aerobic and hypoxic cells in vitro and in vivo.
Rauth AM; Mohindra JK; Tannock IF
Cancer Res; 1983 Sep; 43(9):4154-8. PubMed ID: 6409398
[TBL] [Abstract][Full Text] [Related]
32. Isolation of Chinese hamster ovary cell mutants deficient in excision repair and mitomycin C bioactivation.
Dulhanty AM; Li M; Whitmore GF
Cancer Res; 1989 Jan; 49(1):117-22. PubMed ID: 2491748
[TBL] [Abstract][Full Text] [Related]
33. pH dependence of mitomycin C-induced cross-linking activity in EMT6 tumor cells.
Kennedy KA; McGurl JD; Leondaridis L; Alabaster O
Cancer Res; 1985 Aug; 45(8):3541-7. PubMed ID: 3926302
[TBL] [Abstract][Full Text] [Related]
34. Insight Into Factors Governing Formation, Synthesis and Stereochemical Configuration of DNA Adducts Formed by Mitomycins.
Paz MM; Champeil E
Chem Rec; 2023 Jan; 23(1):e202200193. PubMed ID: 36251922
[TBL] [Abstract][Full Text] [Related]
35. Screening for genotoxicity using the DRAG assay: investigation of halogenated environmental contaminants.
Johansson F; Allkvist A; Erixon K; Malmvärn A; Nilsson R; Bergman A; Helleday T; Jenssen D
Mutat Res; 2004 Sep; 563(1):35-47. PubMed ID: 15324747
[TBL] [Abstract][Full Text] [Related]
36. Mitomycin C and decarbamoyl mitomycin C induce p53-independent p21WAF1/CIP1 activation.
Cheng SY; Seo J; Huang BT; Napolitano T; Champeil E
Int J Oncol; 2016 Nov; 49(5):1815-1824. PubMed ID: 27666201
[TBL] [Abstract][Full Text] [Related]
37. Activation of mitomycin C by NADPH:cytochrome P-450 reductase.
Bligh HF; Bartoszek A; Robson CN; Hickson ID; Kasper CB; Beggs JD; Wolf CR
Cancer Res; 1990 Dec; 50(24):7789-92. PubMed ID: 2123741
[TBL] [Abstract][Full Text] [Related]
38. Studies on the mechanism of the cytotoxic action of the mitomycin antibiotics in hypoxic and oxygenated EMT6 cells.
Sartorelli AC; Tomasz M; Rockwell S
Adv Enzyme Regul; 1993; 33():3-17. PubMed ID: 8356915
[TBL] [Abstract][Full Text] [Related]
39. NRH:quinone oxidoreductase 2 (NQO2) catalyzes metabolic activation of quinones and anti-tumor drugs.
Celli CM; Tran N; Knox R; Jaiswal AK
Biochem Pharmacol; 2006 Jul; 72(3):366-76. PubMed ID: 16765324
[TBL] [Abstract][Full Text] [Related]
40. Bioreductive metabolism of mitomycin C in EMT6 mouse mammary tumor cells: cytotoxic and non-cytotoxic pathways, leading to different types of DNA adducts. The effect of dicumarol.
Palom Y; Belcourt MF; Tang LQ; Mehta SS; Sartorelli AC; Pritsos CA; Pritsos KL; Rockwell S; Tomasz M
Biochem Pharmacol; 2001 Jun; 61(12):1517-29. PubMed ID: 11377381
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
