183 related articles for article (PubMed ID: 7554070)
1. Procarcinogen activation by cytochrome P450 3A4 and 3A5 expressed in Escherichia coli and by human liver microsomes.
Yamazaki H; Inui Y; Wrighton SA; Guengerich FP; Shimada T
Carcinogenesis; 1995 Sep; 16(9):2167-70. PubMed ID: 7554070
[TBL] [Abstract][Full Text] [Related]
2. Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1.
Shimada T; Hayes CL; Yamazaki H; Amin S; Hecht SS; Guengerich FP; Sutter TR
Cancer Res; 1996 Jul; 56(13):2979-84. PubMed ID: 8674051
[TBL] [Abstract][Full Text] [Related]
3. Characterization of microsomal cytochrome P450 enzymes involved in the oxidation of xenobiotic chemicals in human fetal liver and adult lungs.
Shimada T; Yamazaki H; Mimura M; Wakamiya N; Ueng YF; Guengerich FP; Inui Y
Drug Metab Dispos; 1996 May; 24(5):515-22. PubMed ID: 8723730
[TBL] [Abstract][Full Text] [Related]
4. Role of human cytochrome P450 3A4 and 3A5 in the metabolism of taxotere and its derivatives: enzyme specificity, interindividual distribution and metabolic contribution in human liver.
Shou M; Martinet M; Korzekwa KR; Krausz KW; Gonzalez FJ; Gelboin HV
Pharmacogenetics; 1998 Oct; 8(5):391-401. PubMed ID: 9825831
[TBL] [Abstract][Full Text] [Related]
5. Metabolic activation of polycyclic aromatic hydrocarbons and other procarcinogens by cytochromes P450 1A1 and P450 1B1 allelic variants and other human cytochromes P450 in Salmonella typhimurium NM2009.
Shimada T; Oda Y; Gillam EM; Guengerich FP; Inoue K
Drug Metab Dispos; 2001 Sep; 29(9):1176-82. PubMed ID: 11502724
[TBL] [Abstract][Full Text] [Related]
6. Expression of cytochrome P450 3A5 in Escherichia coli: effects of 5' modification, purification, spectral characterization, reconstitution conditions, and catalytic activities.
Gillam EM; Guo Z; Ueng YF; Yamazaki H; Cock I; Reilly PE; Hooper WD; Guengerich FP
Arch Biochem Biophys; 1995 Mar; 317(2):374-84. PubMed ID: 7893152
[TBL] [Abstract][Full Text] [Related]
7. Roles of different forms of cytochrome P450 in the activation of the promutagen 6-aminochrysene to genotoxic metabolites in human liver microsomes.
Yamazaki H; Mimura M; Oda Y; Inui Y; Shiraga T; Iwasaki K; Guengerich FP; Shimada T
Carcinogenesis; 1993 Jul; 14(7):1271-8. PubMed ID: 8330339
[TBL] [Abstract][Full Text] [Related]
8. Use of a newly developed tester strain Salmonella typhimurium NM2009 for the study of metabolic activation of carcinogenic aromatic amines by rat liver microsomal cytochrome P-450 enzymes.
Yamazaki H; Oda Y; Shimada T
Mutat Res; 1992 Oct; 272(2):183-92. PubMed ID: 1383750
[TBL] [Abstract][Full Text] [Related]
9. Activation of procarcinogens by human cytochrome P450 enzymes expressed in Escherichia coli. Simplified bacterial systems for genotoxicity assays.
Shimada T; Gillam EM; Sandhu P; Guo Z; Tukey RH; Guengerich FP
Carcinogenesis; 1994 Nov; 15(11):2523-9. PubMed ID: 7955101
[TBL] [Abstract][Full Text] [Related]
10. Influence of P450 3A4 SRS-2 residues on cooperativity and/or regioselectivity of aflatoxin B(1) oxidation.
Xue L; Wang HF; Wang Q; Szklarz GD; Domanski TL; Halpert JR; Correia MA
Chem Res Toxicol; 2001 May; 14(5):483-91. PubMed ID: 11368545
[TBL] [Abstract][Full Text] [Related]
11. Metabolism of 5-methylchrysene and 6-methylchrysene by human hepatic and pulmonary cytochrome P450 enzymes.
Koehl W; Amin S; Staretz ME; Ueng YF; Yamazaki H; Tateishi T; Guengerich FP; Hecht SS
Cancer Res; 1996 Jan; 56(2):316-24. PubMed ID: 8542586
[TBL] [Abstract][Full Text] [Related]
12. Metabolic activation of carcinogenic 1-nitropyrene by human cytochrome P450 1B1 in Salmonella typhimurium strain expressing an O-acetyltransferase in SOS/umu assay.
Hatanaka N; Yamazaki H; Oda Y; Guengerich FP; Nakajima M; Yokoi T
Mutat Res; 2001 Oct; 497(1-2):223-33. PubMed ID: 11525925
[TBL] [Abstract][Full Text] [Related]
13. Structure-function relationships of human liver cytochromes P450 3A: aflatoxin B1 metabolism as a probe.
Wang H; Dick R; Yin H; Licad-Coles E; Kroetz DL; Szklarz G; Harlow G; Halpert JR; Correia MA
Biochemistry; 1998 Sep; 37(36):12536-45. PubMed ID: 9730826
[TBL] [Abstract][Full Text] [Related]
14. Metabolic activation of heterocyclic amines and other procarcinogens in Salmonella typhimurium umu tester strains expressing human cytochrome P4501A1, 1A2, 1B1, 2C9, 2D6, 2E1, and 3A4 and human NADPH-P450 reductase and bacterial O-acetyltransferase.
Oda Y; Aryal P; Terashita T; Gillam EM; Guengerich FP; Shimada T
Mutat Res; 2001 May; 492(1-2):81-90. PubMed ID: 11377247
[TBL] [Abstract][Full Text] [Related]
15. Escherichia coli MTC, a human NADPH P450 reductase competent mutagenicity tester strain for the expression of human cytochrome P450 isoforms 1A1, 1A2, 2A6, 3A4, or 3A5: catalytic activities and mutagenicity studies.
Kranendonk M; Carreira F; Theisen P; Laires A; Fisher CW; Rueff J; Estabrook RW; Vermeulen NP
Mutat Res; 1999 Apr; 441(1):73-83. PubMed ID: 10224324
[TBL] [Abstract][Full Text] [Related]
16. Activation of 6-aminochrysene to genotoxic products by different forms of rat liver cytochrome P450 in an O-acetyltransferase-overexpressing Salmonella typhimurium strain (NM2009).
Yamazaki H; Shimada T
Biochem Pharmacol; 1992 Sep; 44(5):913-20. PubMed ID: 1530660
[TBL] [Abstract][Full Text] [Related]
17. Human cytochrome P4502B6: interindividual hepatic expression, substrate specificity, and role in procarcinogen activation.
Code EL; Crespi CL; Penman BW; Gonzalez FJ; Chang TK; Waxman DJ
Drug Metab Dispos; 1997 Aug; 25(8):985-93. PubMed ID: 9280407
[TBL] [Abstract][Full Text] [Related]
18. Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of N-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes.
Yamazaki H; Inui Y; Yun CH; Guengerich FP; Shimada T
Carcinogenesis; 1992 Oct; 13(10):1789-94. PubMed ID: 1423839
[TBL] [Abstract][Full Text] [Related]
19. Metabolism of risperidone to 9-hydroxyrisperidone by human cytochromes P450 2D6 and 3A4.
Fang J; Bourin M; Baker GB
Naunyn Schmiedebergs Arch Pharmacol; 1999 Feb; 359(2):147-51. PubMed ID: 10048600
[TBL] [Abstract][Full Text] [Related]
20. Expression of modified human cytochrome P450 3A4 in Escherichia coli and purification and reconstitution of the enzyme.
Gillam EM; Baba T; Kim BR; Ohmori S; Guengerich FP
Arch Biochem Biophys; 1993 Aug; 305(1):123-31. PubMed ID: 8342945
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]