159 related articles for article (PubMed ID: 7700866)
1. Comparison of the construction of a 3-D model for human thromboxane synthase using P450cam and BM-3 as templates: implications for the substrate binding pocket.
Ruan KH; Milfeld K; Kulmacz RJ; Wu KK
Protein Eng; 1994 Nov; 7(11):1345-51. PubMed ID: 7700866
[TBL] [Abstract][Full Text] [Related]
2. Identification of thromboxane A2 synthase active site residues by molecular modeling-guided site-directed mutagenesis.
Wang LH; Matijevic-Aleksic N; Hsu PY; Ruan KH; Wu KK; Kulmacz RJ
J Biol Chem; 1996 Aug; 271(33):19970-5. PubMed ID: 8702713
[TBL] [Abstract][Full Text] [Related]
3. Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's.
Ravichandran KG; Boddupalli SS; Hasermann CA; Peterson JA; Deisenhofer J
Science; 1993 Aug; 261(5122):731-6. PubMed ID: 8342039
[TBL] [Abstract][Full Text] [Related]
4. How do substrates enter and products exit the buried active site of cytochrome P450cam? 1. Random expulsion molecular dynamics investigation of ligand access channels and mechanisms.
Lüdemann SK; Lounnas V; Wade RC
J Mol Biol; 2000 Nov; 303(5):797-811. PubMed ID: 11061976
[TBL] [Abstract][Full Text] [Related]
5. The structure of the cytochrome p450BM-3 haem domain complexed with the fatty acid substrate, palmitoleic acid.
Li H; Poulos TL
Nat Struct Biol; 1997 Feb; 4(2):140-6. PubMed ID: 9033595
[TBL] [Abstract][Full Text] [Related]
6. Active site topologies of bacterial cytochromes P450101 (P450cam), P450108 (P450terp), and P450102 (P450BM-3). In situ rearrangement of their phenyl-iron complexes.
Tuck SF; Peterson JA; Ortiz de Montellano PR
J Biol Chem; 1992 Mar; 267(8):5614-20. PubMed ID: 1544935
[TBL] [Abstract][Full Text] [Related]
7. Conformational dynamics in cytochrome P450-substrate interactions.
Li H; Poulos TL
Biochimie; 1996; 78(8-9):695-9. PubMed ID: 9010597
[TBL] [Abstract][Full Text] [Related]
8. A three-dimensional model of aromatase cytochrome P450.
Graham-Lorence S; Amarneh B; White RE; Peterson JA; Simpson ER
Protein Sci; 1995 Jun; 4(6):1065-80. PubMed ID: 7549871
[TBL] [Abstract][Full Text] [Related]
9. Homology modelling of the enzyme P450 17 alpha-hydroxylase/17,20-lyase--a target for prostate cancer chemotherapy--from the crystal structure of P450BM-3.
Burke DF; Laughton CA; Neidle S
Anticancer Drug Des; 1997 Mar; 12(2):113-23. PubMed ID: 9113066
[TBL] [Abstract][Full Text] [Related]
10. Substrate binding is the rate-limiting step in thromboxane synthase catalysis.
Wang LH; Tsai AL; Hsu PY
J Biol Chem; 2001 May; 276(18):14737-43. PubMed ID: 11297515
[TBL] [Abstract][Full Text] [Related]
11. Reaction of carbon monoxide and molecular oxygen with P450terp (CYP108) and P450BM-3 (CYP102).
Sevrioukova IF; Peterson JA
Arch Biochem Biophys; 1995 Mar; 317(2):397-404. PubMed ID: 7893155
[TBL] [Abstract][Full Text] [Related]
12. The domain architecture of cytochrome P450BM-3.
Govindaraj S; Poulos TL
J Biol Chem; 1997 Mar; 272(12):7915-21. PubMed ID: 9065459
[TBL] [Abstract][Full Text] [Related]
13. A predicted three-dimensional structure of human cytochrome P450: implications for substrate specificity.
Zvelebil MJ; Wolf CR; Sternberg MJ
Protein Eng; 1991 Feb; 4(3):271-82. PubMed ID: 1857713
[TBL] [Abstract][Full Text] [Related]
14. Biotransformation of the sesquiterpene (+)-valencene by cytochrome P450cam and P450BM-3.
Sowden RJ; Yasmin S; Rees NH; Bell SG; Wong LL
Org Biomol Chem; 2005 Jan; 3(1):57-64. PubMed ID: 15602599
[TBL] [Abstract][Full Text] [Related]
15. Construction and evaluation of a three-dimensional structure of cytochrome P450choP enzyme (CYP105C1).
Chang YT; Loew GH
Protein Eng; 1996 Sep; 9(9):755-66. PubMed ID: 8888141
[TBL] [Abstract][Full Text] [Related]
16. Protein engineering of thromboxane synthase: conversion of membrane-bound to soluble form.
Hsu PY; Wang LH
Arch Biochem Biophys; 2003 Aug; 416(1):38-46. PubMed ID: 12859980
[TBL] [Abstract][Full Text] [Related]
17. Interactions of substrates at the surface of P450s can greatly enhance substrate potency.
Hegde A; Haines DC; Bondlela M; Chen B; Schaffer N; Tomchick DR; Machius M; Nguyen H; Chowdhary PK; Stewart L; Lopez C; Peterson JA
Biochemistry; 2007 Dec; 46(49):14010-7. PubMed ID: 18004886
[TBL] [Abstract][Full Text] [Related]
18. Role of the linker region connecting the reductase and heme domains in cytochrome P450BM-3.
Govindaraj S; Poulos TL
Biochemistry; 1995 Sep; 34(35):11221-6. PubMed ID: 7669780
[TBL] [Abstract][Full Text] [Related]
19. Oxygen activation by cytochrome P450BM-3: effects of mutating an active site acidic residue.
Yeom H; Sligar SG
Arch Biochem Biophys; 1997 Jan; 337(2):209-16. PubMed ID: 9016815
[TBL] [Abstract][Full Text] [Related]
20. Crystal structure of inhibitor-bound P450BM-3 reveals open conformation of substrate access channel.
Haines DC; Chen B; Tomchick DR; Bondlela M; Hegde A; Machius M; Peterson JA
Biochemistry; 2008 Mar; 47(12):3662-70. PubMed ID: 18298086
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
