These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

98 related articles for article (PubMed ID: 7695093)

  • 1. A microplate assay for trypanothione reductase inhibitors.
    Aumercier M; Meziane-Cherif D; Moutiez M; Tartar A; Sergheraert C
    Anal Biochem; 1994 Nov; 223(1):161-4. PubMed ID: 7695093
    [No Abstract]   [Full Text] [Related]  

  • 2. The synthesis and inhibitory activity of dethiotrypanothione and analogues against trypanothione reductase.
    Czechowicz JA; Wilhelm AK; Spalding MD; Larson AM; Engel LK; Alberg DG
    J Org Chem; 2007 May; 72(10):3689-93. PubMed ID: 17439174
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis of substrate analogues for trypanothione reductase.
    el-Waer AF; Benson T; Douglas KT
    Int J Pept Protein Res; 1993 Feb; 41(2):141-6. PubMed ID: 8458687
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibitors of trypanothione reductase as potential antitrypanosomal drugs.
    Chan C; Yin H; Garforth J; McKie JH; Jaouhari RA; Douglas KT; Fairlamb AH; Croft SL
    Biochem Soc Trans; 1995 Nov; 23(4):511S. PubMed ID: 8654696
    [No Abstract]   [Full Text] [Related]  

  • 5. Trypanothione and N1-glutathionylspermidine: isolation and determination.
    Krauth-Siegel RL; Jacoby EM; Schirmer RH
    Methods Enzymol; 1995; 251():287-94. PubMed ID: 7651207
    [No Abstract]   [Full Text] [Related]  

  • 6. Rationally designed selective inhibitors of trypanothione reductase. Phenothiazines and related tricyclics as lead structures.
    Benson TJ; McKie JH; Garforth J; Borges A; Fairlamb AH; Douglas KT
    Biochem J; 1992 Aug; 286 ( Pt 1)(Pt 1):9-11. PubMed ID: 1355650
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Molecular studies on trypanothione reductase, a target for antiparasitic drugs.
    Walsh C; Bradley M; Nadeau K
    Trends Biochem Sci; 1991 Aug; 16(8):305-9. PubMed ID: 1957352
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and evaluation of substrate analogue inhibitors of trypanothione reductase.
    Duyzend MH; Clark CT; Simmons SL; Johnson WB; Larson AM; Leconte AM; Wills AW; Ginder-Vogel M; Wilhelm AK; Czechowicz JA; Alberg DG
    J Enzyme Inhib Med Chem; 2012 Dec; 27(6):784-94. PubMed ID: 22085139
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ellman's-reagent-mediated regeneration of trypanothione in situ: substrate-economical microplate and time-dependent inhibition assays for trypanothione reductase.
    Hamilton CJ; Saravanamuthu A; Eggleston IM; Fairlamb AH
    Biochem J; 2003 Feb; 369(Pt 3):529-37. PubMed ID: 12416994
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Specific peptide inhibitors of trypanothione reductase with backbone structures unrelated to that of substrate: potential rational drug design lead frameworks.
    McKie JH; Garforth J; Jaouhari R; Chan C; Yin H; Besheya T; Fairlamb AH; Douglas KT
    Amino Acids; 2001; 20(2):145-53. PubMed ID: 11332449
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Trypanothione reductase from the human parasite Entamoeba histolytica: a new drug target.
    Tamayo EM; Iturbe A; Hernández E; Hurtado G; de Lourdes Gutiérrez-X M; Rosales JL; Woolery M; Ondarza RN
    Biotechnol Appl Biochem; 2005 Apr; 41(Pt 2):105-15. PubMed ID: 15157186
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The therapeutic potential of inhibitors of the trypanothione cycle.
    D'Silva C; Daunes S
    Expert Opin Investig Drugs; 2002 Feb; 11(2):217-31. PubMed ID: 11829713
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structural insights into the enzymes of the trypanothione pathway: targets for antileishmaniasis drugs.
    Colotti G; Baiocco P; Fiorillo A; Boffi A; Poser E; Chiaro FD; Ilari A
    Future Med Chem; 2013 Oct; 5(15):1861-75. PubMed ID: 24144416
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Trypanothione is the primary target for arsenical drugs against African trypanosomes.
    Fairlamb AH; Henderson GB; Cerami A
    Proc Natl Acad Sci U S A; 1989 Apr; 86(8):2607-11. PubMed ID: 2704738
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis and biological evaluation of new potent 5-nitrofuryl derivatives as anti-Trypanosoma cruzi agents. Studies of trypanothione binding site of trypanothione reductase as target for rational design.
    Aguirre G; Cabrera E; Cerecetto H; Di Maio R; González M; Seoane G; Duffaut A; Denicola A; Gil MJ; Martínez-Merino V
    Eur J Med Chem; 2004 May; 39(5):421-31. PubMed ID: 15110968
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Engineering the substrate specificity of glutathione reductase toward that of trypanothione reduction.
    Henderson GB; Murgolo NJ; Kuriyan J; Osapay K; Kominos D; Berry A; Scrutton NS; Hinchliffe NW; Perham RN; Cerami A
    Proc Natl Acad Sci U S A; 1991 Oct; 88(19):8769-73. PubMed ID: 1924337
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Redox enzyme engineering: conversion of human glutathione reductase into a trypanothione reductase.
    Bradley M; Bücheler US; Walsh CT
    Biochemistry; 1991 Jun; 30(25):6124-7. PubMed ID: 2059620
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Naegleria fowleri: a free-living highly pathogenic amoeba contains trypanothione/trypanothione reductase and glutathione/glutathione reductase systems.
    Ondarza RN; Hurtado G; Tamayo E; Iturbe A; Hernández E
    Exp Parasitol; 2006 Nov; 114(3):141-6. PubMed ID: 16620809
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Trypanothione: a novel bis(glutathionyl)spermidine cofactor for glutathione reductase in trypanosomatids.
    Fairlamb AH; Blackburn P; Ulrich P; Chait BT; Cerami A
    Science; 1985 Mar; 227(4693):1485-7. PubMed ID: 3883489
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The parasite-specific trypanothione metabolism of trypanosoma and leishmania.
    Krauth-Siegel RL; Meiering SK; Schmidt H
    Biol Chem; 2003 Apr; 384(4):539-49. PubMed ID: 12751784
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.