These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

130 related articles for article (PubMed ID: 7718586)

  • 21. Molecular dynamics simulations of bovine cathepsin B and its complex with CA074.
    Yamamoto A; Tomoo K; Miyagawa H; Takaoka Y; Sumiya S; Kitamura K; Ishida T
    Chem Pharm Bull (Tokyo); 2000 Apr; 48(4):480-5. PubMed ID: 10783065
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Substrate specificity of bovine cathepsin B and its inhibition by CA074, based on crystal structure refinement of the complex.
    Yamamoto A; Tomoo K; Hara T; Murata M; Kitamura K; Ishida T
    J Biochem; 2000 Apr; 127(4):635-43. PubMed ID: 10739956
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Structural basis of inhibition of cysteine proteases by E-64 and its derivatives.
    Matsumoto K; Mizoue K; Kitamura K; Tse WC; Huber CP; Ishida T
    Biopolymers; 1999; 51(1):99-107. PubMed ID: 10380357
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Revised definition of substrate binding sites of papain-like cysteine proteases.
    Turk D; Guncar G; Podobnik M; Turk B
    Biol Chem; 1998 Feb; 379(2):137-47. PubMed ID: 9524065
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution.
    Tsunemi M; Matsuura Y; Sakakibara S; Katsube Y
    Biochemistry; 1996 Sep; 35(36):11570-6. PubMed ID: 8794736
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Structure of rat procathepsin B: model for inhibition of cysteine protease activity by the proregion.
    Cygler M; Sivaraman J; Grochulski P; Coulombe R; Storer AC; Mort JS
    Structure; 1996 Apr; 4(4):405-16. PubMed ID: 8740363
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Carboxy-monopeptidase substrate specificity of human cathepsin X.
    Devanathan G; Turnbull JL; Ziomek E; Purisima EO; Ménard R; Sulea T
    Biochem Biophys Res Commun; 2005 Apr; 329(2):445-52. PubMed ID: 15737607
    [TBL] [Abstract][Full Text] [Related]  

  • 28. S2' substrate specificity and the role of His110 and His111 in the exopeptidase activity of human cathepsin B.
    Krupa JC; Hasnain S; Nägler DK; Ménard R; Mort JS
    Biochem J; 2002 Feb; 361(Pt 3):613-9. PubMed ID: 11802791
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Crystal structures of recombinant rat cathepsin B and a cathepsin B-inhibitor complex. Implications for structure-based inhibitor design.
    Jia Z; Hasnain S; Hirama T; Lee X; Mort JS; To R; Huber CP
    J Biol Chem; 1995 Mar; 270(10):5527-33. PubMed ID: 7890671
    [TBL] [Abstract][Full Text] [Related]  

  • 30. E64 [trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane] analogues as inhibitors of cysteine proteinases: investigation of S2 subsite interactions.
    Gour-Salin BJ; Lachance P; Magny MC; Plouffe C; Ménard R; Storer AC
    Biochem J; 1994 Apr; 299 ( Pt 2)(Pt 2):389-92. PubMed ID: 8172599
    [TBL] [Abstract][Full Text] [Related]  

  • 31. The occluding loop in cathepsin B defines the pH dependence of inhibition by its propeptide.
    Quraishi O; Nägler DK; Fox T; Sivaraman J; Cygler M; Mort JS; Storer AC
    Biochemistry; 1999 Apr; 38(16):5017-23. PubMed ID: 10213604
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Design of P1' and P3' residues of trivalent thrombin inhibitors and their crystal structures.
    Slon-Usakiewicz JJ; Sivaraman J; Li Y; Cygler M; Konishi Y
    Biochemistry; 2000 Mar; 39(9):2384-91. PubMed ID: 10694407
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Structure of the complex of proteinase K with a substrate analogue hexapeptide inhibitor at 2.2-A resolution.
    Betzel C; Singh TP; Visanji M; Peters K; Fittkau S; Saenger W; Wilson KS
    J Biol Chem; 1993 Jul; 268(21):15854-8. PubMed ID: 8340410
    [TBL] [Abstract][Full Text] [Related]  

  • 34. New peptidic cysteine protease inhibitors derived from the electrophilic alpha-amino acid aziridine-2,3-dicarboxylic acid.
    Schirmeister T
    J Med Chem; 1999 Feb; 42(4):560-72. PubMed ID: 10052963
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Crystal structure of human procathepsin X: a cysteine protease with the proregion covalently linked to the active site cysteine.
    Sivaraman J; Nägler DK; Zhang R; Ménard R; Cygler M
    J Mol Biol; 2000 Jan; 295(4):939-51. PubMed ID: 10656802
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Identification of dipeptidyl nitriles as potent and selective inhibitors of cathepsin B through structure-based drug design.
    Greenspan PD; Clark KL; Tommasi RA; Cowen SD; McQuire LW; Farley DL; van Duzer JH; Goldberg RL; Zhou H; Du Z; Fitt JJ; Coppa DE; Fang Z; Macchia W; Zhu L; Capparelli MP; Goldstein R; Wigg AM; Doughty JR; Bohacek RS; Knap AK
    J Med Chem; 2001 Dec; 44(26):4524-34. PubMed ID: 11741472
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Crystal structure of papain-E64-c complex. Binding diversity of E64-c to papain S2 and S3 subsites.
    Kim MJ; Yamamoto D; Matsumoto K; Inoue M; Ishida T; Mizuno H; Sumiya S; Kitamura K
    Biochem J; 1992 Nov; 287 ( Pt 3)(Pt 3):797-803. PubMed ID: 1445241
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Use of papain as a model for the structure-based design of cathepsin K inhibitors: crystal structures of two papain-inhibitor complexes demonstrate binding to S'-subsites.
    LaLonde JM; Zhao B; Smith WW; Janson CA; DesJarlais RL; Tomaszek TA; Carr TJ; Thompson SK; Oh HJ; Yamashita DS; Veber DF; Abdel-Meguid SS
    J Med Chem; 1998 Nov; 41(23):4567-76. PubMed ID: 9804696
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Cathepsin B: Active site mapping with peptidic substrates and inhibitors.
    Schmitz J; Gilberg E; Löser R; Bajorath J; Bartz U; Gütschow M
    Bioorg Med Chem; 2019 Jan; 27(1):1-15. PubMed ID: 30473362
    [TBL] [Abstract][Full Text] [Related]  

  • 40. 1,2,4-thiadiazole: a novel Cathepsin B inhibitor.
    Leung-Toung R; Wodzinska J; Li W; Lowrie J; Kukreja R; Desilets D; Karimian K; Tam TF
    Bioorg Med Chem; 2003 Dec; 11(24):5529-37. PubMed ID: 14642597
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.