BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

790 related articles for article (PubMed ID: 7637810)

  • 1. Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction.
    Burgering BM; Coffer PJ
    Nature; 1995 Aug; 376(6541):599-602. PubMed ID: 7637810
    [TBL] [Abstract][Full Text] [Related]  

  • 2. PDGF- and insulin-dependent pp70S6k activation mediated by phosphatidylinositol-3-OH kinase.
    Chung J; Grammer TC; Lemon KP; Kazlauskas A; Blenis J
    Nature; 1994 Jul; 370(6484):71-5. PubMed ID: 8015612
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Matrix adhesion and Ras transformation both activate a phosphoinositide 3-OH kinase and protein kinase B/Akt cellular survival pathway.
    Khwaja A; Rodriguez-Viciana P; Wennström S; Warne PH; Downward J
    EMBO J; 1997 May; 16(10):2783-93. PubMed ID: 9184223
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The cell survival signal Akt is differentially activated by PDGF-BB, EGF, and FGF-2 in osteoblastic cells.
    Chaudhary LR; Hruska KA
    J Cell Biochem; 2001 Mar; 81(2):304-11. PubMed ID: 11241670
    [TBL] [Abstract][Full Text] [Related]  

  • 5. p21ras initiates Rac-1 but not phosphatidyl inositol 3 kinase/PKB, mediated signaling pathways in T lymphocytes.
    Genot E; Reif K; Beach S; Kramer I; Cantrell D
    Oncogene; 1998 Oct; 17(13):1731-8. PubMed ID: 9796702
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A direct linkage between the phosphoinositide 3-kinase-AKT signaling pathway and the mammalian target of rapamycin in mitogen-stimulated and transformed cells.
    Sekulić A; Hudson CC; Homme JL; Yin P; Otterness DM; Karnitz LM; Abraham RT
    Cancer Res; 2000 Jul; 60(13):3504-13. PubMed ID: 10910062
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Mammalian target of rapamycin is a direct target for protein kinase B: identification of a convergence point for opposing effects of insulin and amino-acid deficiency on protein translation.
    Navé BT; Ouwens M; Withers DJ; Alessi DR; Shepherd PR
    Biochem J; 1999 Dec; 344 Pt 2(Pt 2):427-31. PubMed ID: 10567225
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.
    Kauffmann-Zeh A; Rodriguez-Viciana P; Ulrich E; Gilbert C; Coffer P; Downward J; Evan G
    Nature; 1997 Feb; 385(6616):544-8. PubMed ID: 9020362
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Phosphatidylinositol 3-kinase, protein kinase B and ribosomal S6 kinases in the stimulation of thyroid epithelial cell proliferation by cAMP and growth factors in the presence of insulin.
    Coulonval K; Vandeput F; Stein RC; Kozma SC; Lamy F; Dumont JE
    Biochem J; 2000 Jun; 348 Pt 2(Pt 2):351-8. PubMed ID: 10816429
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Protein kinase B activation and lamellipodium formation are independent phosphoinositide 3-kinase-mediated events differentially regulated by endogenous Ras.
    van Weering DH; de Rooij J; Marte B; Downward J; Bos JL; Burgering BM
    Mol Cell Biol; 1998 Apr; 18(4):1802-11. PubMed ID: 9528752
    [TBL] [Abstract][Full Text] [Related]  

  • 11. AKT2, a member of the protein kinase B family, is activated by growth factors, v-Ha-ras, and v-src through phosphatidylinositol 3-kinase in human ovarian epithelial cancer cells.
    Liu AX; Testa JR; Hamilton TC; Jove R; Nicosia SV; Cheng JQ
    Cancer Res; 1998 Jul; 58(14):2973-7. PubMed ID: 9679957
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Insulin, insulin-like growth factor-I, and platelet-derived growth factor activate extracellular signal-regulated kinase by distinct pathways in muscle cells.
    Tsakiridis T; Tsiani E; Lekas P; Bergman A; Cherepanov V; Whiteside C; Downey GP
    Biochem Biophys Res Commun; 2001 Oct; 288(1):205-11. PubMed ID: 11594774
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Hypoxia activates a platelet-derived growth factor receptor/phosphatidylinositol 3-kinase/Akt pathway that results in glycogen synthase kinase-3 inactivation.
    Chen EY; Mazure NM; Cooper JA; Giaccia AJ
    Cancer Res; 2001 Mar; 61(6):2429-33. PubMed ID: 11289110
    [TBL] [Abstract][Full Text] [Related]  

  • 14. IL2-dependent phosphorylation of 40S ribosomal protein S6 is controlled by PI-3K/mTOR signalling in CTLL2 cells.
    Tuhácková Z; Sloncová E; Vojtechová M; Sovová V
    Int J Mol Med; 2004 Apr; 13(4):601-5. PubMed ID: 15010863
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The regulation and activities of the multifunctional serine/threonine kinase Akt/PKB.
    Kandel ES; Hay N
    Exp Cell Res; 1999 Nov; 253(1):210-29. PubMed ID: 10579924
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Signal transduction. Regulating S6 kinase.
    Downward J
    Nature; 1994 Sep; 371(6496):378-9. PubMed ID: 8090217
    [No Abstract]   [Full Text] [Related]  

  • 17. Constitutive activation of protein kinase B and phosphorylation of p47phox by a membrane-targeted phosphoinositide 3-kinase.
    Didichenko SA; Tilton B; Hemmings BA; Ballmer-Hofer K; Thelen M
    Curr Biol; 1996 Oct; 6(10):1271-8. PubMed ID: 8939574
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Requirement of the serine-threonine kinase Akt for heat treatment-induced activation of p70 S6 kinase.
    Kuroda S; Ogawa W; Kitamura T; Konishi H; Kikkawa U; Kasuga M
    Biochem Biophys Res Commun; 1998 Aug; 249(3):781-5. PubMed ID: 9731213
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase.
    Franke TF; Yang SI; Chan TO; Datta K; Kazlauskas A; Morrison DK; Kaplan DR; Tsichlis PN
    Cell; 1995 Jun; 81(5):727-36. PubMed ID: 7774014
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway.
    Scott PH; Brunn GJ; Kohn AD; Roth RA; Lawrence JC
    Proc Natl Acad Sci U S A; 1998 Jun; 95(13):7772-7. PubMed ID: 9636226
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 40.