BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

276 related articles for article (PubMed ID: 7559495)

  • 1. Identification of residues that stabilize the single-chain Fv of monoclonal antibodies B3.
    Benhar I; Pastan I
    J Biol Chem; 1995 Oct; 270(40):23373-80. PubMed ID: 7559495
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rapid humanization of the Fv of monoclonal antibody B3 by using framework exchange of the recombinant immunotoxin B3(Fv)-PE38.
    Benhar I; Padlan EA; Jung SH; Lee B; Pastan I
    Proc Natl Acad Sci U S A; 1994 Dec; 91(25):12051-5. PubMed ID: 7991583
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cloning, expression and characterization of the Fv fragments of the anti-carbohydrate mAbs B1 and B5 as single-chain immunotoxins.
    Benhar I; Pastan I
    Protein Eng; 1994 Dec; 7(12):1509-15. PubMed ID: 7716163
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Recombinant immunotoxins containing the VH or VL domain of monoclonal antibody B3 fused to Pseudomonas exotoxin.
    Brinkmann U; Lee BK; Pastan I
    J Immunol; 1993 Apr; 150(7):2774-82. PubMed ID: 8454854
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of B1(Fv)PE38 and B1(dsFv)PE38: single-chain and disulfide-stabilized Fv immunotoxins with increased activity that cause complete remissions of established human carcinoma xenografts in nude mice.
    Benhar I; Pastan I
    Clin Cancer Res; 1995 Sep; 1(9):1023-9. PubMed ID: 9816075
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lowering the isoelectric point of the Fv portion of recombinant immunotoxins leads to decreased nonspecific animal toxicity without affecting antitumor activity.
    Onda M; Nagata S; Tsutsumi Y; Vincent JJ; Wang Q; Kreitman RJ; Lee B; Pastan I
    Cancer Res; 2001 Jul; 61(13):5070-7. PubMed ID: 11431343
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Administration of disulfide-stabilized Fv-immunotoxins B1(dsFv)-PE38 and B3(dsFv)-PE38 by continuous infusion increases their efficacy in curing large tumor xenografts in nude mice.
    Benhar I; Reiter Y; Pai LH; Pastan I
    Int J Cancer; 1995 Jul; 62(3):351-5. PubMed ID: 7628878
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Engineering interchain disulfide bonds into conserved framework regions of Fv fragments: improved biochemical characteristics of recombinant immunotoxins containing disulfide-stabilized Fv.
    Reiter Y; Brinkmann U; Webber KO; Jung SH; Lee B; Pastan I
    Protein Eng; 1994 May; 7(5):697-704. PubMed ID: 8073039
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design of interchain disulfide bonds in the framework region of the Fv fragment of the monoclonal antibody B3.
    Jung SH; Pastan I; Lee B
    Proteins; 1994 May; 19(1):35-47. PubMed ID: 8066084
    [TBL] [Abstract][Full Text] [Related]  

  • 10. B3(Fv)-PE38KDEL, a single-chain immunotoxin that causes complete regression of a human carcinoma in mice.
    Brinkmann U; Pai LH; FitzGerald DJ; Willingham M; Pastan I
    Proc Natl Acad Sci U S A; 1991 Oct; 88(19):8616-20. PubMed ID: 1924323
    [TBL] [Abstract][Full Text] [Related]  

  • 11. B3(Fab)-PE38M: a recombinant immunotoxin in which a mutant form of Pseudomonas exotoxin is fused to the Fab fragment of monoclonal antibody B3.
    Choe M; Webber KO; Pastan I
    Cancer Res; 1994 Jul; 54(13):3460-7. PubMed ID: 8012967
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Immunotoxins containing Pseudomonas exotoxin that target LeY damage human endothelial cells in an antibody-specific mode: relevance to vascular leak syndrome.
    Kuan CT; Pai LH; Pastan I
    Clin Cancer Res; 1995 Dec; 1(12):1589-94. PubMed ID: 9815960
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A recombinant immunotoxin containing a disulfide-stabilized Fv fragment.
    Brinkmann U; Reiter Y; Jung SH; Lee B; Pastan I
    Proc Natl Acad Sci U S A; 1993 Aug; 90(16):7538-42. PubMed ID: 8356052
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A protease-resistant immunotoxin against CD22 with greatly increased activity against CLL and diminished animal toxicity.
    Weldon JE; Xiang L; Chertov O; Margulies I; Kreitman RJ; FitzGerald DJ; Pastan I
    Blood; 2009 Apr; 113(16):3792-800. PubMed ID: 18988862
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cytotoxicity of antiosteosarcoma recombinant immunotoxins composed of TP-3 Fv fragments and a truncated Pseudomonas exotoxin A.
    Onda M; Olafsen T; Tsutsumi Y; Bruland OS; Pastan I
    J Immunother; 2001; 24(2):144-50. PubMed ID: 11265772
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Role of caspases in immunotoxin-induced apoptosis of cancer cells.
    Keppler-Hafkemeyer A; Brinkmann U; Pastan I
    Biochemistry; 1998 Dec; 37(48):16934-42. PubMed ID: 9836586
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Single-chain immunotoxin fusions between anti-Tac and Pseudomonas exotoxin: relative importance of the two toxin disulfide bonds.
    Kreitman RJ; Batra JK; Seetharam S; Chaudhary VK; FitzGerald DJ; Pastan I
    Bioconjug Chem; 1993; 4(2):112-20. PubMed ID: 7873642
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A recombinant immunotoxin that is active on prostate cancer cells and that is composed of the Fv region of monoclonal antibody PR1 and a truncated form of Pseudomonas exotoxin.
    Brinkmann U; Gallo M; Brinkmann E; Kunwar S; Pastan I
    Proc Natl Acad Sci U S A; 1993 Jan; 90(2):547-51. PubMed ID: 8421689
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Recombinant single-chain and disulfide-stabilized Fv-immunotoxins that cause complete regression of a human colon cancer xenograft in nude mice.
    Reiter Y; Wright AF; Tonge DW; Pastan I
    Int J Cancer; 1996 Jul; 67(1):113-23. PubMed ID: 8690511
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Cytotoxic and antitumor activity of a recombinant immunotoxin composed of disulfide-stabilized anti-Tac Fv fragment and truncated Pseudomonas exotoxin.
    Reiter Y; Kreitman RJ; Brinkmann U; Pastan I
    Int J Cancer; 1994 Jul; 58(1):142-9. PubMed ID: 8014011
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.