These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

148 related articles for article (PubMed ID: 7682567)

  • 1. Stable transfectants of human MCF-7 breast cancer cells with increased levels of the human folate receptor exhibit an increased sensitivity to antifolates.
    Chung KN; Saikawa Y; Paik TH; Dixon KH; Mulligan T; Cowan KH; Elwood PC
    J Clin Invest; 1993 Apr; 91(4):1289-94. PubMed ID: 7682567
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rapid turnover and impaired cell-surface expression of the human folate receptor in mouse L(tk-) fibroblasts, a cell line defective in glycosylphosphatidylinositol tail synthesis.
    Chung KN; Roberts S; Kim CH; Kirassova M; Trepel J; Elwood PC
    Arch Biochem Biophys; 1995 Sep; 322(1):228-34. PubMed ID: 7574680
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Functional activity of the reduced folate carrier in KB, MA104, and IGROV-I cells expressing folate-binding protein.
    Westerhof GR; Rijnboutt S; Schornagel JH; Pinedo HM; Peters GJ; Jansen G
    Cancer Res; 1995 Sep; 55(17):3795-802. PubMed ID: 7641196
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of a membrane-associated folate-binding protein in human leukemic CCRF-CEM cells with transport-related methotrexate resistance.
    Jansen G; Westerhof GR; Kathmann I; Rademaker BC; Rijksen G; Schornagel JH
    Cancer Res; 1989 May; 49(9):2455-9. PubMed ID: 2706633
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Decreased expression of the human folate receptor mediates transport-defective methotrexate resistance in KB cells.
    Saikawa Y; Knight CB; Saikawa T; Page ST; Chabner BA; Elwood PC
    J Biol Chem; 1993 Mar; 268(7):5293-301. PubMed ID: 7680349
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of membrane-associated folate binding protein in the cytotoxicity of antifolates in KB, IGROV1, and L1210A cells.
    Schultz RM; Andis SL; Shackelford KA; Gates SB; Ratnam M; Mendelsohn LG; Shih C; Grindey GB
    Oncol Res; 1995; 7(2):97-102. PubMed ID: 7579732
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Multiple mechanisms of resistance to polyglutamatable and lipophilic antifolates in mammalian cells: role of increased folylpolyglutamylation, expanded folate pools, and intralysosomal drug sequestration.
    Jansen G; Barr H; Kathmann I; Bunni MA; Priest DG; Noordhuis P; Peters GJ; Assaraf YG
    Mol Pharmacol; 1999 Apr; 55(4):761-9. PubMed ID: 10101035
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Functional aspects of membrane folate receptors in human breast cancer cells with transport-related resistance to methotrexate.
    Pinard MF; Jolivet J; Ratnam M; Kathmann I; Molthoff C; Westerhof R; Schornagel JH; Jansen G
    Cancer Chemother Pharmacol; 1996; 38(3):281-8. PubMed ID: 8646804
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Isolation of a gene encoding a human reduced folate carrier (RFC1) and analysis of its expression in transport-deficient, methotrexate-resistant human breast cancer cells.
    Moscow JA; Gong M; He R; Sgagias MK; Dixon KH; Anzick SL; Meltzer PS; Cowan KH
    Cancer Res; 1995 Sep; 55(17):3790-4. PubMed ID: 7641195
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Site-directed mutagenesis of tryptophan residues to conserved hydrophobic residues inhibits the processing of human KB cell folate receptor.
    Chung KN; Paik TH; Roberts S; Kim CH; Kirassova M; Weinstein JN; Trepel JB; Elwood PC
    Arch Biochem Biophys; 1994 Dec; 315(2):407-14. PubMed ID: 7986085
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Folate-binding protein mRNA is decreased in methotrexate-resistant KB cells.
    Hsueh CT; Dolnick BJ
    Oncol Res; 1992; 4(11-12):497-505. PubMed ID: 1299378
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The divergent 5' termini of the alpha human folate receptor (hFR) mRNAs originate from two tissue-specific promoters and alternative splicing: characterization of the alpha hFR gene structure.
    Elwood PC; Nachmanoff K; Saikawa Y; Page ST; Pacheco P; Roberts S; Chung KN
    Biochemistry; 1997 Feb; 36(6):1467-78. PubMed ID: 9063895
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Folate receptor beta as a potential delivery route for novel folate antagonists to macrophages in the synovial tissue of rheumatoid arthritis patients.
    van der Heijden JW; Oerlemans R; Dijkmans BA; Qi H; van der Laken CJ; Lems WF; Jackman AL; Kraan MC; Tak PP; Ratnam M; Jansen G
    Arthritis Rheum; 2009 Jan; 60(1):12-21. PubMed ID: 19116913
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Sensitivity to 5,10-dideazatetrahydrofolate is fully conserved in a murine leukemia cell line highly resistant to methotrexate due to impaired transport mediated by the reduced folate carrier.
    Zhao R; Gao F; Babani S; Goldman ID
    Clin Cancer Res; 2000 Aug; 6(8):3304-11. PubMed ID: 10955817
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Contrasting effects of oncogene expression on two carrier-mediated systems internalizing folate compounds in Fisher rat 3T3 cells.
    Kühnel JM; Chiao JH; Sirotnak FM
    J Cell Physiol; 2000 Sep; 184(3):364-72. PubMed ID: 10911368
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Determinants of activity of the antifolate thymidylate synthase inhibitors Tomudex (ZD1694) and GW1843U89 against mono- and multilayered colon cancer cell lines under folate-restricted conditions.
    Peters GJ; Smitskamp-Wilms E; Smid K; Pinedo HM; Jansen G
    Cancer Res; 1999 Nov; 59(21):5529-35. PubMed ID: 10554030
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of a folate transporter in HeLa cells with a low pH optimum and high affinity for pemetrexed distinct from the reduced folate carrier.
    Wang Y; Zhao R; Goldman ID
    Clin Cancer Res; 2004 Sep; 10(18 Pt 1):6256-64. PubMed ID: 15448015
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Membrane transport of methotrexate in a squamous carcinoma cell line adapted to low folate concentrations.
    van der Laan BF; Jansen G; van Gestel JA; Schornagel JH; Hordijk GJ
    Anticancer Res; 1991; 11(3):1265-8. PubMed ID: 1888158
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Novel 6,5-fused ring heterocyclic antifolates: biochemical and biological characterization.
    McGuire JJ; Bergoltz VV; Heitzman KJ; Haile WH; Russell CA; Bolanowska WE; Kotake Y; Haneda T; Nomura H
    Cancer Res; 1994 May; 54(10):2673-9. PubMed ID: 8168096
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Recent advances in the understanding of the mechanism of membrane transport of folates and antifolates.
    Sierra EE; Goldman ID
    Semin Oncol; 1999 Apr; 26(2 Suppl 6):11-23. PubMed ID: 10598550
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.