BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

223 related articles for article (PubMed ID: 7702642)

  • 1. Different analogues of farnesyl pyrophosphate inhibit squalene synthase and protein:farnesyltransferase to different extents.
    Cohen LH; Valentijn AR; Roodenburg L; Van Leeuwen RE; Huisman RH; Lutz RJ; Van der Marel GA; Van Boom JH
    Biochem Pharmacol; 1995 Mar; 49(6):839-45. PubMed ID: 7702642
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of human smooth muscle cell proliferation in culture by farnesyl pyrophosphate analogues, inhibitors of in vitro protein: farnesyl transferase.
    Cohen LH; Pieterman E; van Leeuwen RE; Du J; Negre-Aminou P; Valentijn AR; Overhand M; van der Marel GA; van Boom JH
    Biochem Pharmacol; 1999 Feb; 57(4):365-73. PubMed ID: 9933024
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein farnesyltransferase: measurement of enzymatic activity in 96-well format using TopCount microplate scintillation counting technology.
    Harwood HJ
    Anal Biochem; 1995 Apr; 226(2):268-78. PubMed ID: 7793628
    [TBL] [Abstract][Full Text] [Related]  

  • 4. J-104,871, a novel farnesyltransferase inhibitor, blocks Ras farnesylation in vivo in a farnesyl pyrophosphate-competitive manner.
    Yonemoto M; Satoh T; Arakawa H; Suzuki-Takahashi I; Monden Y; Kodera T; Tanaka K; Aoyama T; Iwasawa Y; Kamei T; Nishimura S; Tomimoto K
    Mol Pharmacol; 1998 Jul; 54(1):1-7. PubMed ID: 9658183
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibition of farnesyltransferase with A-176120, a novel and potent farnesyl pyrophosphate analogue.
    Tahir SK; Gu WZ; Zhang HC; Leal J; Lee JY; Kovar P; Saeed B; Cherian SP; Devine E; Cohen J; Warner R; Wang YC; Stout D; Arendsen DL; Rosenberg S; Ng SC
    Eur J Cancer; 2000 Jun; 36(9):1161-70. PubMed ID: 10854950
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Farnesylation of p21 Ras proteins in Xenopus oocytes.
    Zhao J; Kung HF; Manne V
    Cell Mol Biol Res; 1994; 40(4):313-21. PubMed ID: 7866432
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of farnesyl transferases from malignant and non-malignant cultured human lymphocytes by prenyl substrate analogues.
    Das NP; Allen CM
    Biochem Biophys Res Commun; 1991 Dec; 181(2):729-35. PubMed ID: 1755854
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Stereochemistry-dependent inhibition of RAS farnesylation by farnesyl phosphonic acids.
    Hohl RJ; Lewis KA; Cermak DM; Wiemer DF
    Lipids; 1998 Jan; 33(1):39-46. PubMed ID: 9470172
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Design and synthesis of a transferable farnesyl pyrophosphate analogue to Ras by protein farnesyltransferase.
    Chehade KA; Andres DA; Morimoto H; Spielmann HP
    J Org Chem; 2000 May; 65(10):3027-33. PubMed ID: 10814193
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Hydrophilic anilinogeranyl diphosphate prenyl analogues are Ras function inhibitors.
    Roberts MJ; Troutman JM; Chehade KA; Cha HC; Kao JP; Huang X; Zhan CG; Peterson YK; Subramanian T; Kamalakkannan S; Andres DA; Spielmann HP
    Biochemistry; 2006 Dec; 45(51):15862-72. PubMed ID: 17176109
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Farnesyl diphosphate-based inhibitors of Ras farnesyl protein transferase.
    Patel DV; Schmidt RJ; Biller SA; Gordon EM; Robinson SS; Manne V
    J Med Chem; 1995 Jul; 38(15):2906-21. PubMed ID: 7636851
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Farnesyl-derived inhibitors of ras farnesyl transferase.
    Kang MS; Stemerick DM; Zwolshen JH; Harry BS; Sunkara PS; Harrison BL
    Biochem Biophys Res Commun; 1995 Dec; 217(1):245-9. PubMed ID: 8526918
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Zaragozic acids D and D2: potent inhibitors of squalene synthase and of Ras farnesyl-protein transferase.
    Dufresne C; Wilson KE; Singh SB; Zink DL; Bergstrom JD; Rew D; Polishook JD; Meinz M; Huang L; Silverman KC
    J Nat Prod; 1993 Nov; 56(11):1923-9. PubMed ID: 8289063
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Polyisoprenylation of Ras in vitro by a farnesyl-protein transferase.
    Schaber MD; O'Hara MB; Garsky VM; Mosser SC; Bergstrom JD; Moores SL; Marshall MS; Friedman PA; Dixon RA; Gibbs JB
    J Biol Chem; 1990 Sep; 265(25):14701-4. PubMed ID: 2203759
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Clavaric acid and steroidal analogues as Ras- and FPP-directed inhibitors of human farnesyl-protein transferase.
    Lingham RB; Silverman KC; Jayasuriya H; Kim BM; Amo SE; Wilson FR; Rew DJ; Schaber MD; Bergstrom JD; Koblan KS; Graham SL; Kohl NE; Gibbs JB; Singh SB
    J Med Chem; 1998 Nov; 41(23):4492-501. PubMed ID: 9804689
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Nonidentical subunits of p21H-ras farnesyltransferase. Peptide binding and farnesyl pyrophosphate carrier functions.
    Reiss Y; Seabra MC; Armstrong SA; Slaughter CA; Goldstein JL; Brown MS
    J Biol Chem; 1991 Jun; 266(16):10672-7. PubMed ID: 2037606
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Isoprenoid (phosphinylmethyl)phosphonates as inhibitors of squalene synthetase.
    Biller SA; Forster C; Gordon EM; Harrity T; Scott WA; Ciosek CP
    J Med Chem; 1988 Oct; 31(10):1869-71. PubMed ID: 3172121
    [No Abstract]   [Full Text] [Related]  

  • 18. Phosphonate and bisphosphonate analogues of farnesyl pyrophosphate as potential inhibitors of farnesyl protein transferase.
    Holstein SA; Cermak DM; Wiemer DF; Lewis K; Hohl RJ
    Bioorg Med Chem; 1998 Jun; 6(6):687-94. PubMed ID: 9681134
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of purified p21ras farnesyl:protein transferase by Cys-AAX tetrapeptides.
    Reiss Y; Goldstein JL; Seabra MC; Casey PJ; Brown MS
    Cell; 1990 Jul; 62(1):81-8. PubMed ID: 2194674
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A rapid and convenient filter-binding assay for ras p21 processing enzyme farnesyltransferase.
    Khan SG; Mukhtar H; Agarwal R
    J Biochem Biophys Methods; 1995 Jun; 30(2-3):133-44. PubMed ID: 7494090
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.