BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

124 related articles for article (PubMed ID: 757314)

  • 1. Studies of the biochemical pharmacology of the fermentation-derived antitumor agent, (alpha S, 5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125).
    Neil GL; Berger AE; Bhuyan BK; Blowers CL; Kuentzel SL
    Adv Enzyme Regul; 1978; 17():375-98. PubMed ID: 757314
    [No Abstract]   [Full Text] [Related]  

  • 2. Biochemical and pharmacological effects of the fermentation-derived antitumor agent, (alphaS,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125).
    Neil GL; Berger AE; McPartland RP; Grindey GB; Bloch A
    Cancer Res; 1979 Mar; 39(3):852-6. PubMed ID: 427775
    [No Abstract]   [Full Text] [Related]  

  • 3. L-[alphaS, 5S]-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (NSC-163501): a new amino acid antibiotic with the properties of an antagonist of L-glutamine.
    Jayaram HN; Cooney DA; Ryan JA; Neil G; Dion RL; Bono VH
    Cancer Chemother Rep; 1975; 59(3):481-91. PubMed ID: 1147
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mechanism of resistance of a variant of P388 leukemia to L-(alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (acivicin).
    Jayaram HN; Ardalan B; Deas M; Johnson RK
    Cancer Res; 1985 Jan; 45(1):207-12. PubMed ID: 2578092
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The inhibition of gamma-glutamyl transpeptidase from human pancreatic carcinoma cells by (alpha S,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125; NSC-163501).
    Allen L; Meck R; Yunis A
    Res Commun Chem Pathol Pharmacol; 1980 Jan; 27(1):175-82. PubMed ID: 6102405
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A new antitumor agent, (alphas, 4s, 5r)-alpha-amino-3-chloro-4-hydroxy-4,5-dihydro-5-isoxazoleacetic acid (NSC-176324): preliminary evaluation against L 1210 mouse leukemia in vivo.
    Martin DG; Hanka LJ; Neil GL
    Cancer Chemother Rep; 1974; 58(6):935-7. PubMed ID: 4217217
    [No Abstract]   [Full Text] [Related]  

  • 7. Acivicin. An antitumor antibiotic.
    Poster DS; Bruno S; Penta J; Neil GL; McGovren JP
    Cancer Clin Trials; 1981; 4(3):327-30. PubMed ID: 7026076
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Enhanced effect of an L-glutamine antagonist, L-(alphaS,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid, by Acinetobacter L-glutaminase-L-asparaginase.
    Holcenberg JS
    Cancer Treat Rep; 1979 Jun; 63(6):1109-14. PubMed ID: 466650
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Collateral sensitivity to N-(phosphonacetyl)-L-aspartic acid in a line of P388 leukemia cells selected for resistance to L-(alpha S, 5S)-alpha-amino-3- chloro-4,5-dihydro-5-isoxazoleacetic acid (acivicin).
    Ardalan B; Jayaram HN; Johnson RK
    Cancer Res; 1983 Apr; 43(4):1598-601. PubMed ID: 6831405
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanism of inactivation of glutamine amidotransferases by the antitumor drug L-(alpha S, 5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125).
    Tso JY; Bower SG; Zalkin H
    J Biol Chem; 1980 Jul; 255(14):6734-8. PubMed ID: 6993476
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Biochemical mechanisms for the scheduled synergism of (alpha S, 5S)-2 amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid and 5-fluorouracil in P388 leukemia.
    Ardalan B; Chandrasekaran B; Hrishikeshavan HJ
    Cancer Chemother Pharmacol; 1985; 15(1):44-8. PubMed ID: 2408773
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A new antitumor antimetabolite, (alphaS,5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (NSC-163501): antimicrobial reversal studies and preliminary evaluation against L1210 mouse leukemia in vivo.
    Hanka LJ; Martin DG; Neil GL
    Cancer Chemother Rep; 1973 Apr; 57(2):141-8. PubMed ID: 4200486
    [No Abstract]   [Full Text] [Related]  

  • 13. The inhibition of gamma-glutamyl transpeptidase and glutathione metabolism of isolated rat kidney cells by L-(alpha S, 5S)-alpha-amino-3-chloro-4, 5-dihydro-5-isoxazoleacetic acid (AT-125; NSC-163501).
    Reed DJ; Ellis WW; Meck RA
    Biochem Biophys Res Commun; 1980 Jun; 94(4):1273-7. PubMed ID: 6104962
    [No Abstract]   [Full Text] [Related]  

  • 14. Monocytoid differentiation of freshly isolated human myeloid leukemia cells and HL-60 cells induced by the glutamine antagonist acivicin.
    Nichols KE; Chitneni SR; Moore JO; Weinberg JB
    Blood; 1989 Oct; 74(5):1728-37. PubMed ID: 2790198
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enhancement of antitumor activity of glutamine antagonists 6-diazo-5-oxo-L-norleucine and acivicin in cell culture by glutaminase-asparaginase.
    Rosenfeld H; Roberts J
    Cancer Res; 1981 Apr; 41(4):1324-8. PubMed ID: 7214322
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Therapy for mouse tumors and human tumor xenografts with the antitumor antibiotic AT-125.
    Houchens DP; Ovejera AA; Sheridan MA; Johnson RK; Bogden AE; Neil GL
    Cancer Treat Rep; 1979 Mar; 63(3):473-6. PubMed ID: 427827
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biochemical pharmacology of acivicin in rat hepatoma cells.
    Lui MS; Kizaki H; Weber G
    Biochem Pharmacol; 1982 Nov; 31(21):3469-73. PubMed ID: 7150366
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of cell cycle progression of human pancreatic carcinoma cells in vitro by L-(alpha S, 5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid, Acivicin (NSC 163501).
    Meck RA; Clubb KJ; Allen LM; Yunis AA
    Cancer Res; 1981 Nov; 41(11 Pt 1):4547-53. PubMed ID: 7306976
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interaction of AT-125, (alpha S,5S)-amino-3-chloro-4,5-dihydroisoxazoleacetic acid, with bovine kidney gamma-glutamyl transpeptidase.
    Allen LM; Corrigan MV; Meinking T
    Chem Biol Interact; 1981 Jan; 33(2-3):361-5. PubMed ID: 6109574
    [No Abstract]   [Full Text] [Related]  

  • 20. Interaction of the antitumor drug, L-(alpha S, 5S)-alpha-amino-3-chloro-4,5-dihydro-5-isoxazoleacetic acid (AT-125) with renal brush border membranes. Specific labeling of gamma-glutamyl transpeptidase.
    Kozak EM; Tate SS
    FEBS Lett; 1980 Dec; 122(2):175-8. PubMed ID: 6110565
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 7.