163 related articles for article (PubMed ID: 7558444)
1. Differential inactivation of O6-methylguanine-DNA methyltransferase activity by O6-arylmethylguanines.
Mineura K; Fukuchi M; Kowada M; Terashima I; Kohda K
Int J Cancer; 1995 Sep; 63(1):148-51. PubMed ID: 7558444
[TBL] [Abstract][Full Text] [Related]
2. [Study on potentiation of nitrosourea-cytotoxicity by DNA repair enzyme inhibitors in human brain tumor cells].
Fukuchi M; Mineura K; Kowada M; Terashima I; Kohda K
No To Shinkei; 1997 Jun; 49(6):521-8. PubMed ID: 9198092
[TBL] [Abstract][Full Text] [Related]
3. Enhancement effect of O6-fluorobenzylguanines on chloroethylnitrosourea cytotoxicity in tumor cells.
Mineura K; Fukuchi M; Kowada M; Hitomi K; Terashima I; Kohda K
Life Sci; 1996; 58(19):PL303-8. PubMed ID: 8632694
[TBL] [Abstract][Full Text] [Related]
4. Potentiation of the cytotoxicity of chloroethylnitrosourea by O6-arylmethylguanines.
Kohda K; Terashima I; Koyama K; Watanabe K; Mineura K
Biol Pharm Bull; 1995 Mar; 18(3):424-30. PubMed ID: 7550096
[TBL] [Abstract][Full Text] [Related]
5. Modulation of O6-methylguanine-DNA methyltransferase-mediated 1-(4-amino-2-methyl-5-pyrimidinyl) methyl-3-(2-chloroethyl)-3-nitrosourea resistance by O6-benzylguanine in vitro and in vivo.
Chen JM; Zhang YP; Sui JL; Moschel RC; Ikenaga M
Anticancer Res; 1993; 13(3):801-5. PubMed ID: 8317915
[TBL] [Abstract][Full Text] [Related]
6. Depletion of O6-methylguanine-DNA methyltransferase and potentiation of 1,3-bis(2-chloroethyl)-1-nitrosourea antitumor activity by O6-benzylguanine in vitro.
Chen JM; Zhang YP; Moschel RC; Ikenaga M
Carcinogenesis; 1993 May; 14(5):1057-60. PubMed ID: 8504466
[TBL] [Abstract][Full Text] [Related]
7. Enhancing effect of O6-alkylguanine derivatives on chloroethylnitrosourea cytotoxicity toward tumor cells.
Mineura K; Izumi I; Watanabe K; Kowada M; Kohda K; Koyama K; Terashima I; Ikenaga M
Int J Cancer; 1994 Sep; 58(5):706-12. PubMed ID: 8077057
[TBL] [Abstract][Full Text] [Related]
8. Extended depletion of O6-methylguanine-DNA methyltransferase activity following O6-benzyl-2'-deoxyguanosine or O6-benzylguanine combined with streptozotocin treatment enhances 1,3-bis(2-chloroethyl)-1-nitrosourea cytotoxicity.
Marathi UK; Dolan ME; Erickson LC
Cancer Res; 1994 Aug; 54(16):4371-5. PubMed ID: 8044784
[TBL] [Abstract][Full Text] [Related]
9. O6-(fluorobenzyl)guanine and chloroethylnitrosourea in xenografted rat brain tumor in vivo.
Takahashi M; Mineura K; Watanabe K; Kohda K
Acta Oncol; 2000; 39(1):89-95. PubMed ID: 10752660
[TBL] [Abstract][Full Text] [Related]
10. Potential of O6-methylguanine or O6-benzylguanine in the enhancement of chloroethylnitrosourea cytotoxicity on brain tumours.
Mineura K; Izumi I; Watanabe K; Kowada M; Kohda K; Ikenaga M
Acta Neurochir (Wien); 1994; 128(1-4):13-20. PubMed ID: 7847129
[TBL] [Abstract][Full Text] [Related]
11. O6-methylguanine-DNA methyltransferase (MGMT) transfectants of a 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU)-sensitive colon cancer cell line selectively repopulate heterogenous MGMT+/MGMT- xenografts after BCNU and O6-benzylguanine plus BCNU.
Phillips WP; Willson JK; Markowitz SD; Zborowska E; Zaidi NH; Liu L; Gordon NH; Gerson SL
Cancer Res; 1997 Nov; 57(21):4817-23. PubMed ID: 9354444
[TBL] [Abstract][Full Text] [Related]
12. Retroviral-mediated expression of the P140A, but not P140A/G156A, mutant form of O6-methylguanine DNA methyltransferase protects hematopoietic cells against O6-benzylguanine sensitization to chloroethylnitrosourea treatment.
Maze R; Kurpad C; Pegg AE; Erickson LC; Williams DA
J Pharmacol Exp Ther; 1999 Sep; 290(3):1467-74. PubMed ID: 10454526
[TBL] [Abstract][Full Text] [Related]
13. Transfer and expression of human O6-methylguanine-DNA methyltransferase cDNA confers resistance of Mer- HeLa MR cells to 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosoure a.
Yang J; Chen JM; Zhang YP
Carcinogenesis; 1995 Sep; 16(9):2271-4. PubMed ID: 7554090
[TBL] [Abstract][Full Text] [Related]
14. Increased killing of prostate, breast, colon, and lung tumor cells by the combination of inactivators of O6-alkylguanine-DNA alkyltransferase and N,N'-bis(2-chloroethyl)-N-nitrosourea.
Pegg AE; Swenn K; Chae MY; Dolan ME; Moschel RC
Biochem Pharmacol; 1995 Oct; 50(8):1141-8. PubMed ID: 7488227
[TBL] [Abstract][Full Text] [Related]
15. Effect of DNA on the inactivation of O6-alkylguanine-DNA alkyltransferase by 9-substituted O6-benzylguanine derivatives.
Pegg AE; Chung L; Moschel RC
Biochem Pharmacol; 1997 May; 53(10):1559-64. PubMed ID: 9260884
[TBL] [Abstract][Full Text] [Related]
16. Influence of O6-methylguanine-DNA methyltransferase activity on chloroethylnitrosourea chemotherapy in brain tumors.
Mineura K; Izumi I; Watanabe K; Kowada M
Int J Cancer; 1993 Aug; 55(1):76-81. PubMed ID: 8393842
[TBL] [Abstract][Full Text] [Related]
17. Sensitization of pancreatic tumor xenografts to carmustine and temozolomide by inactivation of their O6-Methylguanine-DNA methyltransferase with O6-benzylguanine or O6-benzyl-2'-deoxyguanosine.
Kokkinakis DM; Ahmed MM; Chendil D; Moschel RC; Pegg AE
Clin Cancer Res; 2003 Sep; 9(10 Pt 1):3801-7. PubMed ID: 14506174
[TBL] [Abstract][Full Text] [Related]
18. Prolonged depletion of O6-methylguanine DNA methyltransferase activity following exposure to O6-benzylguanine with or without streptozotocin enhances 1,3-bis(2-chloroethyl)-1-nitrosourea sensitivity in vitro.
Marathi UK; Kroes RA; Dolan ME; Erickson LC
Cancer Res; 1993 Sep; 53(18):4281-6. PubMed ID: 8364924
[TBL] [Abstract][Full Text] [Related]
19. Depletion of O6-methylguanine-DNA methyltransferase by O6-benzylguanine enhances 5-FU cytotoxicity in colon and oral cancer cell lines.
Murakami J; Lee YJ; Kokeguchi S; Tsujigiwa H; Asaumi J; Nagatsuka H; Fukui K; Kuroda M; Tanaka N; Matsubara N
Oncol Rep; 2007 Jun; 17(6):1461-7. PubMed ID: 17487405
[TBL] [Abstract][Full Text] [Related]
20. O6-methylguanine-DNA methyltransferase, O6-benzylguanine, and resistance to clinical alkylators in pediatric primary brain tumor cell lines.
Bobola MS; Silber JR; Ellenbogen RG; Geyer JR; Blank A; Goff RD
Clin Cancer Res; 2005 Apr; 11(7):2747-55. PubMed ID: 15814657
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]