These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

102 related articles for article (PubMed ID: 7660882)

  • 1. Pharmacokinetics/pharmacodynamics of CI-1000, a purine nucleoside phosphorylase (PNP) inhibitor, in rats and monkeys.
    Hallak H; Hayes A; Dong M; Gilbertsen R; Guttendorf R
    Adv Exp Med Biol; 1994; 370():161-5. PubMed ID: 7660882
    [No Abstract]   [Full Text] [Related]  

  • 2. Blockade of nucleoside degradation in monkey whole blood in vitro by CI-1000, a purine nucleoside phosphorylase (PNP) inhibitor.
    Gilbertsen RB; Dong MK
    Adv Exp Med Biol; 1994; 370():167-71. PubMed ID: 7660883
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Changes in monkey plasma purines induced by repeated doses of CI-1000, a novel inhibitor of purine nucleoside phosphorylase.
    Robertson DG; Urda ER; Bleavins MR; Lalwani ND
    Adv Exp Med Biol; 1994; 370():173-7. PubMed ID: 7660884
    [No Abstract]   [Full Text] [Related]  

  • 4. The biochemical and pharmacological activity of 9-benzyl-9-deazaguanine, a potent purine nucleoside phosphorylase (PNP) inhibitor.
    Kimble E; Hadala J; Ludewig R; Peters P; Greenberg G; Xiao G; Guida W; McQuire L; Simon P
    Inflamm Res; 1995 Aug; 44 Suppl 2():S181-2. PubMed ID: 8548387
    [No Abstract]   [Full Text] [Related]  

  • 5. Comparative in vitro and in vivo activities of two 9-deazaguanine analog inhibitors of purine nucleoside phosphorylase, CI-972 and PD 141955.
    Gilbertsen RB; Josyula U; Sircar JC; Dong MK; Wu WS; Wilburn DJ; Conroy MC
    Biochem Pharmacol; 1992 Sep; 44(5):996-9. PubMed ID: 1530667
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Pharmacokinetics and pharmacodynamics of peldesine (BCX-34), a purine nucleoside phosphorylase inhibitor, following single and multiple oral doses in healthy volunteers.
    Viegas TX; Omura GA; Stoltz RR; Kisicki J
    J Clin Pharmacol; 2000 Apr; 40(4):410-20. PubMed ID: 10761169
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Purine nucleoside phosphorylase inhibitors: biochemical and pharmacological studies with 9-benzyl-9-deazaguanine and related compounds.
    Bennett LL; Allan PW; Noker PE; Rose LM; Niwas S; Montgomery JA; Erion MD
    J Pharmacol Exp Ther; 1993 Aug; 266(2):707-14. PubMed ID: 8355201
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Purine nucleoside phosphorylase as a cytosolic arsenate reductase.
    Gregus Z; Németi B
    Toxicol Sci; 2002 Nov; 70(1):13-9. PubMed ID: 12388830
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitors of human purine nucleoside phosphorylase. Synthesis, purine nucleoside phosphorylase inhibition, and T-cell cytotoxicity of 2,5-diaminothiazolo[5,4-d]pyrimidin-7(6H)-one and 2,5-diaminothiazolo[4,5-d]pyrimidin-7(6H)-one. Two thio isosteres of 8-aminoguanine.
    Sircar JC; Suto MJ; Scott ME; Dong MK; Gilbertsen RB
    J Med Chem; 1986 Sep; 29(9):1804-6. PubMed ID: 3091835
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 8-Amino-9-substituted guanines: potent purine nucleoside phosphorylase (PNP) inhibitors.
    Sircar JC; Kostlan CR; Pinter GW; Suto MJ; Bobovski TP; Capiris T; Schwender CF; Dong MK; Scott ME; Bennett MK
    Agents Actions; 1987 Aug; 21(3-4):253-6. PubMed ID: 3120506
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Nucleosides. 5. Synthesis of guanine and formycin B derivatives as potential inhibitors of purine nucleoside phosphorylase.
    Chern JW; Lee HY; Chen CS; Shewach DS; Daddona PE; Townsend LB
    J Med Chem; 1993 Apr; 36(8):1024-31. PubMed ID: 8478902
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibitors of purine nucleoside phosphorylase, C(8) and C(5') substitutions.
    Stoeckler JD; Cambor C; Kuhns V; Chu SH; Parks RE
    Biochem Pharmacol; 1982 Jan; 31(2):163-71. PubMed ID: 6800381
    [No Abstract]   [Full Text] [Related]  

  • 13. PD 141955 and CI-972: 9-deazaguanine analog purine nucleoside phosphorylase inhibitors. II. Effects on nucleoside catabolism in human and rat blood in vitro.
    Dong MK; Gilbertsen RB
    Agents Actions; 1993; 39 Spec No():C99-101. PubMed ID: 8273600
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The biochemistry and pharmacology of PD 116124 (8-amino-2'-nordeoxyguanosine), an inhibitor of purine nucleoside phosphorylase (PNP).
    Dong MK; Scott ME; Schrier DJ; Suto MJ; Sircar JC; Black A; Chang T; Gilbertsen RB
    J Pharmacol Exp Ther; 1992 Jan; 260(1):319-26. PubMed ID: 1530976
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Potentiation of 2'-deoxyguanosine cytotoxicity by a novel inhibitor of purine nucleoside phosphorylase, 8-amino-9-benzylguanine.
    Shewach DS; Chern JW; Pillote KE; Townsend LB; Daddona PE
    Cancer Res; 1986 Feb; 46(2):519-23. PubMed ID: 3079664
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structure-based design of inhibitors of purine nucleoside phosphorylase. 2. 9-Alicyclic and 9-heteroalicyclic derivatives of 9-deazaguanine.
    Secrist JA; Niwas S; Rose JD; Babu YS; Bugg CE; Erion MD; Guida WC; Ealick SE; Montgomery JA
    J Med Chem; 1993 Jun; 36(13):1847-54. PubMed ID: 8515423
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 8-Aminoguanine Induces Diuresis, Natriuresis, and Glucosuria by Inhibiting Purine Nucleoside Phosphorylase and Reduces Potassium Excretion by Inhibiting Rac1.
    Jackson EK; Mi Z; Kleyman TR; Cheng D
    J Am Heart Assoc; 2018 Nov; 7(21):e010085. PubMed ID: 30608204
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activities of two 9-deazaguanine analogue inhibitors of purine nucleoside phosphorylase, CI-972 and PD 141955, in vitro and in vivo.
    Gilbertsen RB; Dong MK; Josyula U; Sircar JC; Wilburn DJ; Conroy MC
    Ann N Y Acad Sci; 1993 Jun; 685():248-51. PubMed ID: 8363228
    [No Abstract]   [Full Text] [Related]  

  • 19. Inhibitors of the enzyme purine nucleoside phosphorylase as potential therapy for psoriasis.
    Morris PE; Omura GA
    Curr Pharm Des; 2000 Jun; 6(9):943-59. PubMed ID: 10828318
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-based design of inhibitors of purine nucleoside phosphorylase. 3. 9-Arylmethyl derivatives of 9-deazaguanine substituted on the methylene group.
    Erion MD; Niwas S; Rose JD; Ananthan S; Allen M; Secrist JA; Babu YS; Bugg CE; Guida WC; Ealick SE
    J Med Chem; 1993 Nov; 36(24):3771-83. PubMed ID: 8254607
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.