BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

244 related articles for article (PubMed ID: 7707319)

  • 1. Synthesis and in vitro activity of 17 beta-(N-alkyl/arylformamido)- and 17 beta-[(N-alkyl/aryl)alkyl/arylamido]-4-methyl-4-aza-3-oxo-5 alpha-androstan-3-ones as inhibitors of human 5 alpha-reductases and antagonists of the androgen receptor.
    Li X; Singh SM; Labrie F
    J Med Chem; 1995 Mar; 38(7):1158-73. PubMed ID: 7707319
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activity of 17beta-(N-alkyl/arylformamido) and 17beta-[(N-alkyl/aryl) alkyl/arylamido]-4-methyl-4-aza-5alpha-androstan-3-ones as 5alpha-reductase inhibitors in the hamster flank organ and ear.
    Chen C; Li X; Singh SM; Labrie F
    J Invest Dermatol; 1998 Aug; 111(2):273-8. PubMed ID: 9699729
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and in vitro study of 17 beta-[N-ureylene-N,N'-disubstituted]-4-methyl-4-aza-5 alpha-androstan-3-ones as selective inhibitors of type I 5 alpha-reductase.
    Lourdusamy M; Côté J; Laplante S; Labrie F; Singh SM
    Bioorg Med Chem; 1997 Feb; 5(2):305-10. PubMed ID: 9061195
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 4-Methyl-3-oxo-4-aza-5alpha-androst-1-ene-17beta-N-aryl-carboxamides: an approach to combined androgen blockade [5alpha-reductase inhibition with androgen receptor binding in vitro].
    Tolman RL; Sahoo SP; Bakshi RK; Gratale D; Patel G; Patel S; Toney J; Chang B; Harris GS
    J Steroid Biochem Mol Biol; 1997 Mar; 60(5-6):303-9. PubMed ID: 9219921
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Azasteroids as inhibitors of testosterone 5 alpha-reductase in mammalian skin.
    Mellin TN; Busch RD; Rasmusson GH
    J Steroid Biochem Mol Biol; 1993 Feb; 44(2):121-31. PubMed ID: 8439517
    [TBL] [Abstract][Full Text] [Related]  

  • 6. 5 Alpha-reductase inhibitory and anti-androgenic activities of some 4-azasteroids in the rat.
    Brooks JR; Berman C; Primka RL; Reynolds GF; Rasmusson GH
    Steroids; 1986 Jan; 47(1):1-19. PubMed ID: 3810695
    [TBL] [Abstract][Full Text] [Related]  

  • 7. 4-Azasteroidal 5 alpha-reductase inhibitors without affinity for the androgen receptor.
    Liang T; Heiss CE; Cheung AH; Reynolds GF; Rasmusson GH
    J Biol Chem; 1984 Jan; 259(2):734-9. PubMed ID: 6693392
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The effects of diethyl-4-methyl-3-oxo-4-aza-5 alpha-androstane-17 beta-carboxamide (4-MA) and (4R)-5,10-SECO-19-norpregna-4,5-diene-3,10,20-trione (SECO) on androgen biosynthesis in the rat testis and epididymis.
    Cooke GM; Robaire B
    J Steroid Biochem; 1986 Apr; 24(4):877-86. PubMed ID: 3702462
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and in vitro evaluation of 4-substituted N-(1,1-dimethylethyl)-3-oxo-4-androstene-17 beta-carboxamides as 5 alpha-reductase inhibitors and antiandrogens.
    Li X; Singh SM; Côté J; Laplante S; Veilleux R; Labrie F
    J Med Chem; 1995 Apr; 38(9):1456-61. PubMed ID: 7739004
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 17 beta-acylurea derivatives of 4-azasteroids as inhibitors of testosterone 5 alpha-reductase.
    Di Salle E; Briatico G; Giudici D; Ornati G; Nesi M; Panzeri A
    J Steroid Biochem Mol Biol; 1992 Mar; 41(3-8):765-8. PubMed ID: 1373305
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Azasteroids as inhibitors of rat prostatic 5 alpha-reductase.
    Rasmusson GH; Reynolds GF; Utne T; Jobson RB; Primka RL; Berman C; Brooks JR
    J Med Chem; 1984 Dec; 27(12):1690-701. PubMed ID: 6502599
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Azasteroids: structure-activity relationships for inhibition of 5 alpha-reductase and of androgen receptor binding.
    Rasmusson GH; Reynolds GF; Steinberg NG; Walton E; Patel GF; Liang T; Cascieri MA; Cheung AH; Brooks JR; Berman C
    J Med Chem; 1986 Nov; 29(11):2298-315. PubMed ID: 3783591
    [TBL] [Abstract][Full Text] [Related]  

  • 13. 12. Androgens: Pharmacodynamics and antagonists. Biochemical and biological studies with 4-aza-steroidal 5 alpha-reductase inhibitors.
    Liang T; Rasmusson GH; Brooks JR
    J Steroid Biochem; 1983 Jul; 19(1A):385-90. PubMed ID: 6887871
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of steroid 5 alpha-reductase and its effects on testosterone hydroxylation by rat liver microsomal cytochrome P-450.
    Sonderfan AJ; Parkinson A
    Arch Biochem Biophys; 1988 Aug; 265(1):208-18. PubMed ID: 3415243
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The inhibition of 3 beta HSD activity in porcine granulosa cells by 4-MA, a potent 5 alpha-reductase inhibitor.
    Chan WK; Fong CY; Tiong HH; Tan CH
    Biochem Biophys Res Commun; 1987 Apr; 144(1):166-71. PubMed ID: 3107552
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Growth inhibition of human prostate cells in vitro by novel inhibitors of androgen synthesis.
    Klus GT; Nakamura J; Li JS; Ling YZ; Son C; Kemppainen JA; Wilson EM; Brodie AM
    Cancer Res; 1996 Nov; 56(21):4956-64. PubMed ID: 8895750
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Effects of 4-MA, a potent inhibitor of 5 alpha-reductase, on 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase activity in guinea pig adrenals.
    Perron S; Bélanger A
    Steroids; 1994 Jun; 59(6):371-6. PubMed ID: 7940615
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of 5 alpha-reductase activity and alteration of nuclear testosterone. Dihydrotestosterone ratio in human genital skin fibroblasts.
    Berkovitz GD; Brown TR; Migeon CJ
    J Androl; 1984; 5(3):171-5. PubMed ID: 6746410
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The effects of N,N-diethyl-4-methyl-3-oxo-4-aza-5 alpha-androstane-17 beta-carboxamide, a 5 alpha-reductase inhibitor and antiandrogen, on the development of baldness in the stumptail macaque.
    Rittmaster RS; Uno H; Povar ML; Mellin TN; Loriaux DL
    J Clin Endocrinol Metab; 1987 Jul; 65(1):188-93. PubMed ID: 3584395
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Species differences in prostatic steroid 5 alpha-reductases of rat, dog, and human.
    Liang T; Cascieri MA; Cheung AH; Reynolds GF; Rasmusson GH
    Endocrinology; 1985 Aug; 117(2):571-9. PubMed ID: 4017948
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.