198 related articles for article (PubMed ID: 7724483)
1. Vitamin K prodrugs: 1. Synthesis of amino acid esters of menahydroquinone-4 and enzymatic reconversion to an active form.
Takata J; Karube Y; Hanada M; Matsunaga K; Matsushima Y; Sendo T; Aoyama T
Pharm Res; 1995 Jan; 12(1):18-23. PubMed ID: 7724483
[TBL] [Abstract][Full Text] [Related]
2. Prodrug for bioreductive activation-independent delivery of menahydroquinone-4: human liver enzymatic activation and its action in warfarin-poisoned human liver.
Takata J; Karube Y; Hanada M; Matsunaga K; Iwasaki H
Biol Pharm Bull; 1999 Feb; 22(2):172-8. PubMed ID: 10077437
[TBL] [Abstract][Full Text] [Related]
3. Vitamin K prodrugs: 2. water-soluble prodrugs of menahydroquinone-4 for systemic site-specific delivery.
Takata J; Karube Y; Hanada M; Matsunaga K; Matsushima Y; Sendo T; Oishi R
Pharm Res; 1995 Dec; 12(12):1973-9. PubMed ID: 8786976
[TBL] [Abstract][Full Text] [Related]
4. Prodrugs for systemic bioreductive activation-independent delivery of phyllohydroquinone, an active form of phylloquinone (vitamin K1). 1: Preparation and in vitro evaluation.
Takata J; Karube Y; Matsunaga K; Hanada M; Hidaka R; Matsushima Y
Biol Pharm Bull; 1999 Dec; 22(12):1347-54. PubMed ID: 10746168
[TBL] [Abstract][Full Text] [Related]
5. Prodrugs of vitamin E. 1. Preparation and enzymatic hydrolysis of aminoalkanecarboxylic acid esters of d-alpha-tocopherol.
Takata J; Karube Y; Nagata Y; Matsushima Y
J Pharm Sci; 1995 Jan; 84(1):96-100. PubMed ID: 7714753
[TBL] [Abstract][Full Text] [Related]
6. Morpholinoalkyl ester prodrugs of diclofenac: synthesis, in vitro and in vivo evaluation.
Tammara VK; Narurkar MM; Crider AM; Khan MA
J Pharm Sci; 1994 May; 83(5):644-8. PubMed ID: 8071813
[TBL] [Abstract][Full Text] [Related]
7. Synthesis, chemical and enzymatic hydrolysis, and bioavailability evaluation in rabbits of metronidazole amino acid ester prodrugs with enhanced water solubility.
Mahfouz NM; Hassan MA
J Pharm Pharmacol; 2001 Jun; 53(6):841-8. PubMed ID: 11428660
[TBL] [Abstract][Full Text] [Related]
8. Prodrugs for Skin Delivery of Menahydroquinone-4, an Active Form of Vitamin K
Goto S; Setoguchi S; Yamakawa H; Watase D; Terada K; Matsunaga K; Karube Y; Takata J
Int J Mol Sci; 2019 May; 20(10):. PubMed ID: 31137618
[TBL] [Abstract][Full Text] [Related]
9. Antitumor Effects and Delivery Profiles of Menahydroquinone-4 Prodrugs with Ionic or Nonionic Promoiety to Hepatocellular Carcinoma Cells.
Setoguchi S; Watase D; Matsunaga K; Yamakawa H; Goto S; Terada K; Ohe K; Enjoji M; Karube Y; Takata J
Molecules; 2018 Jul; 23(7):. PubMed ID: 30013007
[TBL] [Abstract][Full Text] [Related]
10. Prodrugs of 2',3'-dideoxyinosine (DDI): improved oral bioavailability via hydrophobic esters.
Kawaguchi T; Hasegawa T; Seki T; Juni K; Morimoto Y; Miyakawa A; Saneyoshi M
Chem Pharm Bull (Tokyo); 1992 May; 40(5):1338-40. PubMed ID: 1394659
[TBL] [Abstract][Full Text] [Related]
11. Chemical stability of esters of nicotinic acid intended for pulmonary administration by liquid ventilation.
Hsu CH; Jay M; Bummer PM; Lehmler HJ
Pharm Res; 2003 Jun; 20(6):918-25. PubMed ID: 12817898
[TBL] [Abstract][Full Text] [Related]
12. Evaluation of glycolamide esters and various other esters of aspirin as true aspirin prodrugs.
Nielsen NM; Bundgaard H
J Med Chem; 1989 Mar; 32(3):727-34. PubMed ID: 2918521
[TBL] [Abstract][Full Text] [Related]
13. Glycolamide esters as biolabile prodrugs of carboxylic acid agents: synthesis, stability, bioconversion, and physicochemical properties.
Nielsen NM; Bundgaard H
J Pharm Sci; 1988 Apr; 77(4):285-98. PubMed ID: 3379586
[TBL] [Abstract][Full Text] [Related]
14. Synthesis, chemical and enzymatic hydrolysis, and aqueous solubility of amino acid ester prodrugs of 3-carboranyl thymidine analogs for boron neutron capture therapy of brain tumors.
Hasabelnaby S; Goudah A; Agarwal HK; abd Alla MS; Tjarks W
Eur J Med Chem; 2012 Sep; 55():325-34. PubMed ID: 22889558
[TBL] [Abstract][Full Text] [Related]
15. In vitro and in vivo study of water-soluble prodrugs of dexanabinol.
Pop E; Rachwal S; Vlasak J; Biegon A; Zharikova A; Prokai L
J Pharm Sci; 1999 Nov; 88(11):1156-60. PubMed ID: 10564064
[TBL] [Abstract][Full Text] [Related]
16. Pharmacokinetic studies of naproxen amides of some amino acid esters with promising colorectal cancer chemopreventive activity.
Aboul-Fadl T; Al-Hamad SS; Fouad EA
Bioorg Chem; 2018 Feb; 76():370-379. PubMed ID: 29241109
[TBL] [Abstract][Full Text] [Related]
17. Novel double prodrugs of the iron chelator N,N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid (HBED): Synthesis, characterization, and investigation of activation by chemical hydrolysis and oxidation.
Thiele NA; Abboud KA; Sloan KB
Eur J Med Chem; 2016 Aug; 118():193-207. PubMed ID: 27128183
[TBL] [Abstract][Full Text] [Related]
18. Effect of acylation on the ocular disposition of acyclovir. I: Synthesis, physicochemical properties, and antiviral activity of 2'-esters.
Hughes PM; Krishnamoorthy R; Mitra AK
J Ocul Pharmacol; 1993; 9(4):287-97. PubMed ID: 8106835
[TBL] [Abstract][Full Text] [Related]
19. Lipophilic pyrazinoic acid amide and ester prodrugs stability, activation and activity against M. tuberculosis.
Simões MF; Valente E; Gómez MJ; Anes E; Constantino L
Eur J Pharm Sci; 2009 Jun; 37(3-4):257-63. PubMed ID: 19491013
[TBL] [Abstract][Full Text] [Related]
20. Modulating lipophilicity of rohitukine via prodrug approach: Preparation, characterization, and in vitro enzymatic hydrolysis in biorelevant media.
Kumar V; Bharate SS; Vishwakarma RA
Eur J Pharm Sci; 2016 Sep; 92():203-11. PubMed ID: 27422078
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]