205 related articles for article (PubMed ID: 7609078)
1. Retroviral integration at the Evi-2 locus in BXH-2 myeloid leukemia cell lines disrupts Nf1 expression without changes in steady-state Ras-GTP levels.
Largaespada DA; Shaughnessy JD; Jenkins NA; Copeland NG
J Virol; 1995 Aug; 69(8):5095-102. PubMed ID: 7609078
[TBL] [Abstract][Full Text] [Related]
2. Frequent disruption of the Nf1 gene by a novel murine AIDS virus-related provirus in BXH-2 murine myeloid lymphomas.
Cho BC; Shaughnessy JD; Largaespada DA; Bedigian HG; Buchberg AM; Jenkins NA; Copeland NG
J Virol; 1995 Nov; 69(11):7138-46. PubMed ID: 7474134
[TBL] [Abstract][Full Text] [Related]
3. Genetic analysis is consistent with the hypothesis that NF1 limits myeloid cell growth through p21ras.
Kalra R; Paderanga DC; Olson K; Shannon KM
Blood; 1994 Nov; 84(10):3435-9. PubMed ID: 7949098
[TBL] [Abstract][Full Text] [Related]
4. Retroviral integration at the Epi1 locus cooperates with Nf1 gene loss in the progression to acute myeloid leukemia.
Blaydes SM; Kogan SC; Truong BT; Gilbert DJ; Jenkins NA; Copeland NG; Largaespada DA; Brannan CI
J Virol; 2001 Oct; 75(19):9427-34. PubMed ID: 11533205
[TBL] [Abstract][Full Text] [Related]
5. Evi-2, a common integration site involved in murine myeloid leukemogenesis.
Buchberg AM; Bedigian HG; Jenkins NA; Copeland NG
Mol Cell Biol; 1990 Sep; 10(9):4658-66. PubMed ID: 2167436
[TBL] [Abstract][Full Text] [Related]
6. Detection of integrated murine leukemia viruses in a mouse model of acute myeloid leukemia by fluorescence in situ hybridization combined with tyramide signal amplification.
Acar H; Copeland NG; Gilbert DJ; Jenkins NA; Largaespada DA
Cancer Genet Cytogenet; 2000 Aug; 121(1):44-51. PubMed ID: 10958940
[TBL] [Abstract][Full Text] [Related]
7. Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells.
Bollag G; Clapp DW; Shih S; Adler F; Zhang YY; Thompson P; Lange BJ; Freedman MH; McCormick F; Jacks T; Shannon K
Nat Genet; 1996 Feb; 12(2):144-8. PubMed ID: 8563751
[TBL] [Abstract][Full Text] [Related]
8. Retroviral insertions in the CB-1/Fim-3 common site of integration activate expression of the Evi-1 gene.
Bartholomew C; Morishita K; Askew D; Buchberg A; Jenkins NA; Copeland NG; Ihle JN
Oncogene; 1989 May; 4(5):529-34. PubMed ID: 2542863
[TBL] [Abstract][Full Text] [Related]
9. Mrvi1, a common MRV integration site in BXH2 myeloid leukemias, encodes a protein with homology to a lymphoid-restricted membrane protein Jaw1.
Shaughnessy JD; Largaespada DA; Tian E; Fletcher CF; Cho BC; Vyas P; Jenkins NA; Copeland NG
Oncogene; 1999 Mar; 18(12):2069-84. PubMed ID: 10321731
[TBL] [Abstract][Full Text] [Related]
10. The GAP-related domain of neurofibromin attenuates proliferation and downregulates N- and K-Ras activation in Nf1-negative AML cells.
Morgan KJ; Rowley MA; Wiesner SM; Hasz DE; Van Ness B; Largaespada DA
Leuk Res; 2007 Aug; 31(8):1107-13. PubMed ID: 17222906
[TBL] [Abstract][Full Text] [Related]
11. Retroviral insertions 90 kilobases proximal to the Evi-1 myeloid transforming gene activate transcription from the normal promoter.
Bartholomew C; Ihle JN
Mol Cell Biol; 1991 Apr; 11(4):1820-8. PubMed ID: 1848663
[TBL] [Abstract][Full Text] [Related]
12. Inhibition of Ras/Raf interaction by anti-oncogenic mutants of neurofibromin, the neurofibromatosis type 1 (NF1) gene product, in cell-free systems.
Mori S; Satoh T; Koide H; Nakafuku M; Villafranca E; Kaziro Y
J Biol Chem; 1995 Dec; 270(48):28834-8. PubMed ID: 7499408
[TBL] [Abstract][Full Text] [Related]
13. Ras-GTP levels are elevated in human NF1 peripheral nerve tumors.
Guha A; Lau N; Huvar I; Gutmann D; Provias J; Pawson T; Boss G
Oncogene; 1996 Feb; 12(3):507-13. PubMed ID: 8637706
[TBL] [Abstract][Full Text] [Related]
14. Ras-GTP regulation is not altered in cultured melanocytes with reduced levels of neurofibromin derived from patients with neurofibromatosis 1 (NF1).
Griesser J; Kaufmann D; Eisenbarth I; Bäuerle C; Krone W
Biol Chem Hoppe Seyler; 1995 Feb; 376(2):91-101. PubMed ID: 7794530
[TBL] [Abstract][Full Text] [Related]
15. Neurofibromatosis type 1 gene mutations in neuroblastoma.
The I; Murthy AE; Hannigan GE; Jacoby LB; Menon AG; Gusella JF; Bernards A
Nat Genet; 1993 Jan; 3(1):62-6. PubMed ID: 8490657
[TBL] [Abstract][Full Text] [Related]
16. Abnormal regulation of mammalian p21ras contributes to malignant tumor growth in von Recklinghausen (type 1) neurofibromatosis.
DeClue JE; Papageorge AG; Fletcher JA; Diehl SR; Ratner N; Vass WC; Lowy DR
Cell; 1992 Apr; 69(2):265-73. PubMed ID: 1568246
[TBL] [Abstract][Full Text] [Related]
17. Mutational analysis of N-RAS and GAP-related domain of the neurofibromatosis type 1 gene in chronic myelogenous leukemia.
Garicochea B; Giorgi R; Odone VF; Dorlhiac-Llacer PE; Bendit I
Leuk Res; 1998 Nov; 22(11):1003-7. PubMed ID: 9783802
[TBL] [Abstract][Full Text] [Related]
18. Inactivation of the NF1 gene in human melanoma and neuroblastoma cell lines without impaired regulation of GTP.Ras.
Johnson MR; Look AT; DeClue JE; Valentine MB; Lowy DR
Proc Natl Acad Sci U S A; 1993 Jun; 90(12):5539-43. PubMed ID: 8516298
[TBL] [Abstract][Full Text] [Related]
19. The Ras inhibitor farnesylthiosalicylic acid as a potential therapy for neurofibromatosis type 1.
Barkan B; Starinsky S; Friedman E; Stein R; Kloog Y
Clin Cancer Res; 2006 Sep; 12(18):5533-42. PubMed ID: 17000690
[TBL] [Abstract][Full Text] [Related]
20. Nf1 deficiency causes Ras-mediated granulocyte/macrophage colony stimulating factor hypersensitivity and chronic myeloid leukaemia.
Largaespada DA; Brannan CI; Jenkins NA; Copeland NG
Nat Genet; 1996 Feb; 12(2):137-43. PubMed ID: 8563750
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
