121 related articles for article (PubMed ID: 7697811)
1. Peroxidase activation of tamoxifen and toremifene resulting in DNA damage and covalently bound protein adducts.
Davies AM; Martin EA; Jones RM; Lim CK; Smith LL; White IN
Carcinogenesis; 1995 Mar; 16(3):539-45. PubMed ID: 7697811
[TBL] [Abstract][Full Text] [Related]
2. Comparisons of the binding of [14C]radiolabelled tamoxifen or toremifene to rat DNA using accelerator mass spectrometry.
White IN; Martin EA; Mauthe RJ; Vogel JS; Turteltaub KW; Smith LL
Chem Biol Interact; 1997 Sep; 106(2):149-60. PubMed ID: 9366900
[TBL] [Abstract][Full Text] [Related]
3. 4-Hydroxylated metabolites of the antiestrogens tamoxifen and toremifene are metabolized to unusually stable quinone methides.
Fan PW; Zhang F; Bolton JL
Chem Res Toxicol; 2000 Jan; 13(1):45-52. PubMed ID: 10649966
[TBL] [Abstract][Full Text] [Related]
4. DNA adducts caused by tamoxifen and toremifene in human microsomal system and lymphocytes in vitro.
Hemminki K; Widlak P; Hou SM
Carcinogenesis; 1995 Jul; 16(7):1661-4. PubMed ID: 7614704
[TBL] [Abstract][Full Text] [Related]
5. Further characterization of the DNA adducts formed in rat liver after the administration of tamoxifen, N-desmethyltamoxifen or N, N-didesmethyltamoxifen.
Brown K; Heydon RT; Jukes R; White IN; Martin EA
Carcinogenesis; 1999 Oct; 20(10):2011-6. PubMed ID: 10506118
[TBL] [Abstract][Full Text] [Related]
6. DNA adduct formation in the livers of female Sprague-Dawley rats treated with toremifene or alpha-hydroxytoremifene.
Gamboa da Costa G; Pereira PC; Churchwell MI; Beland FA; Marques MM
Chem Res Toxicol; 2007 Feb; 20(2):300-10. PubMed ID: 17261033
[TBL] [Abstract][Full Text] [Related]
7. Microsomal and peroxidase activation of 4-hydroxy-tamoxifen to form DNA adducts: comparison with DNA adducts formed in Sprague-Dawley rats treated with tamoxifen.
Pathak DN; Pongracz K; Bodell WJ
Carcinogenesis; 1995 Jan; 16(1):11-5. PubMed ID: 7834794
[TBL] [Abstract][Full Text] [Related]
8. Peroxidase-mediated dealkylation of tamoxifen, detected by electrospray ionization-mass spectrometry, and activation to form DNA adducts.
Gaikwad NW; Bodell WJ
Free Radic Biol Med; 2012 Jan; 52(2):340-7. PubMed ID: 22064363
[TBL] [Abstract][Full Text] [Related]
9. Genotoxic effects of the novel mixed antiestrogen FC-1271a in comparison to tamoxifen and toremifene.
Hellmann-Blumberg U; Taras TL; Wurz GT; DeGregorio MW
Breast Cancer Res Treat; 2000 Mar; 60(1):63-70. PubMed ID: 10845810
[TBL] [Abstract][Full Text] [Related]
10. Activation of the tamoxifen derivative metabolite E to form DNA adducts: comparison with the adducts formed by microsomal activation of tamoxifen.
Pongracz K; Pathak DN; Nakamura T; Burlingame AL; Bodell WJ
Cancer Res; 1995 Jul; 55(14):3012-5. PubMed ID: 7606720
[TBL] [Abstract][Full Text] [Related]
11. Mechanism of lower genotoxicity of toremifene compared with tamoxifen.
Shibutani S; Ravindernath A; Terashima I; Suzuki N; Laxmi YR; Kanno Y; Suzuki M; Apak TI; Sheng JJ; Duffel MW
Cancer Res; 2001 May; 61(10):3925-31. PubMed ID: 11358807
[TBL] [Abstract][Full Text] [Related]
12. Activation of 4-hydroxytamoxifen and the tamoxifen derivative metabolite E by uterine peroxidase to form DNA adducts: comparison with DNA adducts formed in the uterus of Sprague-Dawley rats treated with tamoxifen.
Pathak DN; Pongracz K; Bodell WJ
Carcinogenesis; 1996 Sep; 17(9):1785-90. PubMed ID: 8824496
[TBL] [Abstract][Full Text] [Related]
13. Lack of evidence for tamoxifen- and toremifene-DNA adducts in lymphocytes of treated patients.
Bartsch H; Phillips DH; Nair J; Hewer A; Meyberg-Solomeyer G; Grischke EM
Carcinogenesis; 2000 Apr; 21(4):845-7. PubMed ID: 10753226
[TBL] [Abstract][Full Text] [Related]
14. Intrinsic reactivity of tamoxifen and toremifene metabolites with DNA.
Hellmann-Blumberg U; Cartner MG; Wurz GT; DeGregorio MW
Breast Cancer Res Treat; 1998 Jul; 50(2):135-41. PubMed ID: 9822218
[TBL] [Abstract][Full Text] [Related]
15. Antiestrogenic and DNA damaging effects induced by tamoxifen and toremifene metabolites.
Liu X; Pisha E; Tonetti DA; Yao D; Li Y; Yao J; Burdette JE; Bolton JL
Chem Res Toxicol; 2003 Jul; 16(7):832-7. PubMed ID: 12870885
[TBL] [Abstract][Full Text] [Related]
16. DNA binding of tamoxifen and its analogues: identification of the tamoxifen-DNA adducts in rat liver.
Rajaniemi H; Koskinen M; Mäntylä E; Hemminki K
Toxicol Lett; 1998 Dec; 102-103():453-7. PubMed ID: 10022295
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and reactivity of potential toxic metabolites of tamoxifen analogues: droloxifene and toremifene o-quinones.
Yao D; Zhang F; Yu L; Yang Y; van Breemen RB; Bolton JL
Chem Res Toxicol; 2001 Dec; 14(12):1643-53. PubMed ID: 11743747
[TBL] [Abstract][Full Text] [Related]
18. Characterization of the biotransformation pathways of clomiphene, tamoxifen and toremifene as assessed by LC-MS/(MS) following in vitro and excretion studies.
Mazzarino M; Biava M; de la Torre X; Fiacco I; Botrè F
Anal Bioanal Chem; 2013 Jun; 405(16):5467-87. PubMed ID: 23604525
[TBL] [Abstract][Full Text] [Related]
19. Genotoxicity of tamoxifen, tamoxifen epoxide and toremifene in human lymphoblastoid cells containing human cytochrome P450s.
Styles JA; Davies A; Lim CK; De Matteis F; Stanley LA; White IN; Yuan ZX; Smith LL
Carcinogenesis; 1994 Jan; 15(1):5-9. PubMed ID: 8293548
[TBL] [Abstract][Full Text] [Related]
20. DNA cleavage and 8-hydroxydeoxyguanosine formation caused by tamoxifen derivatives in vitro.
Okubo T; Nagai F; Ushiyama K; Yokoyama Y; Ozawa S; Kano K; Tomita S; Kubo H; Kano I
Cancer Lett; 1998 Jan; 122(1-2):9-15. PubMed ID: 9464485
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
