BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

193 related articles for article (PubMed ID: 7636877)

  • 1. Design and synthesis of potent retinoid X receptor selective ligands that induce apoptosis in leukemia cells.
    Boehm MF; Zhang L; Zhi L; McClurg MR; Berger E; Wagoner M; Mais DE; Suto CM; Davies JA; Heyman RA
    J Med Chem; 1995 Aug; 38(16):3146-55. PubMed ID: 7636877
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of novel retinoid X receptor-selective ligands on myeloid leukemia differentiation and proliferation in vitro.
    Kizaki M; Dawson MI; Heyman R; Elster E; Morosetti R; Pakkala S; Chen DL; Ueno H; Chao W; Morikawa M; Ikeda Y; Heber D; Pfahl M; Koeffler HP
    Blood; 1996 Mar; 87(5):1977-84. PubMed ID: 8634447
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and structure-activity relationships of novel retinoid X receptor-selective retinoids.
    Boehm MF; Zhang L; Badea BA; White SK; Mais DE; Berger E; Suto CM; Goldman ME; Heyman RA
    J Med Chem; 1994 Sep; 37(18):2930-41. PubMed ID: 8071941
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Effects of retinoid treatment of rats on hepatic microsomal metabolism and cytochromes P450. Correlation between retinoic acid receptor/retinoid x receptor selectivity and effects on metabolic enzymes.
    Howell SR; Shirley MA; Ulm EH
    Drug Metab Dispos; 1998 Mar; 26(3):234-9. PubMed ID: 9492386
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Synthesis and structure-activity relationships of stilbene retinoid analogs substituted with heteroaromatic carboxylic acids.
    Beard RL; Chandraratna RA; Colon DF; Gillett SJ; Henry E; Marler DK; Song T; Denys L; Garst ME; Arefieg T
    J Med Chem; 1995 Jul; 38(15):2820-9. PubMed ID: 7636843
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Modeling, Synthesis, and Biological Evaluation of Potential Retinoid X Receptor (RXR)-Selective Agonists: Analogues of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(5,5,8,8-tetrahydronaphthalen-2-yl)amino)nicotinic Acid (NEt-TMN).
    Heck MC; Wagner CE; Shahani PH; MacNeill M; Grozic A; Darwaiz T; Shimabuku M; Deans DG; Robinson NM; Salama SH; Ziller JW; Ma N; van der Vaart A; Marshall PA; Jurutka PW
    J Med Chem; 2016 Oct; 59(19):8924-8940. PubMed ID: 27592633
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Retinoid X receptor agonist elevation of serum triglycerides in rats by potentiation of retinoic acid receptor agonist induction or by action as single agents.
    Standeven AM; Thacher SM; Yuan YD; Escobar M; Vuligonda V; Beard RL; Chandraratna RA
    Biochem Pharmacol; 2001 Dec; 62(11):1501-9. PubMed ID: 11728386
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Evidence for the involvement of retinoic acid receptor RAR alpha-dependent signaling pathway in the induction of tissue transglutaminase and apoptosis by retinoids.
    Zhang LX; Mills KJ; Dawson MI; Collins SJ; Jetten AM
    J Biol Chem; 1995 Mar; 270(11):6022-9. PubMed ID: 7890733
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ligand-bound RXR can mediate retinoid signal transduction during embryogenesis.
    Lu HC; Eichele G; Thaller C
    Development; 1997 Jan; 124(1):195-203. PubMed ID: 9006080
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Retinoic acid receptor- and retinoid X receptor-selective retinoids activate signaling pathways that converge on AP-1 and inhibit squamous differentiation in human bronchial epithelial cells.
    Lee HY; Dawson MI; Walsh GL; Nesbitt JC; Eckert RL; Fuchs E; Hong WK; Lotan R; Kurie JM
    Cell Growth Differ; 1996 Aug; 7(8):997-1004. PubMed ID: 8853895
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Retinoic acid receptor alpha expression correlates with retinoid-induced growth inhibition of human breast cancer cells regardless of estrogen receptor status.
    Fitzgerald P; Teng M; Chandraratna RA; Heyman RA; Allegretto EA
    Cancer Res; 1997 Jul; 57(13):2642-50. PubMed ID: 9205071
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of apolipoprotein(a) synthesis in cynomolgus monkey hepatocytes by retinoids via involvement of the retinoic acid receptor.
    Neele DM; de Wit EC; Princen HM
    Biochem Pharmacol; 1999 Jul; 58(2):263-71. PubMed ID: 10423167
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Modeling, synthesis, and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene) and (E)-3-(3-(1,2,3,4-tetrahydro-1,1,4,4,6-pentamethylnaphthalen-7-yl)-4-hydroxyphenyl)acrylic acid (CD3254).
    Jurutka PW; Kaneko I; Yang J; Bhogal JS; Swierski JC; Tabacaru CR; Montano LA; Huynh CC; Jama RA; Mahelona RD; Sarnowski JT; Marcus LM; Quezada A; Lemming B; Tedesco MA; Fischer AJ; Mohamed SA; Ziller JW; Ma N; Gray GM; van der Vaart A; Marshall PA; Wagner CE
    J Med Chem; 2013 Nov; 56(21):8432-54. PubMed ID: 24180745
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modeling, synthesis and biological evaluation of potential retinoid X receptor (RXR) selective agonists: novel analogues of 4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethynyl]benzoic acid (bexarotene).
    Wagner CE; Jurutka PW; Marshall PA; Groy TL; van der Vaart A; Ziller JW; Furmick JK; Graeber ME; Matro E; Miguel BV; Tran IT; Kwon J; Tedeschi JN; Moosavi S; Danishyar A; Philp JS; Khamees RO; Jackson JN; Grupe DK; Badshah SL; Hart JW
    J Med Chem; 2009 Oct; 52(19):5950-66. PubMed ID: 19791803
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Evidence for the involvement of both retinoic acid receptor- and retinoic X receptor-dependent signaling pathways in the induction of tissue transglutaminase and apoptosis in the human myeloma cell line RPMI 8226.
    Joseph B; Lefebvre O; Méreau-Richard C; Danzé PM; Belin-Plancot MT; Formstecher P
    Blood; 1998 Apr; 91(7):2423-32. PubMed ID: 9516142
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Suppression of human pancreatic cancer cell proliferation by AGN194204, an RXR-selective retinoid.
    Balasubramanian S; Chandraratna RA; Eckert RL
    Carcinogenesis; 2004 Aug; 25(8):1377-85. PubMed ID: 14976133
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Modeling, Synthesis, and Biological Evaluation of Potential Retinoid-X-Receptor (RXR) Selective Agonists: Analogs of 4-[1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahyro-2-naphthyl)ethynyl]benzoic Acid (Bexarotene) and 6-(Ethyl(4-isobutoxy-3-isopropylphenyl)amino)nicotinic Acid (NEt-4IB).
    Jurutka PW; di Martino O; Reshi S; Mallick S; Sabir ZL; Staniszewski LJP; Warda A; Maiorella EL; Minasian A; Davidson J; Ibrahim SJ; Raban S; Haddad D; Khamisi M; Suban SL; Dawson BJ; Candia R; Ziller JW; Lee MY; Liu C; Liu W; Marshall PA; Welch JS; Wagner CE
    Int J Mol Sci; 2021 Nov; 22(22):. PubMed ID: 34830251
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of specific RXR heterodimers by an antagonist of RXR homodimers.
    Lala DS; Mukherjee R; Schulman IG; Koch SS; Dardashti LJ; Nadzan AM; Croston GE; Evans RM; Heyman RA
    Nature; 1996 Oct; 383(6599):450-3. PubMed ID: 8837780
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stereoselective synthesis and receptor activity of conformationally defined retinoid X receptor selective ligands.
    Vuligonda V; Garst ME; Chandraratna RA
    Bioorg Med Chem Lett; 1999 Feb; 9(4):589-94. PubMed ID: 10098670
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis, structure-activity relationships, and RARgamma-ligand interactions of nitrogen heteroarotinoids.
    Dhar A; Liu S; Klucik J; Berlin KD; Madler MM; Lu S; Ivey RT; Zacheis D; Brown CW; Nelson EC; Birckbichler PJ; Benbrook DM
    J Med Chem; 1999 Sep; 42(18):3602-14. PubMed ID: 10479291
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.