These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

132 related articles for article (PubMed ID: 7660870)

  • 1. Comparison of 5-fluoro-2'-deoxyuridine and 5-fluorouracil in the treatment of murine colon cancer; effects on thymidylate synthase.
    van der Wilt CL; van Laar JA; Smid K; Rustum YM; Peters GJ
    Adv Exp Med Biol; 1994; 370():109-14. PubMed ID: 7660870
    [No Abstract]   [Full Text] [Related]  

  • 2. Therapeutic efficacy of fluoropyrimidines depends on the duration of thymidylate synthase inhibition in the murine colon 26-B carcinoma tumor model.
    van Laar JA; van der Wilt CL; Rustum YM; Noordhuis P; Smid K; Pinedo HM; Peters GJ
    Clin Cancer Res; 1996 Aug; 2(8):1327-33. PubMed ID: 9816304
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In vivo antitumor effects of fluoropyrimidines on colon adenocarcinoma 38 and enhancement by leucovorin.
    Iigo M; Nishikata K; Hoshi A
    Jpn J Cancer Res; 1992 Apr; 83(4):392-6. PubMed ID: 1387127
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Isolated liver perfusion versus hepatic artery infusion with 5-fluorouracil in a rat model; effects on thymidylate synthase.
    Van der Wilt CL; Marinelli A; Cloos J; Smid K; Pinedo HM; Peters GJ
    Adv Exp Med Biol; 1991; 309A():105-8. PubMed ID: 1789186
    [No Abstract]   [Full Text] [Related]  

  • 5. Effect of folinic acid on fluorouracil activity and expression of thymidylate synthase.
    van der Wilt CL; Pinedo HM; Smid K; Cloos J; Noordhuis P; Peters GJ
    Semin Oncol; 1992 Apr; 19(2 Suppl 3):16-25. PubMed ID: 1532671
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thymidylate synthetase activity and fluorouracil sensitivity of human colonic cancer and normal mucosal tissue preparations.
    Wolberg WH; Morin J
    Cancer; 1981 Mar; 47(6):1313-7. PubMed ID: 7226054
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enzymatic conversion of 5-fluoro-2'-deoxyuridine to 5-fluorouracil or 5-fluoro-2'-deoxyuridine 5'-monophosphate in human tissues.
    Uchida M; Brown N; Ho DH
    Anticancer Res; 1990; 10(3):779-83. PubMed ID: 2142396
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of thymidylate synthase in human colon cancer cells treated with 5-fluorouracil and interferon-gamma.
    Chu E; Allegra CJ
    Adv Exp Med Biol; 1993; 339():143-51; discussion 165-7. PubMed ID: 8178713
    [No Abstract]   [Full Text] [Related]  

  • 9. Thymidylate synthase level as the main predictive parameter for sensitivity to 5-fluorouracil, but not for folate-based thymidylate synthase inhibitors, in 13 nonselected colon cancer cell lines.
    van Triest B; Pinedo HM; van Hensbergen Y; Smid K; Telleman F; Schoenmakers PS; van der Wilt CL; van Laar JA; Noordhuis P; Jansen G; Peters GJ
    Clin Cancer Res; 1999 Mar; 5(3):643-54. PubMed ID: 10100718
    [TBL] [Abstract][Full Text] [Related]  

  • 10. On the mechanism of cytotoxicity of fluorinated pyrimidines in four human colon adenocarcinoma xenografts maintained in immune-deprived mice.
    Houghton JA; Houghton PJ
    Cancer; 1980 Mar; 45(5 Suppl):1159-67. PubMed ID: 6444543
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas.
    Spears CP; Shahinian AH; Moran RG; Heidelberger C; Corbett TH
    Cancer Res; 1982 Feb; 42(2):450-6. PubMed ID: 6173112
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mechanisms of resistance to fluoropyrimidines.
    Zhang ZG; Harstrick A; Rustum YM
    Semin Oncol; 1992 Apr; 19(2 Suppl 3):4-9. PubMed ID: 1532673
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 18F-radiopharmacokinetics of [18F]-5-fluorouracil in a mouse bearing two colon tumors with a different 5-fluorouracil sensitivity: a study for a correlation with oncological results.
    Visser GW; van der Wilt CL; Wedzinga R; Peters GJ; Herscheid JD
    Nucl Med Biol; 1996 Apr; 23(3):333-42. PubMed ID: 8782245
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Pharmacodynamics of 5-fluorouracil and leucovorin.
    Gustavsson BG; Carlsson G; Frösing R; Spears CP
    Adv Exp Med Biol; 1988; 244():219-24. PubMed ID: 3266824
    [No Abstract]   [Full Text] [Related]  

  • 15. A method for the determination of total, free, and 5-fluorodeoxyuridylate-bound thymidylate synthase in cell extracts.
    Fernandes DJ; Cranford SK
    Anal Biochem; 1984 Nov; 142(2):378-85. PubMed ID: 6241433
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Potentiation of 5-fluorouracil induced inhibition of thymidylate synthase in human colon tumors by leucovorin is dose dependent.
    Peters GJ; Hoekman K; van Groeningen CJ; van der Wilt CL; Smid K; Meijer S; Pinedo HM
    Adv Exp Med Biol; 1993; 338():613-6. PubMed ID: 8304192
    [No Abstract]   [Full Text] [Related]  

  • 17. Tumor 5-fluorodeoxyuridylate concentration as a determinant of 5-fluorouracil response.
    Ardalan B; Buscaglia MD; Schein PS
    Biochem Pharmacol; 1978; 27(16):2009-13. PubMed ID: 718724
    [No Abstract]   [Full Text] [Related]  

  • 18. Determination of thymidylate synthase activity in colon tumor tissues after treatment with 5-fluorouracil.
    Houghton JA; Radparvar S; Torrance PM; Williams LG; Houghton PJ
    Biochem Pharmacol; 1987 Apr; 36(8):1285-9. PubMed ID: 3593415
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Leucovorin enhancement of the effects of the fluoropyrimidines on thymidylate synthase.
    Morgan RG
    Cancer; 1989 Mar; 63(6 Suppl):1008-12. PubMed ID: 2521810
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biochemical determinants of responsiveness to 5-fluorouracil and its derivatives in xenografts of human colorectal adenocarcinomas in mice.
    Houghton JA; Maroda SJ; Phillips JO; Houghton PJ
    Cancer Res; 1981 Jan; 41(1):144-9. PubMed ID: 7448754
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.