BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

228 related articles for article (PubMed ID: 7559796)

  • 1. Increased tumorigenicity in the human pancreatic cell line MIA PaCa-2 is associated with an aberrant regulation of an IGF-1 autocrine loop and lack of expression of the TGF-beta type RII receptor.
    Freeman JW; Mattingly CA; Strodel WE
    J Cell Physiol; 1995 Oct; 165(1):155-63. PubMed ID: 7559796
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Aberrant expression and activation of insulin-like growth factor-1 receptor (IGF-1R) are mediated by an induction of IGF-1R promoter activity and stabilization of IGF-1R mRNA and contributes to growth factor independence and increased survival of the pancreatic cancer cell line MIA PaCa-2.
    Nair PN; De Armond DT; Adamo ML; Strodel WE; Freeman JW
    Oncogene; 2001 Dec; 20(57):8203-14. PubMed ID: 11781836
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Nerve growth factor exerts differential effects on the growth of human pancreatic cancer cells.
    Zhu ZW; Friess H; Wang L; Bogardus T; Korc M; Kleeff J; Büchler MW
    Clin Cancer Res; 2001 Jan; 7(1):105-12. PubMed ID: 11205897
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Farnesyltransferase inhibitor (L-744,832) restores TGF-beta type II receptor expression and enhances radiation sensitivity in K-ras mutant pancreatic cancer cell line MIA PaCa-2.
    Alcock RA; Dey S; Chendil D; Inayat MS; Mohiuddin M; Hartman G; Chatfield LK; Gallicchio VS; Ahmed MM
    Oncogene; 2002 Nov; 21(51):7883-90. PubMed ID: 12420225
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insulin-like growth factor I and transforming growth factor alpha as autocrine growth factors in human pancreatic cancer cell growth.
    Ohmura E; Okada M; Onoda N; Kamiya Y; Murakami H; Tsushima T; Shizume K
    Cancer Res; 1990 Jan; 50(1):103-7. PubMed ID: 2152769
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Reversion of transcriptional repression of Sp1 by 5 aza-2' deoxycytidine restores TGF-beta type II receptor expression in the pancreatic cancer cell line MIA PaCa-2.
    Venkatasubbarao K; Ammanamanchi S; Brattain MG; Mimari D; Freeman JW
    Cancer Res; 2001 Aug; 61(16):6239-47. PubMed ID: 11507078
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Contextual effects of transforming growth factor beta on the tumorigenicity of human colon carcinoma cells.
    Ye SC; Foster JM; Li W; Liang J; Zborowska E; Venkateswarlu S; Gong J; Brattain MG; Willson JK
    Cancer Res; 1999 Sep; 59(18):4725-31. PubMed ID: 10493532
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Insulin-like growth factor-II expression in carcinoma in colon cell lines: implications for autocrine actions.
    Guo YS; Jin GF; Townsend CM; Zhang T; Sheng HM; Beauchamp RD; Thompson JC
    J Am Coll Surg; 1995 Aug; 181(2):145-54. PubMed ID: 7627387
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential expression of transforming growth factor beta receptors in human pancreatic adenocarcinoma.
    Venkatasubbarao K; Ahmed MM; Mohiuddin M; Swiderski C; Lee E; Gower WR; Salhab KF; McGrath P; Strodel W; Freeman JW
    Anticancer Res; 2000; 20(1A):43-51. PubMed ID: 10769633
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pancreatic carcinoma cells express neuropilins and vascular endothelial growth factor, but not vascular endothelial growth factor receptors.
    Li M; Yang H; Chai H; Fisher WE; Wang X; Brunicardi FC; Yao Q; Chen C
    Cancer; 2004 Nov; 101(10):2341-50. PubMed ID: 15476280
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Overexpression of epidermal growth factor and insulin-like growth factor-I receptors and autocrine stimulation in human esophageal carcinoma cells.
    Chen SC; Chou CK; Wong FH; Chang CM; Hu CP
    Cancer Res; 1991 Apr; 51(7):1898-903. PubMed ID: 2004373
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Targeting endogenous transforming growth factor beta receptor signaling in SMAD4-deficient human pancreatic carcinoma cells inhibits their invasive phenotype1.
    Subramanian G; Schwarz RE; Higgins L; McEnroe G; Chakravarty S; Dugar S; Reiss M
    Cancer Res; 2004 Aug; 64(15):5200-11. PubMed ID: 15289325
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Soluble type II transforming growth factor-beta (TGF-beta) receptor inhibits TGF-beta signaling in COLO-357 pancreatic cancer cells in vitro and attenuates tumor formation.
    Rowland-Goldsmith MA; Maruyama H; Kusama T; Ralli S; Korc M
    Clin Cancer Res; 2001 Sep; 7(9):2931-40. PubMed ID: 11555612
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of the TGFalpha autocrine loop is downstream of IGF-I receptor activation during mitogenesis in growth factor dependent human colon carcinoma cells.
    Wang D; Patil S; Li W; Humphrey LE; Brattain MG; Howell GM
    Oncogene; 2002 Apr; 21(18):2785-96. PubMed ID: 11973637
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Growth inhibition due to complementation of transforming growth factor-beta receptor type II-defect by human chromosome 3 transfer in human colorectal carcinoma cells.
    Miyafuji Y; Zhong X; Uchida I; Koi M; Hemmi H
    J Cell Physiol; 2001 Jun; 187(3):356-64. PubMed ID: 11319759
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transforming growth factor-alpha and insulin-like growth factor-I, but not epidermal growth factor, elicit autocrine stimulation of mitogenesis in endometrial cancer cell lines.
    Reynolds RK; Hu C; Baker VV
    Gynecol Oncol; 1998 Aug; 70(2):202-9. PubMed ID: 9740691
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insulin-like growth factor (IGF) I down-regulates type 1 IGF receptor (IGF 1R) and reduces the IGF I response in A549 non-small-cell lung cancer and Saos-2/B-10 osteoblastic osteosarcoma cells.
    Bostedt KT; Schmid C; Ghirlanda-Keller C; Olie R; Winterhalter KH; Zapf J
    Exp Cell Res; 2001 Dec; 271(2):368-77. PubMed ID: 11716549
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Induction of p21waf1 expression and growth inhibition by transforming growth factor beta involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells.
    Grau AM; Zhang L; Wang W; Ruan S; Evans DB; Abbruzzese JL; Zhang W; Chiao PJ
    Cancer Res; 1997 Sep; 57(18):3929-34. PubMed ID: 9307274
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rap1 reverses transcriptional repression of TGF-beta type II receptor by a mechanism involving AP-1 in the human pancreatic cancer cell line, UK Pan-1.
    Fralix KD; Zhao S; Venkatasubbarao K; Freeman JW
    J Cell Physiol; 2003 Jan; 194(1):88-99. PubMed ID: 12447993
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Insulin-like growth factor and epidermal growth factor independence in human mammary carcinoma cells with c-erbB-2 gene amplification and progressively elevated levels of tyrosine-phosphorylated p185erbB-2.
    Ram TG; Dilts CA; Dziubinski ML; Pierce LJ; Ethier SP
    Mol Carcinog; 1996 Mar; 15(3):227-38. PubMed ID: 8597535
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.