These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 7617545)

  • 1. Distribution of all-trans-, 13-cis- and 9-cis-retinoic acid to whole rat embryos and maternal serum following oral administration of a teratogenic dose of all-trans-retinoic acid.
    Ward SJ; Morriss-Kay GM
    Pharmacol Toxicol; 1995 Mar; 76(3):196-201. PubMed ID: 7617545
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparative teratology and transplacental pharmacokinetics of all-trans-retinoic acid, 13-cis-retinoic acid, and retinyl palmitate following daily administrations in rats.
    Collins MD; Tzimas G; Hummler H; Bürgin H; Nau H
    Toxicol Appl Pharmacol; 1994 Jul; 127(1):132-44. PubMed ID: 8048045
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The high sensitivity of the rabbit to the teratogenic effects of 13-cis-retinoic acid (isotretinoin) is a consequence of prolonged exposure of the embryo to 13-cis-retinoic acid and 13-cis-4-oxo-retinoic acid, and not of isomerization to all-trans-retinoic acid.
    Tzimas G; Bürgin H; Collins MD; Hummler H; Nau H
    Arch Toxicol; 1994; 68(2):119-28. PubMed ID: 8179481
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Retinoid metabolism and transplacental pharmacokinetics in the cynomolgus monkey following a nonteratogenic dosing regimen with all-trans-retinoic acid.
    Tzimas G; Nau H; Hendrickx AG; Peterson PE; Hummler H
    Teratology; 1996 Nov; 54(5):255-65. PubMed ID: 9035347
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Embryonic subcellular distribution of 13-cis- and all-trans-retinoic acid indicates differential cytosolic/nuclear localization.
    Rühl R; Plum C; Elmazar MM; Nau H
    Toxicol Sci; 2001 Sep; 63(1):82-9. PubMed ID: 11509747
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Distribution, teratogenicity, and embryonic delivered dose of retinoid Ro 23-9223.
    Willhite CC; Lovey A; Eckhoff C
    Toxicol Appl Pharmacol; 2000 Apr; 164(2):171-5. PubMed ID: 10764630
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Single versus multiple dose administration of all-trans-retinoic acid during organogenesis: differential metabolism and transplacental kinetics in rat and rabbit.
    Collins MD; Tzimas G; Bürgin H; Hummler H; Nau H
    Toxicol Appl Pharmacol; 1995 Jan; 130(1):9-18. PubMed ID: 7839374
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Low teratogenicity of 13-cis-retinoic acid (isotretinoin) in the mouse corresponds to low embryo concentrations during organogenesis: comparison to the all-trans isomer.
    Kraft JC; Kochhar DM; Scott WJ; Nau H
    Toxicol Appl Pharmacol; 1987 Mar; 87(3):474-82. PubMed ID: 3470977
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Teratogenicity and placental transfer of all-trans-, 13-cis-, 4-oxo-all-trans-, and 4-oxo-13-cis-retinoic acid after administration of a low oral dose during organogenesis in mice.
    Creech Kraft J; Löfberg B; Chahoud I; Bochert G; Nau H
    Toxicol Appl Pharmacol; 1989 Aug; 100(1):162-76. PubMed ID: 2763297
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Pharmacokinetic assessment of teratologically effective concentrations of an endogenous retinoic acid metabolite.
    Satre MA; Penner JD; Kochhar DM
    Teratology; 1989 Apr; 39(4):341-8. PubMed ID: 2749577
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Placental transfer and developmental effects of 9-cis retinoic acid in mice.
    Kochhar DM; Jiang H; Penner JD; Heyman RA
    Teratology; 1995 Apr; 51(4):257-65. PubMed ID: 7570368
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Maternal toxicokinetics, metabolism, and embryo exposure following a teratogenic dosing regimen with 13-cis-retinoic acid (isotretinoin) in the cynomolgus monkey.
    Hummler H; Hendrickx AG; Nau H
    Teratology; 1994 Sep; 50(3):184-93. PubMed ID: 7871482
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Correlations between conceptal concentrations of all-trans-retinoic acid and dysmorphogenesis after microinjections of all-trans-retinoic acid, 13-cis-retinoic acid, all-trans-retinoyl-beta-glucuronide, or retinol in cultured whole rat embryos.
    Kraft JC; Juchau MR
    Drug Metab Dispos; 1992; 20(2):218-25. PubMed ID: 1352213
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Embryotoxic doses of vitamin A to rabbits result in low plasma but high embryonic concentrations of all-trans-retinoic acid: risk of vitamin A exposure in humans.
    Tzimas G; Collins MD; Bürgin H; Hummler H; Nau H
    J Nutr; 1996 Sep; 126(9):2159-71. PubMed ID: 8814204
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Embryotoxicity and teratogenicity of topical retinoic acid.
    Nau H
    Skin Pharmacol; 1993; 6 Suppl 1():35-44. PubMed ID: 8142110
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Simultaneous quantification of various retinoids by high performance liquid chromatography: its relevance to alcohol research.
    Yokoyama H; Matsumoto M; Shiraishi H; Ishii H
    Alcohol Clin Exp Res; 2000 Apr; 24(4 Suppl):26S-29S. PubMed ID: 10803775
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Isotretinoin (13-cis-retinoic acid) metabolism, cis-trans isomerization, glucuronidation, and transfer to the mouse embryo: consequences for teratogenicity.
    Creech Kraft J; Eckhoff C; Kochhar DM; Bochert G; Chahoud I; Nau H
    Teratog Carcinog Mutagen; 1991; 11(1):21-30. PubMed ID: 1677495
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Steady state pharmacokinetics of oral treatment with 13-cis-retinoic acid or all-trans-retinoic acid in male and female adult rats.
    Ferguson SA; Siitonen PH; Cisneros FJ; Gough B; Young JF
    Basic Clin Pharmacol Toxicol; 2006 Jun; 98(6):582-7. PubMed ID: 16700821
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Teratogenicity of isotretinoin revisited: species variation and the role of all-trans-retinoic acid.
    Nau H
    J Am Acad Dermatol; 2001 Nov; 45(5):S183-7. PubMed ID: 11606951
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Developmental stage-associated differences in the transplacental distribution of 13-cis- and all-trans-retinoic acid as well as their glucuronides in rats and mice.
    Tzimas G; Collins MD; Nau H
    Toxicol Appl Pharmacol; 1995 Jul; 133(1):91-101. PubMed ID: 7597714
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.