155 related articles for article (PubMed ID: 7650689)
1. The role of water molecules in the structure-based design of (5-hydroxynorvaline)-2-cyclosporin: synthesis, biological activity, and crystallographic analysis with cyclophilin A.
Mikol V; Papageorgiou C; Borer X
J Med Chem; 1995 Aug; 38(17):3361-7. PubMed ID: 7650689
[TBL] [Abstract][Full Text] [Related]
2. The molecular replacement solution and X-ray refinement to 2.8 A of a decameric complex of human cyclophilin A with the immunosuppressive drug cyclosporin A.
Pflügl GM; Kallen J; Jansonius JN; Walkinshaw MD
J Mol Biol; 1994 Dec; 244(4):385-409. PubMed ID: 7990129
[TBL] [Abstract][Full Text] [Related]
3. X-ray structure of a cyclophilin B/cyclosporin complex: comparison with cyclophilin A and delineation of its calcineurin-binding domain.
Mikol V; Kallen J; Walkinshaw MD
Proc Natl Acad Sci U S A; 1994 May; 91(11):5183-6. PubMed ID: 8197205
[TBL] [Abstract][Full Text] [Related]
4. Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A.
Ke H; Mayrose D; Belshaw PJ; Alberg DG; Schreiber SL; Chang ZY; Etzkorn FA; Ho S; Walsh CT
Structure; 1994 Jan; 2(1):33-44. PubMed ID: 8075981
[TBL] [Abstract][Full Text] [Related]
5. Conformational polymorphism of cyclosporin A.
Altschuh D; Braun W; Kallen J; Mikol V; Spitzfaden C; Thierry JC; Vix O; Walkinshaw MD; Wüthrich K
Structure; 1994 Oct; 2(10):963-72. PubMed ID: 7866747
[TBL] [Abstract][Full Text] [Related]
6. Cyclosporin A-cyclophilin complex formation. A model based on X-ray and NMR data.
Spitzfaden C; Weber HP; Braun W; Kallen J; Wider G; Widmer H; Walkinshaw MD; Wüthrich K
FEBS Lett; 1992 Apr; 300(3):291-300. PubMed ID: 1555658
[TBL] [Abstract][Full Text] [Related]
7. Modeling conformational changes in cyclosporin A.
O'Donohue MF; Burgess AW; Walkinshaw MD; Treutlein HR
Protein Sci; 1995 Oct; 4(10):2191-202. PubMed ID: 8535256
[TBL] [Abstract][Full Text] [Related]
8. X-ray structure of a monomeric cyclophilin A-cyclosporin A crystal complex at 2.1 A resolution.
Mikol V; Kallen J; Pflügl G; Walkinshaw MD
J Mol Biol; 1993 Dec; 234(4):1119-30. PubMed ID: 8263916
[TBL] [Abstract][Full Text] [Related]
9. Solution structure of the cyclosporin A/cyclophilin complex by NMR.
Thériault Y; Logan TM; Meadows R; Yu L; Olejniczak ET; Holzman TF; Simmer RL; Fesik SW
Nature; 1993 Jan; 361(6407):88-91. PubMed ID: 8421500
[TBL] [Abstract][Full Text] [Related]
10. A conformation of cyclosporin A in aqueous environment revealed by the X-ray structure of a cyclosporin-Fab complex.
Altschuh D; Vix O; Rees B; Thierry JC
Science; 1992 Apr; 256(5053):92-4. PubMed ID: 1566062
[TBL] [Abstract][Full Text] [Related]
11. X-ray structure of a decameric cyclophilin-cyclosporin crystal complex.
Pflügl G; Kallen J; Schirmer T; Jansonius JN; Zurini MG; Walkinshaw MD
Nature; 1993 Jan; 361(6407):91-4. PubMed ID: 8421501
[TBL] [Abstract][Full Text] [Related]
12. NMR studies of [U-13C]cyclosporin A bound to human cyclophilin B.
Neri P; Gemmecker G; Zydowsky LD; Walsh CT; Fesik SW
FEBS Lett; 1991 Sep; 290(1-2):195-9. PubMed ID: 1915874
[TBL] [Abstract][Full Text] [Related]
13. Crystal structure of murine cyclophilin C complexed with immunosuppressive drug cyclosporin A.
Ke H; Zhao Y; Luo F; Weissman I; Friedman J
Proc Natl Acad Sci U S A; 1993 Dec; 90(24):11850-4. PubMed ID: 8265636
[TBL] [Abstract][Full Text] [Related]
14. The 3D structure of a cyclosporin analogue in water is nearly identical to the cyclophilin-bound cyclosporin conformation.
Wenger RM; France J; Bovermann G; Walliser L; Widmer A; Widmer H
FEBS Lett; 1994 Mar; 340(3):255-9. PubMed ID: 8131854
[TBL] [Abstract][Full Text] [Related]
15. The X-ray structure of (MeBm2t)1-cyclosporin complexed with cyclophilin A provides an explanation for its anomalously high immunosuppressive activity.
Mikol V; Kallen J; Walkinshaw MD
Protein Eng; 1994 May; 7(5):597-603. PubMed ID: 8073029
[TBL] [Abstract][Full Text] [Related]
16. Interaction of cyclosporin A and two cyclosporin analogs with cyclophilin: relationship between structure and binding.
Zeder-Lutz G; Van Regenmortel MH; Wenger R; Altschuh D
J Chromatogr B Biomed Appl; 1994 Dec; 662(2):301-6. PubMed ID: 7719484
[TBL] [Abstract][Full Text] [Related]
17. Molecular modeling studies in the complex between cyclophilin and cyclosporin A.
Gallion S; Ringe D
Protein Eng; 1992 Jul; 5(5):391-7. PubMed ID: 1518786
[TBL] [Abstract][Full Text] [Related]
18. Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy.
Kallen J; Spitzfaden C; Zurini MG; Wider G; Widmer H; Wüthrich K; Walkinshaw MD
Nature; 1991 Sep; 353(6341):276-9. PubMed ID: 1896075
[TBL] [Abstract][Full Text] [Related]
19. The NMR solution conformation of unligated human cyclophilin A.
Ottiger M; Zerbe O; Güntert P; Wüthrich K
J Mol Biol; 1997 Sep; 272(1):64-81. PubMed ID: 9299338
[TBL] [Abstract][Full Text] [Related]
20. The substrate-binding site in Escherichia coli cyclophilin A preferably recognizes a cis-proline isomer or a highly distorted form of the trans isomer.
Konno M; Ito M; Hayano T; Takahashi N
J Mol Biol; 1996 Mar; 256(5):897-908. PubMed ID: 8601841
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
