These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
288 related articles for article (PubMed ID: 7627960)
1. Metabolic activation of N-hydroxyarylamines and N-hydroxyarylamides by 16 recombinant human NAT2 allozymes: effects of 7 specific NAT2 nucleic acid substitutions. Hein DW; Doll MA; Rustan TD; Ferguson RJ Cancer Res; 1995 Aug; 55(16):3531-6. PubMed ID: 7627960 [TBL] [Abstract][Full Text] [Related]
2. Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus. Hein DW; Doll MA; Gray K; Rustan TD; Ferguson RJ Cancer Res; 1993 Feb; 53(3):509-14. PubMed ID: 8425184 [TBL] [Abstract][Full Text] [Related]
3. Cloning, sequencing, and recombinant expression of NAT1, NAT2, and NAT3 derived from the C3H/HeJ (rapid) and A/HeJ (slow) acetylator inbred mouse: functional characterization of the activation and deactivation of aromatic amine carcinogens. Fretland AJ; Doll MA; Gray K; Feng Y; Hein DW Toxicol Appl Pharmacol; 1997 Feb; 142(2):360-6. PubMed ID: 9070359 [TBL] [Abstract][Full Text] [Related]
4. Molecular genetics of human polymorphic N-acetyltransferase: enzymatic analysis of 15 recombinant wild-type, mutant, and chimeric NAT2 allozymes. Hein DW; Ferguson RJ; Doll MA; Rustan TD; Gray K Hum Mol Genet; 1994 May; 3(5):729-34. PubMed ID: 8081359 [TBL] [Abstract][Full Text] [Related]
5. Purification of hepatic polymorphic arylamine N-acetyltransferase from homozygous rapid acetylator inbred hamster: identity with polymorphic N-hydroxyarylamine-O-acetyltransferase. Trinidad A; Hein DW; Rustan TD; Ferguson RJ; Miller LS; Bucher KD; Kirlin WG; Ogolla F; Andrews AF Cancer Res; 1990 Dec; 50(24):7942-9. PubMed ID: 2253236 [TBL] [Abstract][Full Text] [Related]
6. Cloning, expression, and functional characterization of two mutant (NAT2(191) and NAT2(341/803)) and wild-type human polymorphic N-acetyltransferase (NAT2) alleles. Ferguson RJ; Doll MA; Rustan TD; Gray K; Hein DW Drug Metab Dispos; 1994; 22(3):371-6. PubMed ID: 7915226 [TBL] [Abstract][Full Text] [Related]
7. Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): acetylator genotype-dependent N- and O-acetylation of arylamine carcinogens. Hein DW; Doll MA; Rustan TD; Gray K; Ferguson RJ; Feng Y Toxicol Appl Pharmacol; 1994 Jan; 124(1):16-24. PubMed ID: 8291057 [TBL] [Abstract][Full Text] [Related]
8. Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases. Hein DW; Doll MA; Rustan TD; Gray K; Feng Y; Ferguson RJ; Grant DM Carcinogenesis; 1993 Aug; 14(8):1633-8. PubMed ID: 8353847 [TBL] [Abstract][Full Text] [Related]
9. Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes. Grant DM; Blum M; Beer M; Meyer UA Mol Pharmacol; 1991 Feb; 39(2):184-91. PubMed ID: 1996083 [TBL] [Abstract][Full Text] [Related]
10. Catalytic properties and heat stabilities of novel recombinant human N-acetyltransferase 2 allozymes support existence of genetic heterogeneity within the slow acetylator phenotype. Hein DW; Doll MA Arch Toxicol; 2017 Aug; 91(8):2827-2835. PubMed ID: 28523442 [TBL] [Abstract][Full Text] [Related]
11. Polymorphic expression of acetyl coenzyme A-dependent arylamine N-acetyltransferase and acetyl coenzyme A-dependent O-acetyltransferase-mediated activation of N-hydroxyarylamines by human bladder cytosol. Kirlin WG; Trinidad A; Yerokun T; Ogolla F; Ferguson RJ; Andrews AF; Brady PK; Hein DW Cancer Res; 1989 May; 49(9):2448-54. PubMed ID: 2784998 [TBL] [Abstract][Full Text] [Related]
12. Effects of single nucleotide polymorphisms in human N-acetyltransferase 2 on metabolic activation (O-acetylation) of heterocyclic amine carcinogens. Hein DW; Fretland AJ; Doll MA Int J Cancer; 2006 Sep; 119(5):1208-11. PubMed ID: 16570281 [TBL] [Abstract][Full Text] [Related]
13. Recombinant expression and catalytic analysis of rapid and slow acetylator Syrian hamster chimeric NAT2 alleles. Hein DW; Ferguson RJ; Doll MA; Deitz AC Arch Toxicol; 1997; 71(5):306-13. PubMed ID: 9137809 [TBL] [Abstract][Full Text] [Related]
14. Metabolic activation of aromatic and heterocyclic N-hydroxyarylamines by wild-type and mutant recombinant human NAT1 and NAT2 acetyltransferases. Hein DW; Rustan TD; Ferguson RJ; Doll MA; Gray K Arch Toxicol; 1994; 68(2):129-33. PubMed ID: 8179482 [TBL] [Abstract][Full Text] [Related]
15. Role of N-acetyltransferase 2 acetylation polymorphism in 4, 4'-methylene bis (2-chloroaniline) biotransformation. Hein DW; Zhang X; Doll MA Toxicol Lett; 2018 Feb; 283():100-105. PubMed ID: 29180287 [TBL] [Abstract][Full Text] [Related]
16. Isoform-selective inactivation of human arylamine N-acetyltransferases by reactive metabolites of carcinogenic arylamines. Liu L; Wagner CR; Hanna PE Chem Res Toxicol; 2009 Dec; 22(12):1962-74. PubMed ID: 19842618 [TBL] [Abstract][Full Text] [Related]
17. Cloning, expression, and functional characterization of rapid and slow acetylator polymorphic N-acetyl-transferase encoding genes of the Syrian hamster. Ferguson RJ; Doll MA; Rustan TD; Hein DW Pharmacogenetics; 1996 Feb; 6(1):55-66. PubMed ID: 8845861 [TBL] [Abstract][Full Text] [Related]
18. Acetylator genotype-dependent metabolic activation of carcinogenic N-hydroxyarylamines by S-acetyl coenzyme A-dependent enzymes of inbred hamster tissue cytosols: relationship to arylamine N-acetyltransferase. Hein DW; Flammang TJ; Kirlin WG; Trinidad A; Ogolla F Carcinogenesis; 1987 Dec; 8(12):1767-74. PubMed ID: 3677303 [TBL] [Abstract][Full Text] [Related]
19. Acetylator genotype-dependent expression of arylamine N-acetyltransferase and N-hydroxyarylamine O-acetyltransferase in Syrian inbred hamster intestine and colon. Identity with the hepatic acetylation polymorphism. Ogolla F; Ferguson RJ; Kirlin WG; Trinidad A; Andrews AF; Mpezo M; Hein DW Drug Metab Dispos; 1990; 18(5):680-5. PubMed ID: 1981720 [TBL] [Abstract][Full Text] [Related]
20. 4-Aminobiphenyl downregulation of NAT2 acetylator genotype-dependent N- and O-acetylation of aromatic and heterocyclic amine carcinogens in primary mammary epithelial cell cultures from rapid and slow acetylator rats. Jefferson FA; Xiao GH; Hein DW Toxicol Sci; 2009 Jan; 107(1):293-7. PubMed ID: 18842621 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]