These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 7703859)

  • 1. A structural comparison of 21 inhibitor complexes of the aspartic proteinase from Endothia parasitica.
    Bailey D; Cooper JB
    Protein Sci; 1994 Nov; 3(11):2129-43. PubMed ID: 7703859
    [TBL] [Abstract][Full Text] [Related]  

  • 2. X-ray analyses of aspartic proteinases. III Three-dimensional structure of endothiapepsin complexed with a transition-state isostere inhibitor of renin at 1.6 A resolution.
    Veerapandian B; Cooper JB; Sali A; Blundell TL
    J Mol Biol; 1990 Dec; 216(4):1017-29. PubMed ID: 2266553
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution.
    Tsunemi M; Matsuura Y; Sakakibara S; Katsube Y
    Biochemistry; 1996 Sep; 35(36):11570-6. PubMed ID: 8794736
    [TBL] [Abstract][Full Text] [Related]  

  • 4. X-ray structures of five renin inhibitors bound to saccharopepsin: exploration of active-site specificity.
    Cronin NB; Badasso MO; J Tickle I; Dreyer T; Hoover DJ; Rosati RL; Humblet CC; Lunney EA; Cooper JB
    J Mol Biol; 2000 Nov; 303(5):745-60. PubMed ID: 11061973
    [TBL] [Abstract][Full Text] [Related]  

  • 5. X-ray analyses of aspartic proteinases. V. Structure and refinement at 2.0 A resolution of the aspartic proteinase from Mucor pusillus.
    Newman M; Watson F; Roychowdhury P; Jones H; Badasso M; Cleasby A; Wood SP; Tickle IJ; Blundell TL
    J Mol Biol; 1993 Mar; 230(1):260-83. PubMed ID: 8450540
    [TBL] [Abstract][Full Text] [Related]  

  • 6. X-ray-crystallographic studies of complexes of pepstatin A and a statine-containing human renin inhibitor with endothiapepsin.
    Bailey D; Cooper JB; Veerapandian B; Blundell TL; Atrash B; Jones DM; Szelke M
    Biochem J; 1993 Jan; 289 ( Pt 2)(Pt 2):363-71. PubMed ID: 8424781
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Variability of the canonical loop conformations in serine proteinases inhibitors and other proteins.
    Apostoluk W; Otlewski J
    Proteins; 1998 Sep; 32(4):459-74. PubMed ID: 9726416
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Three-dimensional structures of HIV-1 and SIV protease product complexes.
    Rose RB; Craik CS; Douglas NL; Stroud RM
    Biochemistry; 1996 Oct; 35(39):12933-44. PubMed ID: 8841139
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition and catalytic mechanism of HIV-1 aspartic protease.
    Silva AM; Cachau RE; Sham HL; Erickson JW
    J Mol Biol; 1996 Jan; 255(2):321-46. PubMed ID: 8551523
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A novel serine protease inhibition motif involving a multi-centered short hydrogen bonding network at the active site.
    Katz BA; Elrod K; Luong C; Rice MJ; Mackman RL; Sprengeler PA; Spencer J; Hataye J; Janc J; Link J; Litvak J; Rai R; Rice K; Sideris S; Verner E; Young W
    J Mol Biol; 2001 Apr; 307(5):1451-86. PubMed ID: 11292354
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Thermodynamic mapping of the inhibitor site of the aspartic protease endothiapepsin.
    Gómez J; Freire E
    J Mol Biol; 1995 Sep; 252(3):337-50. PubMed ID: 7563055
    [TBL] [Abstract][Full Text] [Related]  

  • 12. X-ray studies of aspartic proteinase-statine inhibitor complexes.
    Cooper JB; Foundling SI; Blundell TL; Boger J; Jupp RA; Kay J
    Biochemistry; 1989 Oct; 28(21):8596-603. PubMed ID: 2690945
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Domain flexibility in aspartic proteinases.
    Sali A; Veerapandian B; Cooper JB; Moss DS; Hofmann T; Blundell TL
    Proteins; 1992 Feb; 12(2):158-70. PubMed ID: 1603805
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Contribution of peptide bonds to inhibitor-protease binding: crystal structures of the turkey ovomucoid third domain backbone variants OMTKY3-Pro18I and OMTKY3-psi[COO]-Leu18I in complex with Streptomyces griseus proteinase B (SGPB) and the structure of the free inhibitor, OMTKY-3-psi[CH2NH2+]-Asp19I.
    Bateman KS; Huang K; Anderson S; Lu W; Qasim MA; Laskowski M; James MN
    J Mol Biol; 2001 Jan; 305(4):839-49. PubMed ID: 11162096
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Five atomic resolution structures of endothiapepsin inhibitor complexes: implications for the aspartic proteinase mechanism.
    Coates L; Erskine PT; Crump MP; Wood SP; Cooper JB
    J Mol Biol; 2002 May; 318(5):1405-15. PubMed ID: 12083527
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Direct observation by X-ray analysis of the tetrahedral "intermediate" of aspartic proteinases.
    Veerapandian B; Cooper JB; Sali A; Blundell TL; Rosati RL; Dominy BW; Damon DB; Hoover DJ
    Protein Sci; 1992 Mar; 1(3):322-8. PubMed ID: 1304340
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Thermodynamic criterion for the conformation of P1 residues of substrates and of inhibitors in complexes with serine proteinases.
    Qasim MA; Lu SM; Ding J; Bateman KS; James MN; Anderson S; Song J; Markley JL; Ganz PJ; Saunders CW; Laskowski M
    Biochemistry; 1999 Jun; 38(22):7142-50. PubMed ID: 10353824
    [TBL] [Abstract][Full Text] [Related]  

  • 18. High resolution X-ray analyses of renin inhibitor-aspartic proteinase complexes.
    Foundling SI; Cooper J; Watson FE; Cleasby A; Pearl LH; Sibanda BL; Hemmings A; Wood SP; Blundell TL; Valler MJ
    Nature; 1987 May 28-Jun 3; 327(6120):349-52. PubMed ID: 3295561
    [TBL] [Abstract][Full Text] [Related]  

  • 19. X-ray analyses of aspartic proteinases. II. Three-dimensional structure of the hexagonal crystal form of porcine pepsin at 2.3 A resolution.
    Cooper JB; Khan G; Taylor G; Tickle IJ; Blundell TL
    J Mol Biol; 1990 Jul; 214(1):199-222. PubMed ID: 2115088
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Flap position of free memapsin 2 (beta-secretase), a model for flap opening in aspartic protease catalysis.
    Hong L; Tang J
    Biochemistry; 2004 Apr; 43(16):4689-95. PubMed ID: 15096037
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.