195 related articles for article (PubMed ID: 7660885)
1. Inhibitors of thymidylate synthase and glycinamide ribonucleotide transformylase.
Jackson RC
Adv Exp Med Biol; 1994; 370():179-83. PubMed ID: 7660885
[No Abstract] [Full Text] [Related]
2. Newer antifolates in cancer therapy.
Schultz RM
Prog Drug Res; 1995; 44():129-57. PubMed ID: 7644664
[No Abstract] [Full Text] [Related]
3. Conformationally restricted analogues designed for selective inhibition of GAR Tfase versus thymidylate synthase or dihydrofolate reductase.
Boger DL; Labroli MA; Marsilje TH; Jin Q; Hedrick MP; Baker SJ; Shim JH; Benkovic SJ
Bioorg Med Chem; 2000 May; 8(5):1075-86. PubMed ID: 10882019
[TBL] [Abstract][Full Text] [Related]
4. LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes.
Shih C; Chen VJ; Gossett LS; Gates SB; MacKellar WC; Habeck LL; Shackelford KA; Mendelsohn LG; Soose DJ; Patel VF; Andis SL; Bewley JR; Rayl EA; Moroson BA; Beardsley GP; Kohler W; Ratnam M; Schultz RM
Cancer Res; 1997 Mar; 57(6):1116-23. PubMed ID: 9067281
[TBL] [Abstract][Full Text] [Related]
5. On the cofactor specificity of glycinamide ribonucleotide and 5-aminoimidazole-4-carboxamide ribonucleotide transformylase from chicken liver.
Smith GK; Mueller WT; Benkovic PA; Benkovic SJ
Biochemistry; 1981 Mar; 20(5):1241-5. PubMed ID: 7225325
[TBL] [Abstract][Full Text] [Related]
6. Inhibition of folate-dependent enzymes by 7-OH-methotrexate.
Sholar PW; Baram J; Seither R; Allegra CJ
Biochem Pharmacol; 1988 Sep; 37(18):3531-4. PubMed ID: 2458733
[No Abstract] [Full Text] [Related]
7. Tetrahydrohomofolate polyglutamates as inhibitors of thymidylate synthase and glycinamide ribonucleotide formyltransferase in Lactobacillus casei.
Thorndike J; Kisliuk RL; Gaumont Y; Piper JR; Nair MG
Arch Biochem Biophys; 1990 Mar; 277(2):334-41. PubMed ID: 2106831
[TBL] [Abstract][Full Text] [Related]
8. N10-substituted 5,8-dideazafolate inhibitors of glycinamide ribonucleotide transformylase.
Caperelli CA
J Med Chem; 1987 Jul; 30(7):1254-6. PubMed ID: 3599031
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and biological evaluation of 8-deazahomofolic acid and its tetrahydro derivative.
DeGraw JI; Colwell WT; Brown VH; Sato M; Kisliuk RL; Gaumont Y; Thorndike J; Sirotnak FM
J Med Chem; 1988 Jan; 31(1):150-3. PubMed ID: 3121855
[TBL] [Abstract][Full Text] [Related]
10. Carrier- and receptor-mediated transport of folate antagonists targeting folate-dependent enzymes: correlates of molecular-structure and biological activity.
Westerhof GR; Schornagel JH; Kathmann I; Jackman AL; Rosowsky A; Forsch RA; Hynes JB; Boyle FT; Peters GJ; Pinedo HM
Mol Pharmacol; 1995 Sep; 48(3):459-71. PubMed ID: 7565626
[TBL] [Abstract][Full Text] [Related]
11. Cell cycle effects of antifolate antimetabolites: implications for cytotoxicity and cytostasis.
Tonkinson JL; Marder P; Andis SL; Schultz RM; Gossett LS; Shih C; Mendelsohn LG
Cancer Chemother Pharmacol; 1997; 39(6):521-31. PubMed ID: 9118464
[TBL] [Abstract][Full Text] [Related]
12. Biochemical and biological studies on 2-desamino-2-methylaminopterin, an antifolate the polyglutamates of which are more potent than the monoglutamate against three key enzymes of folate metabolism.
Rosowsky A; Galivan J; Beardsley GP; Bader H; O'Connor BM; Russello O; Moroson BA; DeYarman MT; Kerwar SS; Freisheim JH
Cancer Res; 1992 Apr; 52(8):2148-55. PubMed ID: 1313737
[TBL] [Abstract][Full Text] [Related]
13. Synthesis of 10-acetyl-5,8-dideazafolic acid: a potent inhibitor of glycinamide ribonucleotide transformylase.
Caperelli CA; Conigliaro J
J Med Chem; 1986 Oct; 29(10):2117-9. PubMed ID: 3761327
[TBL] [Abstract][Full Text] [Related]
14. Synthesis and biological activity of an acyclic analogue of 5,6,7,8-tetrahydrofolic acid, N-[4-[[3-(2,4-diamino-1,6-dihydro-6-oxo-5- pyrimidinyl)propyl]amino]-benzoyl]-L-glutamic acid.
Kelley JL; McLean EW; Cohn NK; Edelstein MP; Duch DS; Smith GK; Hanlon MH; Ferone R
J Med Chem; 1990 Feb; 33(2):561-7. PubMed ID: 2299624
[TBL] [Abstract][Full Text] [Related]
15. Antifolates in clinical development.
Takimoto CH
Semin Oncol; 1997 Oct; 24(5 Suppl 18):S18-40-S18-51. PubMed ID: 9420020
[TBL] [Abstract][Full Text] [Related]
16. Deaza analogs of folic acid as antitumor agents.
Kisliuk RL
Curr Pharm Des; 2003; 9(31):2615-25. PubMed ID: 14529545
[TBL] [Abstract][Full Text] [Related]
17. Folate status and the safety profile of antifolates.
Calvert H
Semin Oncol; 2002 Apr; 29(2 Suppl 5):3-7. PubMed ID: 12023786
[TBL] [Abstract][Full Text] [Related]
18. Carbocyclic glycinamide ribonucleotide is a substrate for glycinamide ribonucleotide transformylase.
Caperelli CA; Price MF
Arch Biochem Biophys; 1988 Jul; 264(1):340-2. PubMed ID: 3395127
[TBL] [Abstract][Full Text] [Related]
19. Cytotoxicity of antifolate inhibitors of thymidylate and purine synthesis to WiDr colonic carcinoma cells.
Smith SG; Lehman NL; Moran RG
Cancer Res; 1993 Dec; 53(23):5697-706. PubMed ID: 8242626
[TBL] [Abstract][Full Text] [Related]
20. Antifolates: the next millennium.
Allegra CJ
Semin Oncol; 1999 Apr; 26(2 Suppl 6):1-2. PubMed ID: 10598548
[No Abstract] [Full Text] [Related]
[Next] [New Search]