212 related articles for article (PubMed ID: 7703351)
1. Inhibition of bovine beta-trypsin, human alpha-thrombin and porcine pancreatic beta-kallikrein-B by 4',6-diamidino-2-phenylindole, 6-amidinoindole and benzamidine: a comparative thermodynamic and X-ray structural study.
Casale E; Collyer C; Ascenzi P; Balliano G; Milla P; Viola F; Fasano M; Menegatti E; Bolognesi M
Biophys Chem; 1995 Mar; 54(1):75-81. PubMed ID: 7703351
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of bovine beta-trypsin, human alpha-thrombin and porcine pancreatic beta-kallikrein-B by benzamidine and its bis-, tris- and tetra-derivatives: thermodynamic and molecular modeling study.
Menegatti E; Ferroni R; Nastruzzi C; Bortolotti F; Scalia S; Amiconi G; Bolognesi M; Coletta M; Onesti S; Fruttero R
Farmaco; 1991 Nov; 46(11):1297-310. PubMed ID: 1811616
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of human alpha-, beta- and gamma-thrombin by mono-, bis-, tris- and tetra-benzamidine structures: thermodynamic study.
Ascenzi P; Fruttero R; Amiconi G; Pugliese L; Bolognesi M; Coletta M; Onesti S; Guarneri M; Menegatti E
J Enzyme Inhib; 1992; 6(2):131-9. PubMed ID: 1284429
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of serine proteinases by tetra-p-amidinophenoxy-neo-pentane: thermodynamic and molecular modeling study.
Menegatti E; Ferroni R; Scalia S; Guarneri M; Bolognesi M; Ascenzi P; Amiconi G
J Enzyme Inhib; 1987; 2(1):23-30. PubMed ID: 3508169
[TBL] [Abstract][Full Text] [Related]
5. Comparative molecular modeling analysis of-5-amidinoindole and benzamidine binding to thrombin and trypsin: specific H-bond formation contributes to high 5-amidinoindole potency and selectivity for thrombin and factor Xa.
Zhou Y; Johnson ME
J Mol Recognit; 1999; 12(4):235-41. PubMed ID: 10440994
[TBL] [Abstract][Full Text] [Related]
6. Human alpha-thrombin inhibition by the active site titrant N alpha-(N,N-dimethylcarbamoyl)-alpha-azalysine p-nitrophenyl ester: a comparative kinetic and X-ray crystallographic study.
Nardini M; Pesce A; Rizzi M; Casale E; Ferraccioli R; Balliano G; Milla P; Ascenzi P; Bolognesi M
J Mol Biol; 1996 May; 258(5):851-9. PubMed ID: 8637015
[TBL] [Abstract][Full Text] [Related]
7. Inhibition of serine proteinases by p-carbethoxyphenyl esters of epsilon-guanidino- and epsilon-amino caproic acid: thermodynamic and molecular modeling study.
Menegatti E; Guaneri M; Bolognesi M; Ascenzi P; Amiconi G
J Enzyme Inhib; 1989; 2(4):249-59. PubMed ID: 2723772
[TBL] [Abstract][Full Text] [Related]
8. Binding of native and [homoserine lactone-52]-52,53-seco-bovine basic pancreatic trypsin inhibitor (Kunitz inhibitor) to porcine pancreatic beta-kallikrein-B and bovine alpha-chymotrypsin: thermodynamic study.
Oddone R; Barra D; Amiconi G; Ascenzi P; Tarricone C; Bolognesi M; Bortolotti F; Menegatti E
J Mol Recognit; 1994 Mar; 7(1):39-46. PubMed ID: 7527234
[TBL] [Abstract][Full Text] [Related]
9. Ethyl esters of N-(3- and N-(4-amidinobenzoyl)(-L-)amino acids: synthesis and antiproteolytic activity towards bovine trypsin and porcine pancreatic kallikrein.
Ferroni R; Menegatti E; Orlandini P; Scalia S; Guarneri M; Bolognesi M; Ascenzi P
Farmaco Sci; 1985 Oct; 40(10):717-29. PubMed ID: 3853512
[TBL] [Abstract][Full Text] [Related]
10. Structural and functional analyses of benzamidine-based inhibitors in complex with trypsin: implications for the inhibition of factor Xa, tPA, and urokinase.
Renatus M; Bode W; Huber R; Stürzebecher J; Stubbs MT
J Med Chem; 1998 Dec; 41(27):5445-56. PubMed ID: 9876114
[TBL] [Abstract][Full Text] [Related]
11. A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site.
Katz BA; Elrod K; Luong C; Rice MJ; Mackman RL; Sprengeler PA; Spencer J; Hataye J; Janc J; Link J; Litvak J; Rai R; Rice K; Sideris S; Verner E; Young W
J Mol Biol; 2001 Apr; 307(5):1451-86. PubMed ID: 11292354
[TBL] [Abstract][Full Text] [Related]
12. Comparison of the structures of the cyclotheonamide A complexes of human alpha-thrombin and bovine beta-trypsin.
Ganesh V; Lee AY; Clardy J; Tulinsky A
Protein Sci; 1996 May; 5(5):825-35. PubMed ID: 8732754
[TBL] [Abstract][Full Text] [Related]
13. Molecular design and characterization of an alpha-thrombin inhibitor containing a novel P1 moiety.
Malikayil JA; Burkhart JP; Schreuder HA; Broersma RJ; Tardif C; Kutcher LW; Mehdi S; Schatzman GL; Neises B; Peet NP
Biochemistry; 1997 Feb; 36(5):1034-40. PubMed ID: 9033393
[TBL] [Abstract][Full Text] [Related]
14. Active site mapping of trypsin, thrombin and matriptase-2 by sulfamoyl benzamidines.
Dosa S; Stirnberg M; Lülsdorff V; Häußler D; Maurer E; Gütschow M
Bioorg Med Chem; 2012 Nov; 20(21):6489-505. PubMed ID: 23026080
[TBL] [Abstract][Full Text] [Related]
15. Oxyanion-mediated inhibition of serine proteases.
Presnell SR; Patil GS; Mura C; Jude KM; Conley JM; Bertrand JA; Kam CM; Powers JC; Williams LD
Biochemistry; 1998 Dec; 37(48):17068-81. PubMed ID: 9836602
[TBL] [Abstract][Full Text] [Related]
16. Inhibition of serine proteinases by squash inhibitors.
Otlewski J; Zbyryt T; Krokoszyńska I; Wilusz T
Biol Chem Hoppe Seyler; 1990 Jul; 371(7):589-94. PubMed ID: 2145863
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of glandular and plasma kallikrein by benzamidine derivatives.
Stürzebecher J; Vieweg H; Prasa D
Agents Actions Suppl; 1992; 38 ( Pt 1)():190-7. PubMed ID: 1466270
[TBL] [Abstract][Full Text] [Related]
18. Elaborate manifold of short hydrogen bond arrays mediating binding of active site-directed serine protease inhibitors.
Katz BA; Elrod K; Verner E; Mackman RL; Luong C; Shrader WD; Sendzik M; Spencer JR; Sprengeler PA; Kolesnikov A; Tai VW; Hui HC; Breitenbucher JG; Allen D; Janc JW
J Mol Biol; 2003 May; 329(1):93-120. PubMed ID: 12742021
[TBL] [Abstract][Full Text] [Related]
19. Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics.
Brandstetter H; Turk D; Hoeffken HW; Grosse D; Stürzebecher J; Martin PD; Edwards BF; Bode W
J Mol Biol; 1992 Aug; 226(4):1085-99. PubMed ID: 1518046
[TBL] [Abstract][Full Text] [Related]
20. Novel bis(benzamidino) compounds with an aromatic central link. Inhibitors of thrombin, pancreatic kallikrein, trypsin, and complement.
Geratz JD; Cheng MC; Tidwell RR
J Med Chem; 1976 May; 19(5):634-9. PubMed ID: 1271404
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
