BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

273 related articles for article (PubMed ID: 7639929)

  • 1. Design, synthesis, DNA sequence preferential alkylation and biological evaluation of N-mustard derivatives of distamycin and netropsin analogues.
    Xie G; Gupta R; Lown JW
    Anticancer Drug Des; 1995 Jul; 10(5):389-409. PubMed ID: 7639929
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Design, synthesis, DNA sequence preferential alkylation and biological evaluation of N-mustard derivatives of Hoechst 33258 analogues.
    Gupta R; Wang H; Huang L; Lown JW
    Anticancer Drug Des; 1995 Jan; 10(1):25-41. PubMed ID: 7535056
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Novel DNA-directed alkylating agents consisting of naphthalimide, nitrogen mustard and lexitropsin moieties: synthesis, DNA sequence specificity and biological evaluation.
    Gupta R; Liu J; Xie G; Lown JW
    Anticancer Drug Des; 1996 Dec; 11(8):581-96. PubMed ID: 9022747
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis, DNA binding, cytotoxicity and sequence specificity of a series of imidazole-containing analogs of the benzoic acid mustard distamycin derivative tallimustine containing an alkylating group at the C-terminus.
    Brooks N; Lee M; Wright SR; Woo S; Centioni S; Hartley JA
    Anticancer Drug Des; 1997 Oct; 12(7):591-606. PubMed ID: 9365504
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis and biological evaluation of benzoic acid mustard derivatives of imidazole-containing and C-terminal carboxamide analogues of distamycin.
    Hartley JA; Preti CS; Wyatt MD; Lee M
    Drug Des Discov; 1995 Apr; 12(4):323-35. PubMed ID: 9040992
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA-Directed alkylating agents. 7. Synthesis, DNA interaction, and antitumor activity of bis(hydroxymethyl)- and bis(carbamate)-substituted pyrrolizines and imidazoles.
    Atwell GJ; Fan JY; Tan K; Denny WA
    J Med Chem; 1998 Nov; 41(24):4744-54. PubMed ID: 9822545
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Selective DNA interaction of the novel distamycin derivative FCE 24517.
    Broggini M; Erba E; Ponti M; Ballinari D; Geroni C; Spreafico F; D'Incalci M
    Cancer Res; 1991 Jan; 51(1):199-204. PubMed ID: 1859575
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Backbone and benzoyl mustard carrying moiety modifies DNA interactions of distamycin analogues.
    Ciucci A; Manzini S; Lombardi P; Arcamone F
    Nucleic Acids Res; 1996 Jan; 24(2):311-5. PubMed ID: 8628655
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Sequence selectivity, cross-linking efficiency and cytotoxicity of DNA-targeted 4-anilinoquinoline aniline mustards.
    McClean S; Costelloe C; Denny WA; Searcey M; Wakelin LP
    Anticancer Drug Des; 1999 Jun; 14(3):187-204. PubMed ID: 10500495
    [TBL] [Abstract][Full Text] [Related]  

  • 10. N-(2-chloroethyl)-N-nitrosourea tethered to lexitropsin induces minor groove lesions at the p53 cDNA that are more cytotoxic than mutagenic.
    Inga A; Chen FX; Monti P; Aprile A; Campomenosi P; Menichini P; Ottaggio L; Viaggi S; Abbondandolo A; Gold B; Fronza G
    Cancer Res; 1999 Feb; 59(3):689-95. PubMed ID: 9973219
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA minor groove targeted alkylating agents based on bisbenzimidazole carriers: synthesis, cytotoxicity and sequence-specificity of DNA alkylation.
    Smaill JB; Fan JY; Denny WA
    Anticancer Drug Des; 1998 Dec; 13(8):857-80. PubMed ID: 10335264
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthetic analogues of netropsin and distamycin. I. Pyridine-containing analogues of distamycin--a molecular modelling study.
    Bielawski K; Bartulewicz D; Rózański A
    Rocz Akad Med Bialymst; 1995; 40(2):352-63. PubMed ID: 8834619
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Combinatorial identification of a novel consensus sequence for the covalent DNA-binding polyamide tallimustine.
    Sunavala-Dossabhoy G; Van Dyke MW
    Biochemistry; 2005 Feb; 44(7):2510-22. PubMed ID: 15709763
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthetic analogues of netropsin and distamycin. III. Synthesis of a pyridine analogue of the pyrrolecarboxamide antitumour antibiotics.
    Bielawski K; Bartulewicz D; Krajewska D; Rózański A
    Rocz Akad Med Bialymst; 1996; 41(2):293-304. PubMed ID: 9020541
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Carbocyclic analogues of netropsin and distamycin: DNA-binding properties and inhibition of DNA topoisomerases.
    Bartulewicz D; Bielawski K; Bielawska A
    Arch Pharm (Weinheim); 2002 Nov; 335(9):422-6. PubMed ID: 12447915
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-activity relationship of a series of nitrogen mustard- and pyrrole-containing minor groove-binding agents related to distamycin.
    Wyatt MD; Garbiras BJ; Haskell MK; Lee M; Souhami RL; Hartley JA
    Anticancer Drug Des; 1994 Dec; 9(6):511-25. PubMed ID: 7880376
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The effect of AT and GC sequence specific minor groove-binding agents on restriction endonuclease activity.
    Forrow SM; Lee M; Souhami RL; Hartley JA
    Chem Biol Interact; 1995 May; 96(2):125-42. PubMed ID: 7728903
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Ligands possessing affinity to specific DNA base pair sequences. IX. Synthesis of netropsin and distamycin A analogs having sarcolysin residues or a platinum(II) atom].
    Grokhovskiĭ SL; Gottikh BP; Zhuze AL
    Bioorg Khim; 1992 Apr; 18(4):570-83. PubMed ID: 1323966
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Design, synthesis, and biological evaluation of DNA sequence and minor groove selective alkylating agents.
    Lee M; Rhodes AL; Wyatt MD; Forrow S; Hartley JA
    Anticancer Drug Des; 1993 Jun; 8(3):173-92. PubMed ID: 8517912
    [TBL] [Abstract][Full Text] [Related]  

  • 20. DNA binding properties of FCE24517, an electrophilic distamycin analogue.
    Fontana M; Lestingi M; Mondello C; Braghetti A; Montecucco A; Ciarrocchi G
    Anticancer Drug Des; 1992 Apr; 7(2):131-41. PubMed ID: 1575886
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.