These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

244 related articles for article (PubMed ID: 7647777)

  • 21. Caspase cleavage of mutant huntingtin precedes neurodegeneration in Huntington's disease.
    Wellington CL; Ellerby LM; Gutekunst CA; Rogers D; Warby S; Graham RK; Loubser O; van Raamsdonk J; Singaraja R; Yang YZ; Gafni J; Bredesen D; Hersch SM; Leavitt BR; Roy S; Nicholson DW; Hayden MR
    J Neurosci; 2002 Sep; 22(18):7862-72. PubMed ID: 12223539
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Huntingtin's WW domain partners in Huntington's disease post-mortem brain fulfill genetic criteria for direct involvement in Huntington's disease pathogenesis.
    Passani LA; Bedford MT; Faber PW; McGinnis KM; Sharp AH; Gusella JF; Vonsattel JP; MacDonald ME
    Hum Mol Genet; 2000 Sep; 9(14):2175-82. PubMed ID: 10958656
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length.
    de Almeida LP; Ross CA; Zala D; Aebischer P; Déglon N
    J Neurosci; 2002 May; 22(9):3473-83. PubMed ID: 11978824
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Essential sequence of the N-terminal cytoplasmic localization-related domain of huntingtin and its effect on huntingtin aggregates.
    Yan Y; Peng D; Tian J; Chi J; Tan J; Yin X; Pu J; Xia K; Zhang B
    Sci China Life Sci; 2011 Apr; 54(4):342-50. PubMed ID: 21509658
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Polyglutamine expansion as a pathological epitope in Huntington's disease and four dominant cerebellar ataxias.
    Trottier Y; Lutz Y; Stevanin G; Imbert G; Devys D; Cancel G; Saudou F; Weber C; David G; Tora L
    Nature; 1995 Nov; 378(6555):403-6. PubMed ID: 7477379
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Expression of the Huntington disease gene in rodents: cloning the rat homologue and evidence for downregulation in non-neuronal tissues during development.
    Schmitt I; Bächner D; Megow D; Henklein P; Hameister H; Epplen JT; Riess O
    Hum Mol Genet; 1995 Jul; 4(7):1173-82. PubMed ID: 8528205
    [TBL] [Abstract][Full Text] [Related]  

  • 27. PACSIN 1 interacts with huntingtin and is absent from synaptic varicosities in presymptomatic Huntington's disease brains.
    Modregger J; DiProspero NA; Charles V; Tagle DA; Plomann M
    Hum Mol Genet; 2002 Oct; 11(21):2547-58. PubMed ID: 12354780
    [TBL] [Abstract][Full Text] [Related]  

  • 28. A human HAP1 homologue. Cloning, expression, and interaction with huntingtin.
    Li SH; Hosseini SH; Gutekunst CA; Hersch SM; Ferrante RJ; Li XJ
    J Biol Chem; 1998 Jul; 273(30):19220-7. PubMed ID: 9668110
    [TBL] [Abstract][Full Text] [Related]  

  • 29. How does the Huntington's disease mutation damage cells?
    Rubinsztein DC
    Sci Aging Knowledge Environ; 2003 Sep; 2003(37):PE26. PubMed ID: 13679594
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Rapid aggregate formation of the huntingtin N-terminal fragment carrying an expanded polyglutamine tract.
    Hazeki N; Nakamura K; Goto J; Kanazawa I
    Biochem Biophys Res Commun; 1999 Mar; 256(2):361-6. PubMed ID: 10079189
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Unraveling a role for dopamine in Huntington's disease: the dual role of reactive oxygen species and D2 receptor stimulation.
    Charvin D; Vanhoutte P; Pagès C; Borrelli E; Caboche J
    Proc Natl Acad Sci U S A; 2005 Aug; 102(34):12218-23. PubMed ID: 16103364
    [TBL] [Abstract][Full Text] [Related]  

  • 32. In vitro evidence for both the nucleus and cytoplasm as subcellular sites of pathogenesis in Huntington's disease.
    Hackam AS; Singaraja R; Zhang T; Gan L; Hayden MR
    Hum Mol Genet; 1999 Jan; 8(1):25-33. PubMed ID: 9887328
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Expression of normal and mutant huntingtin in the developing brain.
    Bhide PG; Day M; Sapp E; Schwarz C; Sheth A; Kim J; Young AB; Penney J; Golden J; Aronin N; DiFiglia M
    J Neurosci; 1996 Sep; 16(17):5523-35. PubMed ID: 8757264
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Characterization and localization of the Huntington disease gene product.
    Hoogeveen AT; Willemsen R; Meyer N; de Rooij KE; Roos RA; van Ommen GJ; Galjaard H
    Hum Mol Genet; 1993 Dec; 2(12):2069-73. PubMed ID: 8111375
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Aggregation of N-terminal huntingtin is dependent on the length of its glutamine repeats.
    Li SH; Li XJ
    Hum Mol Genet; 1998 May; 7(5):777-82. PubMed ID: 9536080
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Neuronal distribution of intranuclear inclusions in Huntington's disease with adult onset.
    Gourfinkel-An I; Cancel G; Duyckaerts C; Faucheux B; Hauw JJ; Trottier Y; Brice A; Agid Y; Hirsch EC
    Neuroreport; 1998 Jun; 9(8):1823-6. PubMed ID: 9665608
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A cellular model that recapitulates major pathogenic steps of Huntington's disease.
    Lunkes A; Mandel JL
    Hum Mol Genet; 1998 Sep; 7(9):1355-61. PubMed ID: 9700187
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Normal and expanded Huntington's disease gene alleles produce distinguishable proteins due to translation across the CAG repeat.
    Persichetti F; Ambrose CM; Ge P; McNeil SM; Srinidhi J; Anderson MA; Jenkins B; Barnes GT; Duyao MP; Kanaley L
    Mol Med; 1995 May; 1(4):374-83. PubMed ID: 8521295
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Isolation of a 40-kDa Huntingtin-associated protein.
    Peters MF; Ross CA
    J Biol Chem; 2001 Feb; 276(5):3188-94. PubMed ID: 11035034
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Huntingtin is required for neurogenesis and is not impaired by the Huntington's disease CAG expansion.
    White JK; Auerbach W; Duyao MP; Vonsattel JP; Gusella JF; Joyner AL; MacDonald ME
    Nat Genet; 1997 Dec; 17(4):404-10. PubMed ID: 9398841
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 13.