These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

206 related articles for article (PubMed ID: 7662121)

  • 1. Differential mutagenicity and cytotoxicity of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol and (+/-)-anti-benzo[a]pyrene-trans-7,8-dihydrodiol-9,10-epoxide in genetically engineered human fibroblasts.
    Quan T; Reiners JJ; Culp SJ; Richter P; States JC
    Mol Carcinog; 1995 Feb; 12(2):91-102. PubMed ID: 7662121
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Expression of human cytochrome P450 1A1 in DNA repair deficient and proficient human fibroblasts stably transformed with an inducible expression vector.
    States JC; Quan T; Hines RN; Novak RF; Runge-Morris M
    Carcinogenesis; 1993 Aug; 14(8):1643-9. PubMed ID: 8353849
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cytotoxicity and genotoxicity of (+/-)-benzo[a]pyrene-trans-7,8-dihydrodiol in CYP1A1-expressing human fibroblasts quantitatively correlate with CYP1A1 expression level.
    Quan T; Reiners JJ; Bell AO; Hong N; States JC
    Carcinogenesis; 1994 Sep; 15(9):1827-32. PubMed ID: 7923575
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Expression of human glutathione S-transferase P1 confers resistance to benzo[a]pyrene or benzo[a]pyrene-7,8-dihydrodiol mutagenesis, macromolecular alkylation and formation of stable N2-Gua-BPDE adducts in stably transfected V79MZ cells co-expressing hCYP1A1.
    Kushman ME; Kabler SL; Fleming MH; Ravoori S; Gupta RC; Doehmer J; Morrow CS; Townsend AJ
    Carcinogenesis; 2007 Jan; 28(1):207-14. PubMed ID: 16885195
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The role of the Ah receptor and p38 in benzo[a]pyrene-7,8-dihydrodiol and benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced apoptosis.
    Chen S; Nguyen N; Tamura K; Karin M; Tukey RH
    J Biol Chem; 2003 May; 278(21):19526-33. PubMed ID: 12637498
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Preferential DNA damage in the p53 gene by benzo[a]pyrene metabolites in cytochrome P4501A1-expressing xeroderma pigmentosum group A cells.
    Quan T; States JC
    Mol Carcinog; 1996 May; 16(1):32-43. PubMed ID: 8634092
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vivo formation and persistence of DNA adducts in mouse and rat skin exposed to (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene and (+/-)-7 beta,8 alpha-dihydroxy-9 alpha,10 alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.
    Rojas M; Alexandrov K
    Carcinogenesis; 1986 Sep; 7(9):1553-60. PubMed ID: 3091285
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification and quantitation of benzo[a]pyrene-DNA adducts formed by rat liver microsomes in vitro.
    Devanesan PD; RamaKrishna NV; Todorovic R; Rogan EG; Cavalieri EL; Jeong H; Jankowiak R; Small GJ
    Chem Res Toxicol; 1992; 5(2):302-9. PubMed ID: 1643262
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differences in the rate of DNA adduct removal and the efficiency of mutagenesis for two benzo[a]pyrene diol epoxides in CHO cells.
    MacLeod MC; Daylong A; Adair G; Humphrey RM
    Mutat Res; 1991 Dec; 261(4):267-79. PubMed ID: 1722282
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Low absolute mutagenic efficiency but high cytotoxicity of a non-bay region diol epoxide derived from benzo[a]pyrene.
    MacLeod MC; Adair G; Daylong A; Lew L; Humphrey RM
    Mutat Res; 1991 Dec; 261(4):281-93. PubMed ID: 1722283
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Preferential repair and strand-specific repair of benzo[a]pyrene diol epoxide adducts in the HPRT gene of diploid human fibroblasts.
    Chen RH; Maher VM; Brouwer J; van de Putte P; McCormick JJ
    Proc Natl Acad Sci U S A; 1992 Jun; 89(12):5413-7. PubMed ID: 1608950
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolic activation of racemic and enantiomeric trans-8, 9-dihydroxy-8,9-dihydrodibenzo[a,l]pyrene (dibenzo[def,p]chrysene) to dibenzo[a,l]pyrene-bis-dihydrodiols by induced rat liver microsomes and a recombinant human P450 1A1 system: the role of the K-region-derived metabolic intermediates in the formation of dibenzo[a,l]pyrene-DNA adducts.
    Nesnow S; Davis C; Padgett W; George M; Lambert G; Meyers F; Allison J; Adams L; King LC
    Chem Res Toxicol; 1998 Dec; 11(12):1596-607. PubMed ID: 9860506
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Protective efficacy of hGSTM1-1 against B[a]P and (+)- or (-)-B[a]P-7,8-dihydrodiol cytotoxicity, mutagenicity, and macromolecular adducts in V79 cells coexpressing hCYP1A1.
    Kushman ME; Kabler SL; Ahmad S; Doehmer J; Morrow CS; Townsend AJ
    Toxicol Sci; 2007 Sep; 99(1):51-7. PubMed ID: 17525473
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Trans- and cis-DNA adduct concentration in epidermis from mouse and rat skin treated ex vivo with benzo[a]pyrene diol epoxide and its corresponding chlorohydrin.
    Vock EH; Wolfe AR; Meehan T
    Mutat Res; 2001 Jul; 478(1-2):199-206. PubMed ID: 11406185
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Separation of (+)-syn- and (-)-anti-benzo[a]pyrene dihydrodiol epoxide-DNA adducts in 32P-postlabeling analysis.
    Reddy AP; Pruess-Schwartz D; Marnett LJ
    Chem Res Toxicol; 1992; 5(1):19-25. PubMed ID: 1581531
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Supercoiled DNA promotes formation of intercalated cis-N2-deoxyguanine adducts and base-stacked trans-N2-deoxyguanine adducts by (+)-7R,8S-dihydrodiol-9S,10R-epoxy-7,8,9,10-tetra- hydrobenzo[a]pyrene.
    Jiang G; Jankowiak R; Grubor N; Banasiewicz M; Small GJ; Skorvaga M; Van Houten B; States JC
    Chem Res Toxicol; 2004 Mar; 17(3):330-9. PubMed ID: 15025503
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Site-specific rates of excision repair of benzo[a]pyrene diol epoxide adducts in the hypoxanthine phosphoribosyltransferase gene of human fibroblasts: correlation with mutation spectra.
    Wei D; Maher VM; McCormick JJ
    Proc Natl Acad Sci U S A; 1995 Mar; 92(6):2204-8. PubMed ID: 7892248
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Relationship between adduct formation, rates of excision repair and the cytotoxic and mutagenic effects of structurally-related polycyclic aromatic carcinogens.
    McGregor WG; Wei D; Chen RH; Maher VM; McCormick JJ
    Mutat Res; 1997 May; 376(1-2):143-52. PubMed ID: 9202750
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Differential efficiency of mutagenesis at three genetic loci in CHO cells by a benzo[a]pyrene diol epoxide.
    MacLeod MC; Adair G; Humphrey RM
    Mutat Res; 1988 May; 199(1):243-54. PubMed ID: 3129654
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Induction of DNA adducts and mutations in spleen, liver and lung of XPA-deficient/lacZ transgenic mice after oral treatment with benzo[a]pyrene: correlation with tumour development.
    de Vries A; Dollé ME; Broekhof JL; Muller JJ; Kroese ED; van Kreijl CF; Capel PJ; Vijg J; van Steeg H
    Carcinogenesis; 1997 Dec; 18(12):2327-32. PubMed ID: 9450477
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.