BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 7579667)

  • 1. Production of monoclonal antibodies in COS and CHO cells.
    Trill JJ; Shatzman AR; Ganguly S
    Curr Opin Biotechnol; 1995 Oct; 6(5):553-60. PubMed ID: 7579667
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Attenuated glutamine synthetase as a selection marker in CHO cells to efficiently isolate highly productive stable cells for the production of antibodies and other biologics.
    Lin PC; Chan KF; Kiess IA; Tan J; Shahreel W; Wong SY; Song Z
    MAbs; 2019 Jul; 11(5):965-976. PubMed ID: 31043114
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The Augmenting Effects of the tDNA Insulator on Stable Expression of Monoclonal Antibody in Chinese Hamster Ovary Cells.
    Naderi F; Hashemi M; Bayat H; Mohammadian O; Pourmaleki E; Etemadzadeh MH; Rahimpour A
    Monoclon Antib Immunodiagn Immunother; 2018 Nov; 37(5):200-206. PubMed ID: 30362930
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Improving the efficiency of CHO cell line generation using glutamine synthetase gene knockout cells.
    Fan L; Kadura I; Krebs LE; Hatfield CC; Shaw MM; Frye CC
    Biotechnol Bioeng; 2012 Apr; 109(4):1007-15. PubMed ID: 22068567
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chinese hamster ovary K1 host cell enables stable cell line development for antibody molecules which are difficult to express in DUXB11-derived dihydrofolate reductase deficient host cell.
    Hu Z; Guo D; Yip SS; Zhan D; Misaghi S; Joly JC; Snedecor BR; Shen AY
    Biotechnol Prog; 2013; 29(4):980-5. PubMed ID: 23606666
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Lengthening of high-yield production levels of monoclonal antibody-producing Chinese hamster ovary cells by downregulation of breast cancer 1.
    Matsuyama R; Yamano N; Kawamura N; Omasa T
    J Biosci Bioeng; 2017 Mar; 123(3):382-389. PubMed ID: 27742176
    [TBL] [Abstract][Full Text] [Related]  

  • 7. A study of monoclonal antibody-producing CHO cell lines: what makes a stable high producer?
    Chusainow J; Yang YS; Yeo JH; Toh PC; Asvadi P; Wong NS; Yap MG
    Biotechnol Bioeng; 2009 Mar; 102(4):1182-96. PubMed ID: 18979540
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Optimized Selection Marker and CHO Host Cell Combinations for Generating High Monoclonal Antibody Producing Cell Lines.
    Yeo JHM; Ho SCL; Mariati M; Koh E; Tay SJ; Woen S; Zhang P; Yang Y
    Biotechnol J; 2017 Dec; 12(12):. PubMed ID: 29090854
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Proteomic analysis of CHO cell lines producing high and low quantities of a recombinant antibody before and after selection with methotrexate.
    Hausmann R; Chudobová I; Spiegel H; Schillberg S
    J Biotechnol; 2018 Jan; 265():65-69. PubMed ID: 29137976
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Gene amplification and vector engineering to achieve rapid and high-level therapeutic protein production using the Dhfr-based CHO cell selection system.
    Cacciatore JJ; Chasin LA; Leonard EF
    Biotechnol Adv; 2010; 28(6):673-81. PubMed ID: 20416368
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Generation of recombinant CHO(dhfr-) cell lines by single selection for dhfr+ transformants.
    Wernicke D; Will H
    Anal Biochem; 1992 May; 203(1):146-50. PubMed ID: 1524211
    [TBL] [Abstract][Full Text] [Related]  

  • 12. High level expression on a chimeric anti-ganglioside GD2 antibody: genomic kappa sequences improve expression in COS and CHO cells.
    Fouser LA; Swanberg SL; Lin BY; Benedict M; Kelleher K; Cumming DA; Riedel GE
    Biotechnology (N Y); 1992 Oct; 10(10):1121-7. PubMed ID: 1382457
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Generation of stable cell lines by site-specific integration of transgenes into engineered Chinese hamster ovary strains using an FLP-FRT system.
    Zhou H; Liu ZG; Sun ZW; Huang Y; Yu WY
    J Biotechnol; 2010 May; 147(2):122-9. PubMed ID: 20371256
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Significantly improvement of antibody expression level in CHO cells through downregulation of the DHFR gene in expression vector].
    Bai Y; Wang Y; Zhang HR; Zhou LJ; Lu YQ; Yu LZ
    Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi; 2003 Jan; 19(1):62-4, 67. PubMed ID: 15132910
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Early prediction of instability of Chinese hamster ovary cell lines expressing recombinant antibodies and antibody-fusion proteins.
    Dorai H; Corisdeo S; Ellis D; Kinney C; Chomo M; Hawley-Nelson P; Moore G; Betenbaugh MJ; Ganguly S
    Biotechnol Bioeng; 2012 Apr; 109(4):1016-30. PubMed ID: 22068683
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Generation of high-producing cell lines by overexpression of cell division cycle 25 homolog A in Chinese hamster ovary cells.
    Lee KH; Tsutsui T; Honda K; Asano R; Kumagai I; Ohtake H; Omasa T
    J Biosci Bioeng; 2013 Dec; 116(6):754-60. PubMed ID: 23810665
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Expression of chimeric antibody in mammalian cells using dicistronic expression vector.
    Xiong KH; Liang QC; Xiong H; Zou CX; Gao GD; Zhao ZW; Zhang H
    Biotechnol Lett; 2005 Nov; 27(21):1713-7. PubMed ID: 16247680
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Comparison of expression of a humanized monoclonal antibody in mouse NSO myeloma cells and Chinese hamster ovary cells.
    Peakman TC; Worden J; Harris RH; Cooper H; Tite J; Page MJ; Gewert DR; Bartholemew M; Crowe JS; Brett S
    Hum Antibodies Hybridomas; 1994; 5(1-2):65-74. PubMed ID: 7532024
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A mechanistic understanding of production instability in CHO cell lines expressing recombinant monoclonal antibodies.
    Kim M; O'Callaghan PM; Droms KA; James DC
    Biotechnol Bioeng; 2011 Oct; 108(10):2434-46. PubMed ID: 21538334
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Key determinants in the occurrence of clonal variation in humanized antibody expression of cho cells during dihydrofolate reductase mediated gene amplification.
    Kim NS; Byun TH; Lee GM
    Biotechnol Prog; 2001; 17(1):69-75. PubMed ID: 11170482
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.