247 related articles for article (PubMed ID: 7559526)
1. Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase resistant to multiple 2',3'-dideoxynucleoside 5'-triphosphates.
Ueno T; Shirasaka T; Mitsuya H
J Biol Chem; 1995 Oct; 270(40):23605-11. PubMed ID: 7559526
[TBL] [Abstract][Full Text] [Related]
2. Comparative enzymatic study of HIV-1 reverse transcriptase resistant to 2',3'-dideoxynucleotide analogs using the single-nucleotide incorporation assay.
Ueno T; Mitsuya H
Biochemistry; 1997 Feb; 36(5):1092-9. PubMed ID: 9033399
[TBL] [Abstract][Full Text] [Related]
3. The molecular mechanism of multidrug resistance by the Q151M human immunodeficiency virus type 1 reverse transcriptase and its suppression using alpha-boranophosphate nucleotide analogues.
Deval J; Selmi B; Boretto J; Egloff MP; Guerreiro C; Sarfati S; Canard B
J Biol Chem; 2002 Nov; 277(44):42097-104. PubMed ID: 12194983
[TBL] [Abstract][Full Text] [Related]
4. The K65R mutant reverse transcriptase of HIV-1 cross-resistant to 2', 3'-dideoxycytidine, 2',3'-dideoxy-3'-thiacytidine, and 2',3'-dideoxyinosine shows reduced sensitivity to specific dideoxynucleoside triphosphate inhibitors in vitro.
Gu Z; Fletcher RS; Arts EJ; Wainberg MA; Parniak MA
J Biol Chem; 1994 Nov; 269(45):28118-22. PubMed ID: 7525567
[TBL] [Abstract][Full Text] [Related]
5. Enzymatic properties of two mutants of reverse transcriptase of human immunodeficiency virus type 1 (tyrosine 181-->isoleucine and tyrosine 188-->leucine), resistant to nonnucleoside inhibitors.
Loya S; Bakhanashvili M; Tal R; Hughes SH; Boyer PL; Hizi A
AIDS Res Hum Retroviruses; 1994 Aug; 10(8):939-46. PubMed ID: 7529032
[TBL] [Abstract][Full Text] [Related]
6. Interactions of the HIV-1 reverse transcriptase 'AZT-resistant' mutant with substrates and AZT-TP.
Pokholok DK; Gudima SO; Yesipov DS; Dobrynin VN; Rechinsky VO; Kochetkov SN
FEBS Lett; 1993 Jul; 325(3):237-41. PubMed ID: 7686510
[TBL] [Abstract][Full Text] [Related]
7. A rapid phenotypic assay for detecting multiple nucleoside analogue reverse transcriptase inhibitor-resistant HIV-1 in plasma.
Qari SH; Winters M; Vandamme AM; Merigan T; Heneine W
Antivir Ther; 2002 Jun; 7(2):131-9. PubMed ID: 12212925
[TBL] [Abstract][Full Text] [Related]
8. Human immunodeficiency virus type 1 reverse transcriptase. 3'-Azidodeoxythymidine 5'-triphosphate inhibition indicates two-step binding for template-primer.
Jaju M; Beard WA; Wilson SH
J Biol Chem; 1995 Apr; 270(17):9740-7. PubMed ID: 7537269
[TBL] [Abstract][Full Text] [Related]
9. Effects of HIV Q151M-associated multi-drug resistance mutations on the activities of (-)-beta-D-1',3'-dioxolan guanine.
Feng JY; Myrick F; Selmi B; Deval J; Canard B; Borroto-Esoda K
Antiviral Res; 2005 Jun; 66(2-3):153-8. PubMed ID: 15885814
[TBL] [Abstract][Full Text] [Related]
10. Human immunodeficiency virus reverse transcriptase. Substrate and inhibitor kinetics with thymidine 5'-triphosphate and 3'-azido-3'-deoxythymidine 5'-triphosphate.
Reardon JE; Miller WH
J Biol Chem; 1990 Nov; 265(33):20302-7. PubMed ID: 1700787
[TBL] [Abstract][Full Text] [Related]
11. 3'-Azido-3',5'-dideoxythymidine-5'-methylphosphonic acid diphosphate: synthesis and HIV-1 reverse transcriptase inhibition.
Freeman GA; Rideout JL; Miller WH; Reardon JE
J Med Chem; 1992 Aug; 35(17):3192-6. PubMed ID: 1380561
[TBL] [Abstract][Full Text] [Related]
12. Biochemical characterization of a multi-drug resistant HIV-1 subtype AG reverse transcriptase: antagonism of AZT discrimination and excision pathways and sensitivity to RNase H inhibitors.
Schneider A; Corona A; Spöring I; Jordan M; Buchholz B; Maccioni E; Di Santo R; Bodem J; Tramontano E; Wöhrl BM
Nucleic Acids Res; 2016 Mar; 44(5):2310-22. PubMed ID: 26850643
[TBL] [Abstract][Full Text] [Related]
13. Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides.
Shirasaka T; Kavlick MF; Ueno T; Gao WY; Kojima E; Alcaide ML; Chokekijchai S; Roy BM; Arnold E; Yarchoan R
Proc Natl Acad Sci U S A; 1995 Mar; 92(6):2398-402. PubMed ID: 7534421
[TBL] [Abstract][Full Text] [Related]
14. Molecular mechanism by which the K70E mutation in human immunodeficiency virus type 1 reverse transcriptase confers resistance to nucleoside reverse transcriptase inhibitors.
Sluis-Cremer N; Sheen CW; Zelina S; Torres PS; Parikh UM; Mellors JW
Antimicrob Agents Chemother; 2007 Jan; 51(1):48-53. PubMed ID: 17088490
[TBL] [Abstract][Full Text] [Related]
15. Lack of synergy in the inhibition of HIV-1 reverse transcriptase by combinations of the 5'-triphosphates of various anti-HIV nucleoside analogs.
White EL; Parker WB; Ross LJ; Shannon WM
Antiviral Res; 1993 Dec; 22(4):295-308. PubMed ID: 7506513
[TBL] [Abstract][Full Text] [Related]
16. Mechanism of inhibition of human immunodeficiency virus type 1 reverse transcriptase and human DNA polymerases alpha, beta, and gamma by the 5'-triphosphates of carbovir, 3'-azido-3'-deoxythymidine, 2',3'-dideoxyguanosine and 3'-deoxythymidine. A novel RNA template for the evaluation of antiretroviral drugs.
Parker WB; White EL; Shaddix SC; Ross LJ; Buckheit RW; Germany JM; Secrist JA; Vince R; Shannon WM
J Biol Chem; 1991 Jan; 266(3):1754-62. PubMed ID: 1703154
[TBL] [Abstract][Full Text] [Related]
17. Multidrug-resistant human immunodeficiency virus type 1 strains resulting from combination antiretroviral therapy.
Iversen AK; Shafer RW; Wehrly K; Winters MA; Mullins JI; Chesebro B; Merigan TC
J Virol; 1996 Feb; 70(2):1086-90. PubMed ID: 8551567
[TBL] [Abstract][Full Text] [Related]
18. Structural Insights into HIV Reverse Transcriptase Mutations Q151M and Q151M Complex That Confer Multinucleoside Drug Resistance.
Das K; Martinez SE; Arnold E
Antimicrob Agents Chemother; 2017 Jun; 61(6):. PubMed ID: 28396546
[TBL] [Abstract][Full Text] [Related]
19. Pharmacodynamic studies (PD) of didanosine (ddI) alone and in combination with azidothymidine (AZT) in human T-cells; a stochastic biochemical approach to antiretroviral nucleoside drug combination in inhibiting HIV-reverse transcriptase (RT).
Periclou AP; Nandy P; Avramis VI
In Vivo; 2000; 14(3):377-88. PubMed ID: 10904870
[TBL] [Abstract][Full Text] [Related]
20. Pre-steady-state kinetic characterization of wild type and 3'-azido-3'-deoxythymidine (AZT) resistant human immunodeficiency virus type 1 reverse transcriptase: implication of RNA directed DNA polymerization in the mechanism of AZT resistance.
Kerr SG; Anderson KS
Biochemistry; 1997 Nov; 36(46):14064-70. PubMed ID: 9369478
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]