888 related articles for article (PubMed ID: 7658432)
1. Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors.
Hruby VJ; Lu D; Sharma SD; Castrucci AL; Kesterson RA; al-Obeidi FA; Hadley ME; Cone RD
J Med Chem; 1995 Sep; 38(18):3454-61. PubMed ID: 7658432
[TBL] [Abstract][Full Text] [Related]
2. Potent and prolonged acting cyclic lactam analogues of alpha-melanotropin: design based on molecular dynamics.
Al-Obeidi F; Castrucci AM; Hadley ME; Hruby VJ
J Med Chem; 1989 Dec; 32(12):2555-61. PubMed ID: 2555512
[TBL] [Abstract][Full Text] [Related]
3. Characterization of melanocortin receptor ligands on cloned brain melanocortin receptors and on grooming behavior in the rat.
Adan RA; Szklarczyk AW; Oosterom J; Brakkee JH; Nijenhuis WA; Schaaper WM; Meloen RH; Gispen WH
Eur J Pharmacol; 1999 Aug; 378(3):249-58. PubMed ID: 10493100
[TBL] [Abstract][Full Text] [Related]
4. Biological and conformational examination of stereochemical modifications using the template melanotropin peptide, Ac-Nle-c[Asp-His-Phe-Arg-Trp-Ala-Lys]-NH2, on human melanocortin receptors.
Haskell-Luevano C; Nikiforovich G; Sharma SD; Yang YK; Dickinson C; Hruby VJ; Gantz I
J Med Chem; 1997 May; 40(11):1738-48. PubMed ID: 9171884
[TBL] [Abstract][Full Text] [Related]
5. Design, synthesis, and biological activities of a potent and selective alpha-melanotropin antagonist.
al-Obeidi F; Hruby VJ; Hadley ME; Sawyer TK; Castrucci AM
Int J Pept Protein Res; 1990 Mar; 35(3):228-34. PubMed ID: 2162330
[TBL] [Abstract][Full Text] [Related]
6. Design of potent linear alpha-melanotropin 4-10 analogues modified in positions 5 and 10.
Al-Obeidi F; Hruby VJ; Castrucci AM; Hadley ME
J Med Chem; 1989 Jan; 32(1):174-9. PubMed ID: 2535874
[TBL] [Abstract][Full Text] [Related]
7. Identification of antagonists for melanocortin MC3, MC4 and MC5 receptors.
Adan RA; Oosterom J; Ludvigsdottir G; Brakkee JH; Burbach JP; Gispen WH
Eur J Pharmacol; 1994 Nov; 269(3):331-7. PubMed ID: 7895772
[TBL] [Abstract][Full Text] [Related]
8. Cyclic lactam analogues of Ac-[Nle4]alpha-MSH4-11-NH2.
Sugg EE; Castrucci AM; Hadley ME; van Binst G; Hruby VJ
Biochemistry; 1988 Oct; 27(21):8181-8. PubMed ID: 2852955
[TBL] [Abstract][Full Text] [Related]
9. [111In]-DTPA-labeled analogues of alpha-melanocyte-stimulating hormone for melanoma targeting: receptor binding in vitro and in vivo.
Bagutti C; Stolz B; Albert R; Bruns C; Pless J; Eberle AN
Int J Cancer; 1994 Sep; 58(5):749-55. PubMed ID: 8077062
[TBL] [Abstract][Full Text] [Related]
10. De novo design, synthesis, and pharmacology of alpha-melanocyte stimulating hormone analogues derived from somatostatin by a hybrid approach.
Han G; Haskell-Luevano C; Kendall L; Bonner G; Hadley ME; Cone RD; Hruby VJ
J Med Chem; 2004 Mar; 47(6):1514-26. PubMed ID: 14998337
[TBL] [Abstract][Full Text] [Related]
11. Three-dimensional molecular models of the hMC1R melanocortin receptor: complexes with melanotropin peptide agonists.
Haskell-Luevano C; Sawyer TK; Trumpp-Kallmeyer S; Bikker JA; Humblet C; Gantz I; Hruby VJ
Drug Des Discov; 1996 Dec; 14(3):197-211. PubMed ID: 9017363
[TBL] [Abstract][Full Text] [Related]
12. Molecular basis for the interaction of [Nle4,D-Phe7]melanocyte stimulating hormone with the human melanocortin-1 receptor.
Yang Yk; Dickinson C; Haskell-Luevano C; Gantz I
J Biol Chem; 1997 Sep; 272(37):23000-10. PubMed ID: 9287296
[TBL] [Abstract][Full Text] [Related]
13. Selectivity of cyclic [D-Nal7] and [D-Phe7] substituted MSH analogues for the melanocortin receptor subtypes.
Schiöth HB; Müceniece R; Mutulis F; Prusis P; Lindeberg G; Sharma SD; Hruby VJ; Wikberg JE
Peptides; 1997; 18(7):1009-13. PubMed ID: 9357059
[TBL] [Abstract][Full Text] [Related]
14. Potent and prolonged melanotropic activities of the alpha-MSH fragment analog, Ac-[Nle4,D-Phe7]-alpha-MSH4-9-NH2.
Klemes DG; Kreutzfeld KL; Hadley ME; Cody WL; Hruby VJ
Biochem Biophys Res Commun; 1986 Jun; 137(2):722-8. PubMed ID: 3089218
[TBL] [Abstract][Full Text] [Related]
15. Characterisation of melanocortin receptor subtypes by radioligand binding analysis.
Schiöth HB; Muceniece R; Wikberg JE; Chhajlani V
Eur J Pharmacol; 1995 Feb; 288(3):311-7. PubMed ID: 7774675
[TBL] [Abstract][Full Text] [Related]
16. Structure-activity studies of the melanocortin peptides: discovery of potent and selective affinity antagonists for the hMC3 and hMC4 receptors.
Grieco P; Lavecchia A; Cai M; Trivedi D; Weinberg D; MacNeil T; Van der Ploeg LH; Hruby VJ
J Med Chem; 2002 Nov; 45(24):5287-94. PubMed ID: 12431055
[TBL] [Abstract][Full Text] [Related]
17. Characterization of melanocortin receptor subtype expression in murine adipose tissues and in the 3T3-L1 cell line.
Boston BA; Cone RD
Endocrinology; 1996 May; 137(5):2043-50. PubMed ID: 8612546
[TBL] [Abstract][Full Text] [Related]
18. Cyclic analogs of alpha-melanocyte-stimulating hormone (alphaMSH) with high agonist potency and selectivity at human melanocortin receptor 1b.
Bednarek MA; MacNeil T; Tang R; Fong TM; Cabello MA; Maroto M; Teran A
Peptides; 2008 Jun; 29(6):1010-7. PubMed ID: 18378043
[TBL] [Abstract][Full Text] [Related]
19. Characterizations of the unusual dissociation properties of melanotropin peptides from the melanocortin receptor, hMC1R.
Haskell-Luevano C; Miwa H; Dickinson C; Hadley ME; Hruby VJ; Yamada T; Gantz I
J Med Chem; 1996 Jan; 39(2):432-5. PubMed ID: 8558511
[TBL] [Abstract][Full Text] [Related]
20. Discovery of novel melanocortin4 receptor selective MSH analogues.
Schiöth HB; Mutulis F; Muceniece R; Prusis P; Wikberg JE
Br J Pharmacol; 1998 May; 124(1):75-82. PubMed ID: 9630346
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
