BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 7651416)

  • 1. Overexpression of core-binding factor alpha (CBF alpha) reverses cellular transformation by the CBF beta-smooth muscle myosin heavy chain chimeric oncoprotein.
    Hajra A; Liu PP; Speck NA; Collins FS
    Mol Cell Biol; 1995 Sep; 15(9):4980-9. PubMed ID: 7651416
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The leukemic core binding factor beta-smooth muscle myosin heavy chain (CBF beta-SMMHC) chimeric protein requires both CBF beta and myosin heavy chain domains for transformation of NIH 3T3 cells.
    Hajra A; Liu PP; Wang Q; Kelley CA; Stacy T; Adelstein RS; Speck NA; Collins FS
    Proc Natl Acad Sci U S A; 1995 Mar; 92(6):1926-30. PubMed ID: 7892201
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cytoplasmic sequestration of the polyomavirus enhancer binding protein 2 (PEBP2)/core binding factor alpha (CBFalpha) subunit by the leukemia-related PEBP2/CBFbeta-SMMHC fusion protein inhibits PEBP2/CBF-mediated transactivation.
    Kanno Y; Kanno T; Sakakura C; Bae SC; Ito Y
    Mol Cell Biol; 1998 Jul; 18(7):4252-61. PubMed ID: 9632809
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The leukemic protein core binding factor beta (CBFbeta)-smooth-muscle myosin heavy chain sequesters CBFalpha2 into cytoskeletal filaments and aggregates.
    Adya N; Stacy T; Speck NA; Liu PP
    Mol Cell Biol; 1998 Dec; 18(12):7432-43. PubMed ID: 9819429
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The chimeric protein, PEBP2 beta/CBF beta-SMMHC, disorganizes cytoplasmic stress fibers and inhibits transcriptional activation.
    Tanaka Y; Fujii M; Hayashi K; Chiba N; Akaishi T; Shineha R; Nishihira T; Satomi S; Ito Y; Watanabe T; Satake M
    Oncogene; 1998 Aug; 17(6):699-708. PubMed ID: 9715271
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia.
    Liu P; Tarlé SA; Hajra A; Claxton DF; Marlton P; Freedman M; Siciliano MJ; Collins FS
    Science; 1993 Aug; 261(5124):1041-4. PubMed ID: 8351518
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Core binding factor beta-smooth muscle myosin heavy chain chimeric protein involved in acute myeloid leukemia forms unusual nuclear rod-like structures in transformed NIH 3T3 cells.
    Wijmenga C; Gregory PE; Hajra A; Schröck E; Ried T; Eils R; Liu PP; Collins FS
    Proc Natl Acad Sci U S A; 1996 Feb; 93(4):1630-5. PubMed ID: 8643682
    [TBL] [Abstract][Full Text] [Related]  

  • 8. PEBP2 alpha B/mouse AML1 consists of multiple isoforms that possess differential transactivation potentials.
    Bae SC; Ogawa E; Maruyama M; Oka H; Satake M; Shigesada K; Jenkins NA; Gilbert DJ; Copeland NG; Ito Y
    Mol Cell Biol; 1994 May; 14(5):3242-52. PubMed ID: 8164679
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Multimerization via its myosin domain facilitates nuclear localization and inhibition of core binding factor (CBF) activities by the CBFbeta-smooth muscle myosin heavy chain myeloid leukemia oncoprotein.
    Kummalue T; Lou J; Friedman AD
    Mol Cell Biol; 2002 Dec; 22(23):8278-91. PubMed ID: 12417730
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Core-binding factor beta (CBFbeta), but not CBFbeta-smooth muscle myosin heavy chain, rescues definitive hematopoiesis in CBFbeta-deficient embryonic stem cells.
    Miller JD; Stacy T; Liu PP; Speck NA
    Blood; 2001 Apr; 97(8):2248-56. PubMed ID: 11290585
    [TBL] [Abstract][Full Text] [Related]  

  • 11. DNA-binding domain of AML1, expressed in t(8;21) and t(3;21) myeloid leukemias, inhibits PEBP2/CBF DNA-binding but is not sufficient to transform 32D cl3 myeloid cells.
    Britos-Bray M; Sacchi N; Friedman AD
    Leukemia; 1996 Jun; 10(6):984-90. PubMed ID: 8667656
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The inv(16) fusion protein associates with corepressors via a smooth muscle myosin heavy-chain domain.
    Durst KL; Lutterbach B; Kummalue T; Friedman AD; Hiebert SW
    Mol Cell Biol; 2003 Jan; 23(2):607-19. PubMed ID: 12509458
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Rearrangement of the AML1/CBFA2 gene in myeloid leukemia with the 3;21 translocation: expression of co-existing multiple chimeric genes with similar functions as transcriptional repressors, but with opposite tumorigenic properties.
    Zent C; Kim N; Hiebert S; Zhang DE; Tenen DG; Rowley JD; Nucifora G
    Curr Top Microbiol Immunol; 1996; 211():243-52. PubMed ID: 8585955
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PEBP2/CBF, the murine homolog of the human myeloid AML1 and PEBP2 beta/CBF beta proto-oncoproteins, regulates the murine myeloperoxidase and neutrophil elastase genes in immature myeloid cells.
    Nuchprayoon I; Meyers S; Scott LM; Suzow J; Hiebert S; Friedman AD
    Mol Cell Biol; 1994 Aug; 14(8):5558-68. PubMed ID: 8035830
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The AML1 gene: a transcription factor involved in the pathogenesis of myeloid and lymphoid leukemias.
    Lo Coco F; Pisegna S; Diverio D
    Haematologica; 1997; 82(3):364-70. PubMed ID: 9234595
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The core binding factor (CBF) alpha interaction domain and the smooth muscle myosin heavy chain (SMMHC) segment of CBFbeta-SMMHC are both required to slow cell proliferation.
    Cao W; Adya N; Britos-Bray M; Liu PP; Friedman AD
    J Biol Chem; 1998 Nov; 273(47):31534-40. PubMed ID: 9813068
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The chimeric genes AML1/MDS1 and AML1/EAP inhibit AML1B activation at the CSF1R promoter, but only AML1/MDS1 has tumor-promoter properties.
    Zent CS; Mathieu C; Claxton DF; Zhang DE; Tenen DG; Rowley JD; Nucifora G
    Proc Natl Acad Sci U S A; 1996 Feb; 93(3):1044-8. PubMed ID: 8577711
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular insights into PEBP2/CBF beta-SMMHC associated acute leukemia revealed from the structure of PEBP2/CBF beta.
    Goger M; Gupta V; Kim WY; Shigesada K; Ito Y; Werner MH
    Nat Struct Biol; 1999 Jul; 6(7):620-3. PubMed ID: 10404215
    [TBL] [Abstract][Full Text] [Related]  

  • 19. CBF beta-SMMHC, expressed in M4Eo AML, reduced CBF DNA-binding and inhibited the G1 to S cell cycle transition at the restriction point in myeloid and lymphoid cells.
    Cao W; Britos-Bray M; Claxton DF; Kelley CA; Speck NA; Liu PP; Friedman AD
    Oncogene; 1997 Sep; 15(11):1315-27. PubMed ID: 9315100
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Immunohistochemical analysis of CBFbeta-SMMHC protein reveals a unique nuclear localization in acute myeloid leukemia with inv(16)(p13q22).
    Zhao W; Claxton DF; Medeiros LJ; Lu D; Vadhan-Raj S; Kantarjian HM; Nguyen MH; Bueso-Ramos CE
    Am J Surg Pathol; 2006 Nov; 30(11):1436-44. PubMed ID: 17063086
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.