BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 7575514)

  • 1. Heteroatom substitution shifts regioselectivity of lauric acid metabolism from omega-hydroxylation to (omega-1)-oxidation.
    Alterman MA; Chaurasia CS; Lu P; Hanzlik RP
    Biochem Biophys Res Commun; 1995 Sep; 214(3):1089-94. PubMed ID: 7575514
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of steric bulk and conformational rigidity on fatty acid omega hydroxylation by a cytochrome P450 4A1 fusion protein.
    Bambal RB; Hanzlik RP
    Arch Biochem Biophys; 1996 Oct; 334(1):59-66. PubMed ID: 8837739
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Biochemical characterization of lauric acid omega-hydroxylation by a CYP4A1/NADPH-cytochrome P450 reductase fusion protein.
    Chaurasia CS; Alterman MA; Lu P; Hanzlik RP
    Arch Biochem Biophys; 1995 Feb; 317(1):161-9. PubMed ID: 7872779
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vitro hydroxylation and epoxidation of some isomeric lauric acid analogs by rat liver microsomes. Identification of metabolites and effects of clofibrate or phenobarbital pretreatment.
    Boucher JL; Delaforge M; Salaün JP; Pinot F; Durst F; Pflieger P; Mioskowski C
    Drug Metab Dispos; 1996 Apr; 24(4):462-8. PubMed ID: 8801062
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Heme-coordinating analogs of lauric acid as inhibitors of fatty acid omega-hydroxylation.
    Lu P; Alterman MA; Chaurasia CS; Bambal RB; Hanzlik RP
    Arch Biochem Biophys; 1997 Jan; 337(1):1-7. PubMed ID: 8990261
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Omega- and (omega-1)-hydroxylation of lauric acid and arachidonic acid by rat renal cytochrome P-450.
    Imaoka S; Tanaka S; Funae Y
    Biochem Int; 1989 Apr; 18(4):731-40. PubMed ID: 2504167
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Hydrophobic side chain requirements for lauric acid and progesterone hydroxylation at amino acid 113 in cytochrome P450 2C2, a potential determinant of substrate specificity.
    Straub P; Johnson EF; Kemper B
    Arch Biochem Biophys; 1993 Nov; 306(2):521-7. PubMed ID: 8215458
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CYP4 isoform specificity in the omega-hydroxylation of phytanic acid, a potential route to elimination of the causative agent of Refsum's disease.
    Xu F; Ng VY; Kroetz DL; de Montellano PR
    J Pharmacol Exp Ther; 2006 Aug; 318(2):835-9. PubMed ID: 16707724
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Identification of CYP4A11 as the major lauric acid omega-hydroxylase in human liver microsomes.
    Powell PK; Wolf I; Lasker JM
    Arch Biochem Biophys; 1996 Nov; 335(1):219-26. PubMed ID: 8914854
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Alcohol consumption enhances fatty acid omega-oxidation, with a greater increase in male than in female rats.
    Ma X; Baraona E; Lieber CS
    Hepatology; 1993 Nov; 18(5):1247-53. PubMed ID: 8225232
    [TBL] [Abstract][Full Text] [Related]  

  • 11. P-450-dependent metabolism of lauric acid in alcoholic liver disease: comparison between rat liver and kidney microsomes.
    Amet Y; Lucas D; Zhang-Gouillon ZQ; French SW
    Alcohol Clin Exp Res; 1998 Apr; 22(2):455-62. PubMed ID: 9581653
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A novel rat hepatic clofibrate-inducible cytochrome P450 that is not a lauric acid hydroxylase.
    Swinney DC; Webb AS; Freedman R
    Biochem Pharmacol; 1991 Nov; 42(12):2341-9. PubMed ID: 1662512
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The effect of hypolipidemic agents on the hepatic microsomal drug-metabolizing enzyme system of the rat. Induction of cytochrome(s) P-450 with specificity toward terminal hydroxylation of lauric acid.
    Orton TC; Parker GL
    Drug Metab Dispos; 1982; 10(2):110-5. PubMed ID: 6124394
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Involvement of cytochrome P450 2E1 in the (omega-1)-hydroxylation of oleic acid in human and rat liver microsomes.
    Adas F; Berthou F; Picart D; Lozac'h P; Beaugé F; Amet Y
    J Lipid Res; 1998 Jun; 39(6):1210-9. PubMed ID: 9643352
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Active site structure and substrate specificity of cytochrome P450 4A1: steric control of ligand approach perpendicular to heme plane.
    Bambal RB; Hanzlik RP
    Biochem Biophys Res Commun; 1996 Feb; 219(2):445-9. PubMed ID: 8605007
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evidence that cytochrome P450 2E1 is involved in the (omega-1)-hydroxylation of lauric acid in rat liver microsomes.
    Amet Y; Berthou F; Goasduff T; Salaun JP; Le Breton L; Menez JF
    Biochem Biophys Res Commun; 1994 Sep; 203(2):1168-74. PubMed ID: 8093035
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oxidation of 1,8-cineole, the monoterpene cyclic ether originated from eucalyptus polybractea, by cytochrome P450 3A enzymes in rat and human liver microsomes.
    Miyazawa M; Shindo M; Shimada T
    Drug Metab Dispos; 2001 Feb; 29(2):200-5. PubMed ID: 11159812
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The regiospecific hydroxylation of lauric acid by rainbow trout (Oncorhynchus mykiss) cytochrome P450s.
    Buhler DR; Miranda CL; Deinzer ML; Griffin DA; Henderson MC
    Drug Metab Dispos; 1997 Oct; 25(10):1176-83. PubMed ID: 9321521
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation.
    Mani C; Gelboin HV; Park SS; Pearce R; Parkinson A; Kupfer D
    Drug Metab Dispos; 1993; 21(4):645-56. PubMed ID: 8104124
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of cytochrome P450 in oxazaphosphorine metabolism. Deactivation via N-dechloroethylation and activation via 4-hydroxylation catalyzed by distinct subsets of rat liver cytochromes P450.
    Yu L; Waxman DJ
    Drug Metab Dispos; 1996 Nov; 24(11):1254-62. PubMed ID: 8937861
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.