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2. The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1. Rozakis-Adcock M; Fernley R; Wade J; Pawson T; Bowtell D Nature; 1993 May; 363(6424):83-5. PubMed ID: 8479540 [TBL] [Abstract][Full Text] [Related]
3. Independent binding of peptide ligands to the SH2 and SH3 domains of Grb2. Lemmon MA; Ladbury JE; Mandiyan V; Zhou M; Schlessinger J J Biol Chem; 1994 Dec; 269(50):31653-8. PubMed ID: 7527391 [TBL] [Abstract][Full Text] [Related]
4. SH3 domains of the adapter molecule Grb2 complex with two proteins in T cells: the guanine nucleotide exchange protein Sos and a 75-kDa protein that is a substrate for T cell antigen receptor-activated tyrosine kinases. Reif K; Buday L; Downward J; Cantrell DA J Biol Chem; 1994 May; 269(19):14081-7. PubMed ID: 8188688 [TBL] [Abstract][Full Text] [Related]
5. Sos, Vav, and C3G participate in B cell receptor-induced signaling pathways and differentially associate with Shc-Grb2, Crk, and Crk-L adaptors. Smit L; van der Horst G; Borst J J Biol Chem; 1996 Apr; 271(15):8564-9. PubMed ID: 8621483 [TBL] [Abstract][Full Text] [Related]
6. Tight association of GRB2 with receptor protein-tyrosine phosphatase alpha is mediated by the SH2 and C-terminal SH3 domains. den Hertog J; Hunter T EMBO J; 1996 Jun; 15(12):3016-27. PubMed ID: 8670803 [TBL] [Abstract][Full Text] [Related]
7. Binding of the Grb2 SH2 domain to phosphotyrosine motifs does not change the affinity of its SH3 domains for Sos proline-rich motifs. Cussac D; Frech M; Chardin P EMBO J; 1994 Sep; 13(17):4011-21. PubMed ID: 7521298 [TBL] [Abstract][Full Text] [Related]
9. Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation. Egan SE; Giddings BW; Brooks MW; Buday L; Sizeland AM; Weinberg RA Nature; 1993 May; 363(6424):45-51. PubMed ID: 8479536 [TBL] [Abstract][Full Text] [Related]
10. Shc contains two Grb2 binding sites needed for efficient formation of complexes with SOS in B lymphocytes. Harmer SL; DeFranco AL Mol Cell Biol; 1997 Jul; 17(7):4087-95. PubMed ID: 9199344 [TBL] [Abstract][Full Text] [Related]
11. Dok-3 sequesters Grb2 and inhibits the Ras-Erk pathway downstream of protein-tyrosine kinases. Honma M; Higuchi O; Shirakata M; Yasuda T; Shibuya H; Iemura S; Natsume T; Yamanashi Y Genes Cells; 2006 Feb; 11(2):143-51. PubMed ID: 16436051 [TBL] [Abstract][Full Text] [Related]
12. Grb2 SH3 binding to peptides from Sos: evaluation of a general model for SH3-ligand interactions. Simon JA; Schreiber SL Chem Biol; 1995 Jan; 2(1):53-60. PubMed ID: 9383403 [TBL] [Abstract][Full Text] [Related]
13. Identification of Grb2 as a novel binding partner of tumor necrosis factor (TNF) receptor I. Hildt E; Oess S J Exp Med; 1999 Jun; 189(11):1707-14. PubMed ID: 10359574 [TBL] [Abstract][Full Text] [Related]
14. Association of Shc, Cbl, Grb2, and Sos following treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin in primary rat hepatocytes. Park R; Kim DH; Kim MS; So HS; Chung HT; Kwon KB; Ryu DG; Kim BR Biochem Biophys Res Commun; 1998 Dec; 253(3):577-81. PubMed ID: 9918770 [TBL] [Abstract][Full Text] [Related]
15. Inhibitors of Ras signal transduction as antitumor agents. Garbay C; Liu WQ; Vidal M; Roques BP Biochem Pharmacol; 2000 Oct; 60(8):1165-9. PubMed ID: 11007954 [TBL] [Abstract][Full Text] [Related]
16. A Drosophila SH2-SH3 adaptor protein implicated in coupling the sevenless tyrosine kinase to an activator of Ras guanine nucleotide exchange, Sos. Olivier JP; Raabe T; Henkemeyer M; Dickson B; Mbamalu G; Margolis B; Schlessinger J; Hafen E; Pawson T Cell; 1993 Apr; 73(1):179-91. PubMed ID: 8462098 [TBL] [Abstract][Full Text] [Related]
17. A complex of Grb2 adaptor protein, Sos exchange factor, and a 36-kDa membrane-bound tyrosine phosphoprotein is implicated in ras activation in T cells. Buday L; Egan SE; Rodriguez Viciana P; Cantrell DA; Downward J J Biol Chem; 1994 Mar; 269(12):9019-23. PubMed ID: 7510700 [TBL] [Abstract][Full Text] [Related]
18. Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor. Nioche P; Liu WQ; Broutin I; Charbonnier F; Latreille MT; Vidal M; Roques B; Garbay C; Ducruix A J Mol Biol; 2002 Feb; 315(5):1167-77. PubMed ID: 11827484 [TBL] [Abstract][Full Text] [Related]