These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

131 related articles for article (PubMed ID: 7582940)

  • 21. 1,2,9,9a-Tetrahydrocyclopropa[c]benz[e]indol-4-one (CBI) analogs of CC-1065 and the duocarmycins: synthesis and evaluation.
    Boger DL; Yun W; Han N
    Bioorg Med Chem; 1995 Nov; 3(11):1429-53. PubMed ID: 8634824
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Substituent effects within the DNA binding subunit of CBI analogues of the duocarmycins and CC-1065.
    Boger DL; Stauffer F; Hedrick MP
    Bioorg Med Chem Lett; 2001 Aug; 11(15):2021-4. PubMed ID: 11454471
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Stability and DNA alkylation rates of the simplest functional analogues of CC-1065, para-hydroxy and para-amino phenethyl bromides.
    Shalders RL; Blanch G; Brown CL; Young DJ; Prakash AS
    Chem Biol Interact; 1999 Jan; 117(1):83-94. PubMed ID: 10190546
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The minor groove covalent reactive drugs anthramycin and (+)-CC-1065 and their interstrand cross-linking derivatives.
    Hurley LH
    IARC Sci Publ; 1994; (125):295-312. PubMed ID: 7806319
    [No Abstract]   [Full Text] [Related]  

  • 25. (+)-CC-1065 as a structural probe of Mu transposase-induced bending of DNA: overcoming limitations of hydroxyl-radical footprinting.
    Ding ZM; Harshey RM; Hurley LH
    Nucleic Acids Res; 1993 Sep; 21(18):4281-7. PubMed ID: 8414983
    [TBL] [Abstract][Full Text] [Related]  

  • 26. DNA interstrand cross-linking, DNA sequence specificity, and induced conformational changes produced by a dimeric analog of (+)-CC-1065.
    Ding ZM; Hurley LH
    Anticancer Drug Des; 1991 Nov; 6(5):427-52. PubMed ID: 1662513
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Molecular basis for sequence-specific DNA alkylation by CC-1065.
    Hurley LH; Lee CS; McGovren JP; Warpehoski MA; Mitchell MA; Kelly RC; Aristoff PA
    Biochemistry; 1988 May; 27(10):3886-92. PubMed ID: 3408734
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Calf thymus DNA binding/bonding properties of CC-1065 and analogs as related to their biological activities and toxicities.
    Krueger WC; Prairie MD
    Chem Biol Interact; 1992 Mar; 82(1):31-46. PubMed ID: 1312395
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Catalysis of the CC-1065 and duocarmycin DNA alkylation reaction: DNA binding induced conformational change in the agent results in activation.
    Boger DL; Garbaccio RM
    Bioorg Med Chem; 1997 Feb; 5(2):263-76. PubMed ID: 9061191
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Alkylation of guanine and cytosine in DNA by bizelesin. Evidence for a covalent immobilization leading to a proximity-driven alkylation of normally unreactive bases by a (+)-CC-1065 cross-linking compound.
    Sun D; Park HJ; Hurley LH
    Chem Res Toxicol; 1993; 6(6):889-94. PubMed ID: 8117929
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Synthesis and evaluation of a series of C3-substituted CBI analogues of CC-1065 and the duocarmycins.
    Boger DL; Brunette SR; Garbaccio RM
    J Org Chem; 2001 Jul; 66(15):5163-73. PubMed ID: 11463270
    [TBL] [Abstract][Full Text] [Related]  

  • 32. DNA sequence recognition by the antitumor antibiotic CC-1065 and analogs of CC-1065.
    Krueger WC; Hatzenbuhler NT; Prairie MD; Shea MH
    Chem Biol Interact; 1991; 79(3):265-86. PubMed ID: 1913973
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Minor groove DNA alkylation directed by major groove triplex forming oligodeoxyribonucleotides.
    Lukhtanov EA; Mills AG; Kutyavin IV; Gorn VV; Reed MW; Meyer RB
    Nucleic Acids Res; 1997 Dec; 25(24):5077-84. PubMed ID: 9396819
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Reaction of the antitumor antibiotic CC-1065 with DNA. Location of the site of thermally induced strand breakage and analysis of DNA sequence specificity.
    Reynolds VL; Molineux IJ; Kaplan DJ; Swenson DH; Hurley LH
    Biochemistry; 1985 Oct; 24(22):6228-37. PubMed ID: 3002434
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Efficient guanine alkylation through cooperative heterodimeric formation of duocarmycin A and distamycin A.
    Isomura M; Sugiyama H; Saito I
    Nucleic Acids Symp Ser; 1995; (34):47-8. PubMed ID: 8841545
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Recent developments in sequence selective minor groove DNA effectors.
    Reddy BS; Sharma SK; Lown JW
    Curr Med Chem; 2001 Apr; 8(5):475-508. PubMed ID: 11281837
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Total synthesis and biological properties of novel antineoplastic (chloromethyl)furanoindolines: an asymmetric hydroboration mediated synthesis of the alkylation subunits.
    Mohamadi F; Spees MM; Staten GS; Marder P; Kipka JK; Johnson DA; Boger DL; Zarrinmayeh H
    J Med Chem; 1994 Jan; 37(2):232-9. PubMed ID: 8295210
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Systematic exploration of the structural features of yatakemycin impacting DNA alkylation and biological activity.
    Tichenor MS; MacMillan KS; Trzupek JD; Rayl TJ; Hwang I; Boger DL
    J Am Chem Soc; 2007 Sep; 129(35):10858-69. PubMed ID: 17691783
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Synthesis and biochemical evaluation of the CBI-PDE-I-dimer, a benzannelated analog of (+)-CC-1065 that also produces delayed toxicity in mice.
    Aristoff PA; Johnson PD; Sun D; Hurley LH
    J Med Chem; 1993 Jul; 36(14):1956-63. PubMed ID: 8336335
    [TBL] [Abstract][Full Text] [Related]  

  • 40. (+)-CC-1065 produces bending of DNA that appears to resemble adenine/thymine tracts.
    Lin CH; Sun DY; Hurley LH
    Chem Res Toxicol; 1991; 4(1):21-6. PubMed ID: 1655087
    [No Abstract]   [Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.