199 related articles for article (PubMed ID: 7559592)
1. Identification of a Gs coupling domain in the amino terminus of the third intracellular loop of the alpha 2A-adrenergic receptor. Evidence for distinct structural determinants that confer Gs versus Gi coupling.
Eason MG; Liggett SB
J Biol Chem; 1995 Oct; 270(42):24753-60. PubMed ID: 7559592
[TBL] [Abstract][Full Text] [Related]
2. Simultaneous coupling of alpha 2-adrenergic receptors to two G-proteins with opposing effects. Subtype-selective coupling of alpha 2C10, alpha 2C4, and alpha 2C2 adrenergic receptors to Gi and Gs.
Eason MG; Kurose H; Holt BD; Raymond JR; Liggett SB
J Biol Chem; 1992 Aug; 267(22):15795-801. PubMed ID: 1322406
[TBL] [Abstract][Full Text] [Related]
3. The palmitoylated cysteine of the cytoplasmic tail of alpha 2A-adrenergic receptors confers subtype-specific agonist-promoted downregulation.
Eason MG; Jacinto MT; Theiss CT; Liggett SB
Proc Natl Acad Sci U S A; 1994 Nov; 91(23):11178-82. PubMed ID: 7972030
[TBL] [Abstract][Full Text] [Related]
4. Chimeric mutagenesis of putative G-protein coupling domains of the alpha2A-adrenergic receptor. Localization of two redundant and fully competent gi coupling domains.
Eason MG; Liggett SB
J Biol Chem; 1996 May; 271(22):12826-32. PubMed ID: 8662784
[TBL] [Abstract][Full Text] [Related]
5. Contribution of ligand structure to activation of alpha 2-adrenergic receptor subtype coupling to Gs.
Eason MG; Jacinto MT; Liggett SB
Mol Pharmacol; 1994 Apr; 45(4):696-702. PubMed ID: 7910371
[TBL] [Abstract][Full Text] [Related]
6. Coupling of a mutated form of the human beta 2-adrenergic receptor to Gi and Gs. Requirement for multiple cytoplasmic domains in the coupling process.
Liggett SB; Caron MG; Lefkowitz RJ; Hnatowich M
J Biol Chem; 1991 Mar; 266(8):4816-21. PubMed ID: 1848226
[TBL] [Abstract][Full Text] [Related]
7. Four consecutive serines in the third intracellular loop are the sites for beta-adrenergic receptor kinase-mediated phosphorylation and desensitization of the alpha 2A-adrenergic receptor.
Eason MG; Moreira SP; Liggett SB
J Biol Chem; 1995 Mar; 270(9):4681-8. PubMed ID: 7876239
[TBL] [Abstract][Full Text] [Related]
8. Role of the amino terminus of the third intracellular loop in agonist-promoted downregulation of the alpha2A-adrenergic receptor.
Jewell-Motz EA; Donnelly ET; Eason MG; Liggett SB
Biochemistry; 1997 Jul; 36(29):8858-63. PubMed ID: 9220972
[TBL] [Abstract][Full Text] [Related]
9. Functional alpha 2-adrenergic receptor-Gs coupling undergoes agonist-promoted desensitization in a subtype-selective manner.
Eason MG; Liggett SB
Biochem Biophys Res Commun; 1993 May; 193(1):318-23. PubMed ID: 8099284
[TBL] [Abstract][Full Text] [Related]
10. Sites in the third intracellular loop of the alpha 2A-adrenergic receptor confer short term agonist-promoted desensitization. Evidence for a receptor kinase-mediated mechanism.
Liggett SB; Ostrowski J; Chesnut LC; Kurose H; Raymond JR; Caron MG; Lefkowitz RJ
J Biol Chem; 1992 Mar; 267(7):4740-6. PubMed ID: 1311318
[TBL] [Abstract][Full Text] [Related]
11. Subtype-selective desensitization of alpha 2-adrenergic receptors. Different mechanisms control short and long term agonist-promoted desensitization of alpha 2C10, alpha 2C4, and alpha 2C2.
Eason MG; Liggett SB
J Biol Chem; 1992 Dec; 267(35):25473-9. PubMed ID: 1334095
[TBL] [Abstract][Full Text] [Related]
12. G(i) activator region of alpha(2A)-adrenergic receptors: distinct basic residues mediate G(i) versus G(s) activation.
Wade SM; Lim WK; Lan KL; Chung DA; Nanamori M; Neubig RR
Mol Pharmacol; 1999 Nov; 56(5):1005-13. PubMed ID: 10531407
[TBL] [Abstract][Full Text] [Related]
13. Gi alpha 1 selectively couples somatostatin receptor subtype 3 to adenylyl cyclase: identification of the functional domains of this alpha subunit necessary for mediating the inhibition by somatostatin of cAMP formation.
Law SF; Zaina S; Sweet R; Yasuda K; Bell GI; Stadel J; Reisine T
Mol Pharmacol; 1994 Apr; 45(4):587-90. PubMed ID: 8183236
[TBL] [Abstract][Full Text] [Related]
14. Coupling of the alpha 2A-adrenergic receptor to multiple G-proteins. A simple approach for estimating receptor-G-protein coupling efficiency in a transient expression system.
Chabre O; Conklin BR; Brandon S; Bourne HR; Limbird LE
J Biol Chem; 1994 Feb; 269(8):5730-4. PubMed ID: 7907086
[TBL] [Abstract][Full Text] [Related]
15. Hamster alpha 1B-adrenergic receptor directly activates Gs in the transfected Chinese hamster ovary cells.
Horie K; Itoh H; Tsujimoto G
Mol Pharmacol; 1995 Sep; 48(3):392-400. PubMed ID: 7565618
[TBL] [Abstract][Full Text] [Related]
16. Mutations of the human beta 2-adrenergic receptor that impair coupling to Gs interfere with receptor down-regulation but not sequestration.
Campbell PT; Hnatowich M; O'Dowd BF; Caron MG; Lefkowitz RJ; Hausdorff WP
Mol Pharmacol; 1991 Feb; 39(2):192-8. PubMed ID: 1847493
[TBL] [Abstract][Full Text] [Related]
17. Serine 232 of the alpha(2A)-adrenergic receptor is a protein kinase C-sensitive effector coupling switch.
Liang M; Freedman NJ; Theiss CT; Liggett SB
Biochemistry; 2001 Dec; 40(49):15031-7. PubMed ID: 11732925
[TBL] [Abstract][Full Text] [Related]
18. A proline-rich region of the third intracellular loop imparts phenotypic beta 1-versus beta 2-adrenergic receptor coupling and sequestration.
Green SA; Liggett SB
J Biol Chem; 1994 Oct; 269(42):26215-9. PubMed ID: 7929336
[TBL] [Abstract][Full Text] [Related]
19. An asn to lys polymorphism in the third intracellular loop of the human alpha 2A-adrenergic receptor imparts enhanced agonist-promoted Gi coupling.
Small KM; Forbes SL; Brown KM; Liggett SB
J Biol Chem; 2000 Dec; 275(49):38518-23. PubMed ID: 10948191
[TBL] [Abstract][Full Text] [Related]
20. Alpha 2A-adrenergic receptor stimulated calcium release is transduced by Gi-associated G(beta gamma)-mediated activation of phospholipase C.
Dorn GW; Oswald KJ; McCluskey TS; Kuhel DG; Liggett SB
Biochemistry; 1997 May; 36(21):6415-23. PubMed ID: 9174358
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
