126 related articles for article (PubMed ID: 7586950)
1. Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo.
Mitra AK; Thummel KE; Kalhorn TF; Kharasch ED; Unadkat JD; Slattery JT
Clin Pharmacol Ther; 1995 Nov; 58(5):556-66. PubMed ID: 7586950
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of triazolam clearance by macrolide antimicrobial agents: in vitro correlates and dynamic consequences.
Greenblatt DJ; von Moltke LL; Harmatz JS; Counihan M; Graf JA; Durol AL; Mertzanis P; Duan SX; Wright CE; Shader RI
Clin Pharmacol Ther; 1998 Sep; 64(3):278-85. PubMed ID: 9757151
[TBL] [Abstract][Full Text] [Related]
3. Lack of correlation between in vitro and in vivo studies on the effects of tangeretin and tangerine juice on midazolam hydroxylation.
Backman JT; Mäenpää J; Belle DJ; Wrighton SA; Kivistö KT; Neuvonen PJ
Clin Pharmacol Ther; 2000 Apr; 67(4):382-90. PubMed ID: 10801247
[TBL] [Abstract][Full Text] [Related]
4. Metabolic interactions of putative cytochrome P4503A substrates with alternative pathways of dapsone metabolism in human liver microsomes.
Irshaid Y; Branch RA; Adedoyin A
Drug Metab Dispos; 1996 Feb; 24(2):164-171. PubMed ID: 8742227
[TBL] [Abstract][Full Text] [Related]
5. The effect of clarithromycin, fluconazole, and rifabutin on dapsone hydroxylamine formation in individuals with human immunodeficiency virus infection (AACTG 283).
Winter HR; Trapnell CB; Slattery JT; Jacobson M; Greenspan DL; Hooton TM; Unadkat JD
Clin Pharmacol Ther; 2004 Dec; 76(6):579-87. PubMed ID: 15592329
[TBL] [Abstract][Full Text] [Related]
6. Identification of the human P-450 enzymes responsible for the sulfoxidation and thiono-oxidation of diethyldithiocarbamate methyl ester: role of P-450 enzymes in disulfiram bioactivation.
Madan A; Parkinson A; Faiman MD
Alcohol Clin Exp Res; 1998 Sep; 22(6):1212-9. PubMed ID: 9756035
[TBL] [Abstract][Full Text] [Related]
7. Role of cytochrome P450 2E1 in the metabolism of 1,1,2,3,3,3-hexafluoropropyl methyl ether.
Köster U; Speerschneider P; Kerssebaum R; Wittmann H; Dekant W
Drug Metab Dispos; 1994; 22(5):667-72. PubMed ID: 7835215
[TBL] [Abstract][Full Text] [Related]
8. Inhibition of sulfamethoxazole hydroxylamine formation by fluconazole in human liver microsomes and healthy volunteers.
Mitra AK; Thummel KE; Kalhorn TF; Kharasch ED; Unadkat JD; Slattery JT
Clin Pharmacol Ther; 1996 Mar; 59(3):332-40. PubMed ID: 8653996
[TBL] [Abstract][Full Text] [Related]
9. Evidence that the biotransformation of dapsone and monoacetyldapsone to their respective hydroxylamine metabolites in rat liver microsomes is mediated by cytochrome P450 2C6/2C11 and 3A1.
Vage C; Svensson CK
Drug Metab Dispos; 1994; 22(4):572-7. PubMed ID: 7956732
[TBL] [Abstract][Full Text] [Related]
10. Role of human microsomal and human complementary DNA-expressed cytochromes P4501A2 and P4503A4 in the bioactivation of aflatoxin B1.
Gallagher EP; Wienkers LC; Stapleton PL; Kunze KL; Eaton DL
Cancer Res; 1994 Jan; 54(1):101-8. PubMed ID: 8261428
[TBL] [Abstract][Full Text] [Related]
11. Ropivacaine, a new amide-type local anesthetic agent, is metabolized by cytochromes P450 1A and 3A in human liver microsomes.
Ekström G; Gunnarsson UB
Drug Metab Dispos; 1996 Sep; 24(9):955-61. PubMed ID: 8886604
[TBL] [Abstract][Full Text] [Related]
12. Involvement of human liver cytochrome P450 3A in vinblastine metabolism: drug interactions.
Zhou-Pan XR; Sérée E; Zhou XJ; Placidi M; Maurel P; Barra Y; Rahmani R
Cancer Res; 1993 Nov; 53(21):5121-6. PubMed ID: 8221648
[TBL] [Abstract][Full Text] [Related]
13. Effect of CYP3A inhibition on vesnarinone metabolism in humans.
Wandel C; Lang CC; Cowart DC; Girard AF; Bramer S; Flockhart DA; Wood AJ
Clin Pharmacol Ther; 1998 May; 63(5):506-11. PubMed ID: 9630823
[TBL] [Abstract][Full Text] [Related]
14. Reduction of sulfamethoxazole and dapsone hydroxylamines by a microsomal enzyme system purified from pig liver and pig and human liver microsomes.
Clement B; Behrens D; Amschler J; Matschke K; Wolf S; Havemeyer A
Life Sci; 2005 May; 77(2):205-19. PubMed ID: 15862605
[TBL] [Abstract][Full Text] [Related]
15. Oxidation of 1,8-cineole, the monoterpene cyclic ether originated from eucalyptus polybractea, by cytochrome P450 3A enzymes in rat and human liver microsomes.
Miyazawa M; Shindo M; Shimada T
Drug Metab Dispos; 2001 Feb; 29(2):200-5. PubMed ID: 11159812
[TBL] [Abstract][Full Text] [Related]
16. Single-dose disulfiram inhibition of chlorzoxazone metabolism: a clinical probe for P450 2E1.
Kharasch ED; Thummel KE; Mhyre J; Lillibridge JH
Clin Pharmacol Ther; 1993 Jun; 53(6):643-50. PubMed ID: 8513656
[TBL] [Abstract][Full Text] [Related]
17. The role of cytochrome P450 2E1 in the species-dependent biotransformation of 1,2-dichloro-1,1,2-trifluoroethane in rats and mice.
Dekant W; Assmann M; Urban G
Toxicol Appl Pharmacol; 1995 Dec; 135(2):200-7. PubMed ID: 8545828
[TBL] [Abstract][Full Text] [Related]
18. Both cytochromes P450 2E1 and 3A are involved in the O-hydroxylation of p-nitrophenol, a catalytic activity known to be specific for P450 2E1.
Zerilli A; Ratanasavanh D; Lucas D; Goasduff T; Dréano Y; Menard C; Picart D; Berthou F
Chem Res Toxicol; 1997 Oct; 10(10):1205-12. PubMed ID: 9348445
[TBL] [Abstract][Full Text] [Related]
19. Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: molecular base for interaction potential and variable disposition of active metabolites.
Botsch S; Gautier JC; Beaune P; Eichelbaum M; Kroemer HK
Mol Pharmacol; 1993 Jan; 43(1):120-6. PubMed ID: 8423765
[TBL] [Abstract][Full Text] [Related]
20. CYP2C8/9 mediate dapsone N-hydroxylation at clinical concentrations of dapsone.
Winter HR; Wang Y; Unadkat JD
Drug Metab Dispos; 2000 Aug; 28(8):865-8. PubMed ID: 10901692
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
