161 related articles for article (PubMed ID: 7687120)
21. Inhibition of Pneumocystis carinii, Toxoplasma gondii, and Mycobacterium avium dihydrofolate reductases by 2,4-diamino-5-[2-methoxy-5-(omega-carboxyalkyloxy)benzyl]pyrimidines: marked improvement in potency relative to trimethoprim and species selectivity relative to piritrexim.
Rosowsky A; Forsch RA; Queener SF
J Med Chem; 2002 Jan; 45(1):233-41. PubMed ID: 11754594
[TBL] [Abstract][Full Text] [Related]
22. Inosiplex: metabolism and excretion of the dimethylaminoisopropanol and p-acetamidobenzoic acid components in rhesus monkeys.
Streeter DG; Pfadenhauer EH
Drug Metab Dispos; 1984; 12(2):199-203. PubMed ID: 6202473
[TBL] [Abstract][Full Text] [Related]
23. Lipophilic antifolates as agents against opportunistic infections. 1. Agents superior to trimetrexate and piritrexim against Toxoplasma gondii and Pneumocystis carinii in in vitro evaluations.
Piper JR; Johnson CA; Krauth CA; Carter RL; Hosmer CA; Queener SF; Borotz SE; Pfefferkorn ER
J Med Chem; 1996 Mar; 39(6):1271-80. PubMed ID: 8632434
[TBL] [Abstract][Full Text] [Related]
24. Crystal structure of the anti-bacterial sulfonamide drug target dihydropteroate synthase.
Achari A; Somers DO; Champness JN; Bryant PK; Rosemond J; Stammers DK
Nat Struct Biol; 1997 Jun; 4(6):490-7. PubMed ID: 9187658
[TBL] [Abstract][Full Text] [Related]
25. 2,4-Diamino-6,7-dihydro-5H-cyclopenta[d]pyrimidine analogues of trimethoprim as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase.
Rosowsky A; Papoulis AT; Queener SF
J Med Chem; 1998 Mar; 41(6):913-8. PubMed ID: 9526565
[TBL] [Abstract][Full Text] [Related]
26. Inhibitors of dihydropteroate synthase: substituent effects in the side-chain aromatic ring of 6-[[3-(aryloxy)propyl]amino]-5-nitrosoisocytosines and synthesis and inhibitory potency of bridged 5-nitrosoisocytosine-p-aminobenzoic acid analogues.
Lever OW; Bell LN; Hyman C; McGuire HM; Ferone R
J Med Chem; 1986 May; 29(5):665-70. PubMed ID: 3486292
[TBL] [Abstract][Full Text] [Related]
27. Pneumocystis carinii mutations associated with sulfa and sulfone prophylaxis failures in AIDS patients.
Kazanjian P; Locke AB; Hossler PA; Lane BR; Bartlett MS; Smith JW; Cannon M; Meshnick SR
AIDS; 1998 May; 12(8):873-8. PubMed ID: 9631140
[TBL] [Abstract][Full Text] [Related]
28. Pneumocystis carinii dihydropteroate synthase but not dihydrofolate reductase gene mutations correlate with prior trimethoprim-sulfamethoxazole or dapsone use.
Ma L; Borio L; Masur H; Kovacs JA
J Infect Dis; 1999 Dec; 180(6):1969-78. PubMed ID: 10558954
[TBL] [Abstract][Full Text] [Related]
29. Prevalence of dihydropteroate synthase mutants in HIV-infected South African children with Pneumocystis jiroveci pneumonia.
Zar HJ; Alvarez-Martinez MJ; Harrison A; Meshnick SR
Clin Infect Dis; 2004 Oct; 39(7):1047-51. PubMed ID: 15472859
[TBL] [Abstract][Full Text] [Related]
30. Novel dihydropteroate synthase gene mutation in Pneumocystis jirovecii among HIV-infected patients in India: Putative association with drug resistance and mortality.
Singh Y; Mirdha BR; Guleria R; Kabra SK; Mohan A; Chaudhry R; Kumar L; Dwivedi SN; Agarwal SK
J Glob Antimicrob Resist; 2019 Jun; 17():236-239. PubMed ID: 30658203
[TBL] [Abstract][Full Text] [Related]
31. Crystal structure of Mycobacterium tuberculosis 7,8-dihydropteroate synthase in complex with pterin monophosphate: new insight into the enzymatic mechanism and sulfa-drug action.
Baca AM; Sirawaraporn R; Turley S; Sirawaraporn W; Hol WG
J Mol Biol; 2000 Oct; 302(5):1193-212. PubMed ID: 11007651
[TBL] [Abstract][Full Text] [Related]
32. Clinical characteristics and prevalence of dihydropteroate synthase gene mutations in Pneumocystis jirovecii-infected AIDS patients from low endemic areas of China.
Zhu M; Ye N; Xu J
PLoS One; 2020; 15(9):e0238184. PubMed ID: 32911508
[TBL] [Abstract][Full Text] [Related]
33. High Prevalence of Pneumocystis jirovecii Dihydropteroate Synthase Gene Mutations in Patients with a First Episode of Pneumocystis Pneumonia in Santiago, Chile, and Clinical Response to Trimethoprim-Sulfamethoxazole Therapy.
Ponce CA; Chabé M; George C; Cárdenas A; Durán L; Guerrero J; Bustamante R; Matos O; Huang L; Miller RF; Vargas SL
Antimicrob Agents Chemother; 2017 Feb; 61(2):. PubMed ID: 27855071
[TBL] [Abstract][Full Text] [Related]
34. Dihydropteroate synthase (DHPS) gene mutation study in HIV-Infected Indian patients with Pneumocystis jirovecii pneumonia.
Tyagi AK; Mirdha BR; Luthra K; Guleria R; Mohan A; Singh UB; Samantaray JC; Dar L; Iyer VK; Chaudhry R
J Infect Dev Ctries; 2010 Nov; 4(11):761-6. PubMed ID: 21252456
[TBL] [Abstract][Full Text] [Related]
35. A radiometric method for objectively screening large numbers of compounds against Pneumocystis carinii in vitro.
Comley JC; Mullin RJ; Wolfe LA; Hanlon MH; Ferone R
J Protozool; 1991; 38(6):144S-146S. PubMed ID: 1818144
[TBL] [Abstract][Full Text] [Related]
36. 2,4-Diaminopyrido[3,2-d]pyrimidine inhibitors of dihydrofolate reductase from Pneumocystis carinii and Toxoplasma gondii.
Rosowsky A; Forsch RA; Queener SF
J Med Chem; 1995 Jul; 38(14):2615-20. PubMed ID: 7629801
[TBL] [Abstract][Full Text] [Related]
37. Epidemiology and clinical relevance of Pneumocystis jirovecii Frenkel, 1976 dihydropteroate synthase gene mutations.
Matos O; Esteves F
Parasite; 2010 Sep; 17(3):219-32. PubMed ID: 21073145
[TBL] [Abstract][Full Text] [Related]
38. Severity and outcome of HIV-associated Pneumocystis pneumonia containing Pneumocystis jirovecii dihydropteroate synthase gene mutations.
Crothers K; Beard CB; Turner J; Groner G; Fox M; Morris A; Eiser S; Huang L
AIDS; 2005 May; 19(8):801-5. PubMed ID: 15867494
[TBL] [Abstract][Full Text] [Related]
39. Pneumocystis jiroveci dihydropteroate synthase gene mutations among colonized individuals and Pneumocystis pneumonia patients from Spain.
Friaza V; Morilla R; Respaldiza N; de la Horra C; Calderón EJ
Postgrad Med; 2010 Nov; 122(6):24-8. PubMed ID: 21084778
[TBL] [Abstract][Full Text] [Related]
40. Genetic divergence of the dihydrofolate reductase and dihydropteroate synthase genes in Pneumocystis carinii from 7 different host species.
Ma L; Imamichi H; Sukura A; Kovacs JA
J Infect Dis; 2001 Nov; 184(10):1358-62. PubMed ID: 11679931
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]