BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 7616444)

  • 1. An inhibitor of leukocyte elastase prevents immune complex-mediated hemorrhage in the rat lung.
    Fletcher DS; Osinga DG; Keenan K; Bonney RJ; Doherty JB; Finke PE; Shah SK; Davies P
    J Pharmacol Exp Ther; 1995 Jul; 274(1):548-54. PubMed ID: 7616444
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A comparison of alpha 1-proteinase inhibitor methoxysuccinyl-Ala-Ala-Pro-Val-chloromethylketone and specific beta-lactam inhibitors in an acute model of human polymorphonuclear leukocyte elastase-induced lung hemorrhage in the hamster.
    Fletcher DS; Osinga DG; Hand KM; Dellea PS; Ashe BM; Mumford RA; Davies P; Hagmann W; Finke PE; Doherty JB
    Am Rev Respir Dis; 1990 Mar; 141(3):672-7. PubMed ID: 2310097
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pharmacological profile of the substituted beta-lactam L-659,286: a member of a new class of human PMN elastase inhibitors.
    Bonney RJ; Ashe B; Maycock A; Dellea P; Hand K; Osinga D; Fletcher D; Mumford R; Davies P; Frankenfield D
    J Cell Biochem; 1989 Jan; 39(1):47-53. PubMed ID: 2497109
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pharmacology of N-[4-(4-morpholinylcarbonyl)benzoyl]-L-valyl-N- [3,3,4,4,4-pentafluoro-1-(1-methylethyl)-2-oxobutyl]-L-prolinamide (MDL 101,146): a potent orally active inhibitor of human neutrophil elastase.
    Durham SL; Hare CM; Angelastro MR; Burkhart JP; Koehl JR; Marquart AL; Mehdi S; Peet NP; Janusz MJ
    J Pharmacol Exp Ther; 1994 Jul; 270(1):185-91. PubMed ID: 8035315
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reversible lung neutrophil accumulation can cause lung injury by elastase-mediated mechanisms.
    Anderson BO; Brown JM; Bensard DD; Grosso MA; Banerjee A; Patt A; Whitman GJ; Harken AH
    Surgery; 1990 Aug; 108(2):262-7; discussion 267-8. PubMed ID: 2166356
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 5-Methyl-4H-3,1-benzoxazin-4-one derivatives: specific inhibitors of human leukocyte elastase.
    Uejima Y; Kokubo M; Oshida J; Kawabata H; Kato Y; Fujii K
    J Pharmacol Exp Ther; 1993 May; 265(2):516-23. PubMed ID: 8496803
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neutrophil recruitment into the lungs is associated with increased lung elastase burden, decreased lung elastin, and emphysema in alpha 1 proteinase inhibitor-deficient mice.
    Cavarra E; Martorana PA; Gambelli F; de Santi M; van Even P; Lungarella G
    Lab Invest; 1996 Aug; 75(2):273-80. PubMed ID: 8765327
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacological evaluation of selected, orally active, peptidyl inhibitors of human neutrophil elastase.
    Janusz MJ; Durham SL; Hare CM; Geary JL; Mandagere AK; Poole JC; Thompson TN; Xu D; Anagelastro MR; Burkhart JP
    J Pharmacol Exp Ther; 1995 Dec; 275(3):1233-8. PubMed ID: 8531086
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Dual inhibition of human leukocyte elastase and lipid peroxidation: in vitro and in vivo activities of azabicyclo[2.2.2]octane and perhydroindole derivatives.
    Portevin B; Lonchampt M; Canet E; De Nanteuil G
    J Med Chem; 1997 Jun; 40(12):1906-18. PubMed ID: 9191969
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Role of polymorphonuclear leukocytes in connective tissue breakdown during the reverse passive Arthus reaction.
    Fletcher DS; Osinga D; Bonney RJ
    Biochem Pharmacol; 1986 Aug; 35(15):2601-6. PubMed ID: 3017358
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The effect of the specific elastase inhibitor, alanyl alanyl prolyl alanine chloromethylketone, on elastase-induced emphysema.
    Kleinerman J; Ranga V; Rynbrandt D; Sorensen J; Powers JC
    Am Rev Respir Dis; 1980 Feb; 121(2):381-7. PubMed ID: 6899738
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The role of lysosomal elastase in the digestion of Escherichia coli proteins by human polymorphonuclear leukocytes: experiments with living leukocytes.
    Blondin J; Janoff A
    J Clin Invest; 1976 Oct; 58(4):971-9. PubMed ID: 787011
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chemical, biochemical, pharmacokinetic, and biological properties of L-680,833: a potent, orally active monocyclic beta-lactam inhibitor of human polymorphonuclear leukocyte elastase.
    Doherty JB; Shah SK; Finke PE; Dorn CP; Hagmann WK; Hale JJ; Kissinger AL; Thompson KR; Brause K; Chandler GO
    Proc Natl Acad Sci U S A; 1993 Sep; 90(18):8727-31. PubMed ID: 8378355
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [The damaging effect of activated human neutrophils on isolated perfused rat lungs--the role of elastase].
    Guo Z; Zhu Y; Yan Y; Xi P
    Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 1995 Apr; 17(2):104-8. PubMed ID: 7656388
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Potency of truncated secretory leukoprotease inhibitor assessed in acute lung injury models in hamsters.
    Mitsuhashi H; Asano S; Nonaka T; Masuda K; Kiyoki M
    J Pharmacol Exp Ther; 1997 Aug; 282(2):1005-10. PubMed ID: 9262369
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DNase I acutely increases cystic fibrosis sputum elastase activity and its potential to induce lung hemorrhage in mice.
    Cantin AM
    Am J Respir Crit Care Med; 1998 Feb; 157(2):464-9. PubMed ID: 9476859
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition by elastase inhibitors of the formyl Met Leu Phe-induced chemotaxis of rat polymorphonuclear leukocytes.
    Hornebeck W; Soleilhac JM; Tixier JM; Moczar E; Robert L
    Cell Biochem Funct; 1987 Apr; 5(2):113-22. PubMed ID: 3495371
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biochemical and pharmacological activities of SR 26831, a potent and selective elastase inhibitor.
    Herbert JM; Frehel D; Rosso MP; Seban E; Castet C; Pepin O; Maffrand JP; Le Fur G
    J Pharmacol Exp Ther; 1992 Feb; 260(2):809-16. PubMed ID: 1738126
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Activation of polymorphonuclear leukocytes in oleic acid-induced lung injury.
    Moriuchi H; Zaha M; Fukumoto T; Yuizono T
    Intensive Care Med; 1998 Jul; 24(7):709-15. PubMed ID: 9722042
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The elastase/alpha 1-proteinase inhibitor balance in the lung. A review.
    Virca GD; Schnebli HP
    Schweiz Med Wochenschr; 1984 Jun; 114(25):895-8. PubMed ID: 6379867
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.