130 related articles for article (PubMed ID: 7577943)
1. The major, N2-Gua adduct of the (+)-anti-benzo[a]pyrene diol epoxide is capable of inducing G-->A and G-->C, in addition to G-->T, mutations.
Jelinsky SA; Liu T; Geacintov NE; Loechler EL
Biochemistry; 1995 Oct; 34(41):13545-53. PubMed ID: 7577943
[TBL] [Abstract][Full Text] [Related]
2. AP sites are not significantly involved in mutagenesis by the (+)-anti diol epoxide of benzo[a]pyrene: the complexity of its mutagenic specificity is likely to arise from adduct conformational polymorphism.
Drouin EE; Loechler EL
Biochemistry; 1993 Jul; 32(26):6555-62. PubMed ID: 7687146
[TBL] [Abstract][Full Text] [Related]
3. The major, N2-Gua adduct of the (+)-anti-benzo[a]pyrene diol epoxide can be unstable in double-stranded DNA.
Drouin EE; Lech J; Loechler EL
Biochemistry; 1995 Feb; 34(7):2251-9. PubMed ID: 7857936
[TBL] [Abstract][Full Text] [Related]
4. Mutagenesis by the (+)-anti-diol epoxide of benzo[a]pyrene: what controls mutagenic specificity?
Rodriguez H; Loechler EL
Biochemistry; 1993 Feb; 32(7):1759-69. PubMed ID: 8439538
[TBL] [Abstract][Full Text] [Related]
5. The major, N2-dG adduct of (+)-anti-B[a]PDE shows a dramatically different mutagenic specificity (predominantly, G --> A) in a 5'-CGT-3' sequence context.
Shukla R; Liu T; Geacintov NE; Loechler EL
Biochemistry; 1997 Aug; 36(33):10256-61. PubMed ID: 9254624
[TBL] [Abstract][Full Text] [Related]
6. Mutational specificity of the (+)-anti-diol epoxide of benzo[a]pyrene in a supF gene of an Escherichia coli plasmid: DNA sequence context influences hotspots, mutagenic specificity and the extent of SOS enhancement of mutagenesis.
Rodriguez H; Loechler EL
Carcinogenesis; 1993 Mar; 14(3):373-83. PubMed ID: 8453713
[TBL] [Abstract][Full Text] [Related]
7. Are base substitution and frameshift mutagenesis pathways interrelated? An analysis based upon studies of the frequencies and specificities of mutations induced by the (+)-anti diol epoxide of benzo[a]pyrene.
Rodriguez H; Loechler EL
Mutat Res; 1995 Jan; 326(1):29-37. PubMed ID: 7528883
[TBL] [Abstract][Full Text] [Related]
8. Sequence specific mutagenesis of the major (+)-anti-benzo[a]pyrene diol epoxide-DNA adduct at a mutational hot spot in vitro and in Escherichia coli cells.
Hanrahan CJ; Bacolod MD; Vyas RR; Liu T; Geacintov NE; Loechler EL; Basu AK
Chem Res Toxicol; 1997 Apr; 10(4):369-77. PubMed ID: 9114972
[TBL] [Abstract][Full Text] [Related]
9. The major, N2-dG adduct of (+)-anti-B[a]PDE induces G-->A mutations in a 5'-AGA-3' sequence context.
Shukla R; Geacintov NE; Loechler EL
Carcinogenesis; 1999 Feb; 20(2):261-8. PubMed ID: 10069463
[TBL] [Abstract][Full Text] [Related]
10. A role for DNA polymerase V in G --> T mutations from the major benzo[a]pyrene N2-dG adduct when studied in a 5'-TGT sequence in E. coli.
Yin J; Seo KY; Loechler EL
DNA Repair (Amst); 2004 Mar; 3(3):323-34. PubMed ID: 15177047
[TBL] [Abstract][Full Text] [Related]
11. Factors that influence the mutagenic patterns of DNA adducts from chemical carcinogens.
Seo KY; Jelinsky SA; Loechler EL
Mutat Res; 2000 Oct; 463(3):215-46. PubMed ID: 11018743
[TBL] [Abstract][Full Text] [Related]
12. Targeted A --> T and G --> T mutations induced by site-specific deoxyadenosine and deoxyguanosine adducts, respectively, from the (+)-anti-diol epoxide of dibenz[a,j]anthracene in M13mp7L2.
Min Z; Gill RD; Cortez C; Harvey RG; Loechler EL; DiGiovanni J
Biochemistry; 1996 Apr; 35(13):4128-38. PubMed ID: 8672448
[TBL] [Abstract][Full Text] [Related]
13. Construction of an Escherichia coli vector containing the major DNA adduct of activated benzo[a]pyrene at a defined site.
Benasutti M; Ezzedine ZD; Loechler EL
Chem Res Toxicol; 1988; 1(3):160-8. PubMed ID: 2979726
[TBL] [Abstract][Full Text] [Related]
14. Mutagenesis by (+)-anti-B[a]P-N2-Gua, the major adduct of activated benzo[a]pyrene, when studied in an Escherichia coli plasmid using site-directed methods.
Mackay W; Benasutti M; Drouin E; Loechler EL
Carcinogenesis; 1992 Aug; 13(8):1415-25. PubMed ID: 1499092
[TBL] [Abstract][Full Text] [Related]
15. Mutagenic potential of stereoisomeric bay region (+)- and (-)-cis-anti-benzo[a]pyrene diol epoxide-N2-2'-deoxyguanosine adducts in Escherichia coli and simian kidney cells.
Fernandes A; Liu T; Amin S; Geacintov NE; Grollman AP; Moriya M
Biochemistry; 1998 Jul; 37(28):10164-72. PubMed ID: 9665722
[TBL] [Abstract][Full Text] [Related]
16. Expression of human glutathione S-transferase P1 confers resistance to benzo[a]pyrene or benzo[a]pyrene-7,8-dihydrodiol mutagenesis, macromolecular alkylation and formation of stable N2-Gua-BPDE adducts in stably transfected V79MZ cells co-expressing hCYP1A1.
Kushman ME; Kabler SL; Fleming MH; Ravoori S; Gupta RC; Doehmer J; Morrow CS; Townsend AJ
Carcinogenesis; 2007 Jan; 28(1):207-14. PubMed ID: 16885195
[TBL] [Abstract][Full Text] [Related]
17. Induction of specific frameshift and base substitution events by benzo[a]pyrene diol epoxide in excision-repair-deficient Escherichia coli.
Bernelot-Moens C; Glickman BW; Gordon AJ
Carcinogenesis; 1990 May; 11(5):781-5. PubMed ID: 2110513
[TBL] [Abstract][Full Text] [Related]
18. Molecular modeling of the major adduct of (+)-anti-B[a]PDE (N2-dG) in the eight conformations and the five DNA sequences most relevant to base substitution mutagenesis.
Kozack RE; Loechler EL
Carcinogenesis; 1999 Jan; 20(1):85-94. PubMed ID: 9934854
[TBL] [Abstract][Full Text] [Related]
19. Molecular characterization of mutation and comparison of mutation profiles in the hprt gene of Chinese hamster ovary cells treated with benzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, 1-nitrobenzo[a]pyrene trans-7,8-diol-anti-9,10-epoxide, and 3-nitrobenzo[a]pyrene trans-7,8- diol-anti-9,10-epoxide.
Zhan DJ; Heflich RH; Fu PP
Environ Mol Mutagen; 1996; 27(1):19-29. PubMed ID: 8625944
[TBL] [Abstract][Full Text] [Related]
20. Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: similarities with the p53 mutation spectrum in smoking-associated lung cancers.
Yoon JH; Smith LE; Feng Z; Tang M; Lee CS; Pfeifer GP
Cancer Res; 2001 Oct; 61(19):7110-7. PubMed ID: 11585742
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
