These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

608 related articles for article (PubMed ID: 7565631)

  • 1. Nicotinamide adenine dinucleotide (phosphate): quinone oxidoreductase (DT-diaphorase) as a target for bioreductive antitumor quinones: quinone cytotoxicity and selectivity in human lung and breast cancer cell lines.
    Beall HD; Murphy AM; Siegel D; Hargreaves RH; Butler J; Ross D
    Mol Pharmacol; 1995 Sep; 48(3):499-504. PubMed ID: 7565631
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases.
    Beall HD; Mulcahy RT; Siegel D; Traver RD; Gibson NW; Ross D
    Cancer Res; 1994 Jun; 54(12):3196-201. PubMed ID: 8205540
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The effect of functional groups on reduction and activation of quinone bioreductive agents by DT-diaphorase.
    Fourie J; Oleschuk CJ; Guziec F; Guziec L; Fiterman DJ; Monterrosa C; Begleiter A
    Cancer Chemother Pharmacol; 2002 Feb; 49(2):101-10. PubMed ID: 11862423
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Bioactivation of quinones by DT-diaphorase, molecular, biochemical, and chemical studies.
    Ross D; Beall H; Traver RD; Siegel D; Phillips RM; Gibson NW
    Oncol Res; 1994; 6(10-11):493-500. PubMed ID: 7620217
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A new screening system for NAD(P)H:quinone oxidoreductase (NQO1)-directed antitumor quinones: identification of a new aziridinylbenzoquinone, RH1, as a NQO1-directed antitumor agent.
    Winski SL; Hargreaves RH; Butler J; Ross D
    Clin Cancer Res; 1998 Dec; 4(12):3083-8. PubMed ID: 9865924
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Elevated DT-diaphorase activity and messenger RNA content in human non-small cell lung carcinoma: relationship to the response of lung tumor xenografts to mitomycin Cł.
    Malkinson AM; Siegel D; Forrest GL; Gazdar AF; Oie HK; Chan DC; Bunn PA; Mabry M; Dykes DJ; Harrison SD
    Cancer Res; 1992 Sep; 52(17):4752-7. PubMed ID: 1324793
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Relationship between DT-diaphorase-mediated metabolism of a series of aziridinylbenzoquinones and DNA damage and cytotoxicity.
    Gibson NW; Hartley JA; Butler J; Siegel D; Ross D
    Mol Pharmacol; 1992 Sep; 42(3):531-6. PubMed ID: 1406604
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Indolequinone antitumor agents: correlation between quinone structure, rate of metabolism by recombinant human NAD(P)H:quinone oxidoreductase, and in vitro cytotoxicity.
    Beall HD; Winski S; Swann E; Hudnott AR; Cotterill AS; O'Sullivan N; Green SJ; Bien R; Siegel D; Ross D; Moody CJ
    J Med Chem; 1998 Nov; 41(24):4755-66. PubMed ID: 9822546
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-activity study with bioreductive benzoquinone alkylating agents: effects on DT-diaphorase-mediated DNA crosslink and strand break formation in relation to mechanisms of cytotoxicity.
    Fourie J; Guziec F; Guziec L; Monterrosa C; Fiterman DJ; Begleiter A
    Cancer Chemother Pharmacol; 2004 Mar; 53(3):191-203. PubMed ID: 14614574
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Induction of DT-diaphorase in cancer chemoprevention and chemotherapy.
    Begleiter A; Leith MK; Curphey TJ; Doherty GP
    Oncol Res; 1997; 9(6-7):371-82. PubMed ID: 9406243
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Bioreductive activation of a series of analogues of 5-aziridinyl-3-hydroxymethyl-1-methyl-2-[1H-indole-4, 7-dione] prop-beta-en-alpha-ol (EO9) by human DT-diaphorase.
    Phillips RM
    Biochem Pharmacol; 1996 Dec; 52(11):1711-8. PubMed ID: 8986133
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Enzyme-directed bioreductive drug development revisited: a commentary on recent progress and future prospects with emphasis on quinone anticancer agents and quinone metabolizing enzymes, particularly DT-diaphorase.
    Workman P
    Oncol Res; 1994; 6(10-11):461-75. PubMed ID: 7620214
    [TBL] [Abstract][Full Text] [Related]  

  • 13. NAD(P)H:quinone oxidoreductase gene expression in human colon carcinoma cells: characterization of a mutation which modulates DT-diaphorase activity and mitomycin sensitivity.
    Traver RD; Horikoshi T; Danenberg KD; Stadlbauer TH; Danenberg PV; Ross D; Gibson NW
    Cancer Res; 1992 Feb; 52(4):797-802. PubMed ID: 1737339
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Expression of human NAD(P)H: quinone oxidoreductase (DT-diaphorase) in Chinese hamster ovary cells: effect on the toxicity of antitumor quinones.
    Gustafson DL; Beall HD; Bolton EM; Ross D; Waldren CA
    Mol Pharmacol; 1996 Oct; 50(4):728-35. PubMed ID: 8863816
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel quinolinequinone antitumor agents: structure-metabolism studies with NAD(P)H:quinone oxidoreductase (NQO1).
    Fryatt T; Pettersson HI; Gardipee WT; Bray KC; Green SJ; Slawin AM; Beall HD; Moody CJ
    Bioorg Med Chem; 2004 Apr; 12(7):1667-87. PubMed ID: 15028260
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DT-diaphorase as a target enzyme for biochemical modulation of mitomycin C.
    Saeki S; Nishiyama M; Toge T
    Hiroshima J Med Sci; 1995 Sep; 44(3):55-63. PubMed ID: 8567314
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mapping of DNA alkylation sites induced by aziridinylbenzoquinones in human cells by ligation-mediated polymerase chain reaction.
    Lee CS; Pfeifer GP; Gibson NW
    Cancer Res; 1994 Apr; 54(7):1622-6. PubMed ID: 8137269
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [DT-diaphorase].
    Mikami K; Shirakusa T; Tsuruo T
    Gan To Kagaku Ryoho; 1997 Sep; 24(11):1606-10. PubMed ID: 9309161
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Catalytic properties of NAD(P)H:quinone acceptor oxidoreductase: study involving mouse, rat, human, and mouse-rat chimeric enzymes.
    Chen S; Knox R; Lewis AD; Friedlos F; Workman P; Deng PS; Fung M; Ebenstein D; Wu K; Tsai TM
    Mol Pharmacol; 1995 May; 47(5):934-9. PubMed ID: 7746280
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DT-diaphorase: a target for new anticancer drugs.
    Danson S; Ward TH; Butler J; Ranson M
    Cancer Treat Rev; 2004 Aug; 30(5):437-49. PubMed ID: 15245776
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 31.